Appendix 4 Included Studies BEME Virtual Interviews in Graduate Medical Education by Jennifer Westrick (13161909)

“…The optimal future state remains unclear, though a hybrid model (e.g., VIs followed by a limited number of in-person second looks) may optimize strengths and weaknesses.…”

Image2_Elabela Attenuates the TGF-β1-Induced Epithelial-Mesenchymal Transition of Peritoneal Mesothelial Cells in Patients Receiving Peritoneal Dialysis.TIF by Shunyun Xie (12898211)

“…Compared with those in patients with stage 5 chronic kidney disease who are not on dialysis, serum ELA levels in patients on PD increased with the improvement of residual renal function at PD duration <36 months and decreased to pre-dialysis levels at PD duration ≥36 months, suggesting that dialysis duration is the main risk factor affecting serum ELA levels in patients on PD. …”

Leukocyte Populations in Human Preterm and Term Breast Milk Identified by Multicolour Flow Cytometry by Stephanie Trend (688419)

“…</p><p>Conclusions</p><p>Flow cytometry is a useful tool to identify and quantify leukocyte subsets in breast milk. …”

Cortical and subcortical regions feature distinct early and late responses during audition. by Sarah H. McGill (22505225)

“…Warmer tones indicate increases in spectral power within maximum-intensity stimulus trials over no-stimulus trials, while cooler tones indicate decreases. <b>(A)</b> Frontal association cortex, (B) centrolateral thalamic nucleus, and (C) primary auditory cortex show early increases in alpha (8-12 Hz), beta (12-30 Hz), and gamma (30-100 Hz) band frequencies with late decreases in alpha and beta frequency bands. …”

Quantitative T₂ and T₂* mapping at 10 weeks post infection. by Brice Masi (798438)

“…(<b>E)</b> Distributions of hepatic T₂* values at 10 weeks post infection showing decreased T₂* values (P < 0.01) in the infected mice (n = 4) compared to controls (n = 5).…”

Data_Sheet_1_The response of nutrient cycle, microbial community abundance and metabolic function to nitrogen fertilizer in rhizosphere soil of Phellodendron chinense Schneid seedl... by Yuanzheng Gu (244592)

“…N10 treatment significantly increased the contents of available phosphorus (AP), available potassium (AK), ammonium nitrogen (NH₄⁺-N), nitrate nitrogen (NO₃⁻-N) and sucrase (SU) activity, as well as fungal diversity and the relative expression abundances of amoA and phoD genes in rhizosphere soil, but observably decreased the total phosphorus (TP) content, urease (UR) activity and bacterial diversity, among which the pH, soil organic matter (SOM), AP, NH₄⁺-N and NO₃⁻-N were the main environmental factors for affecting rhizosphere soil microbial community structure based on RDA and correlation analyses. …”

Image9_Elabela Attenuates the TGF-β1-Induced Epithelial-Mesenchymal Transition of Peritoneal Mesothelial Cells in Patients Receiving Peritoneal Dialysis.TIF by Shunyun Xie (12898211)

“…Compared with those in patients with stage 5 chronic kidney disease who are not on dialysis, serum ELA levels in patients on PD increased with the improvement of residual renal function at PD duration <36 months and decreased to pre-dialysis levels at PD duration ≥36 months, suggesting that dialysis duration is the main risk factor affecting serum ELA levels in patients on PD. …”

Neurophysiological results of patients with acromegaly. by Juan Francisco Martín-Rodríguez (399011)

“…<p>(<b>A</b>) Power spectra differences (frequency range: 1–40 Hz) among patient groups and healthy controls. …”

Data_Sheet_2_Global Burden Attributable to High Low-Density Lipoprotein-Cholesterol From 1990 to 2019.docx by Heyue Du (11229207)

“…Background<p>High low-density lipoprotein-cholesterol (LDL-C) is a public health issue contributing to ischemic heart disease (IHD) and stroke.…”

Image_2_Quercetin activates vitamin D receptor and ameliorates breast cancer induced hepatic inflammation and fibrosis.TIF by Nirmala G. Sannappa Gowda (14666519)

“…Liver enzymes activity was determined using a spectrophotometric assay. The hallmarks of inflammation and fibrosis were determined using Immunohistochemistry. …”

Appendix 3 Pre-COVID Studies BEME Virtual Interviews in Graduate Medical Education by Jennifer Westrick (13161909)

“…The optimal future state remains unclear, though a hybrid model (e.g., VIs followed by a limited number of in-person second looks) may optimize strengths and weaknesses.…”

TMEM98 is genetically downstream of MYRF. by Sarah J. Garnai (6658520)

“…<p>(A-B) Taqman qRT-PCR analysis of RPE expressed genes important for nanophthalmos (<i>Myrf</i>, <i>Best1</i>, <i>Mfrp</i>, <i>Tmem98</i>) in <i>Myrf</i>^<i>+/fl</i>, <i>RxCre;Myrf</i>^<i>+/fl</i> and <i>RxCre;Myrf</i>^<i>fl/fl</i> eyes at P3 (A) and P22 (B). …”

Supplementary Figures from AZD9496: An Oral Estrogen Receptor Inhibitor That Blocks the Growth of ER-Positive and <i>ESR1</i>-Mutant Breast Tumors in Preclinical Models by Hazel M. Weir (2123344)

“…<p>Supplementary Figure 1 contains a Western blot showing the amount of estrogen receptor remaining after treatment of MCF-7 cells with AZD9496, fulvestrant and estradiol alongside GAPDH protein levels as an internal gel loading control; Supplementary Figure 2 shows the rate of decreased detection by mass spectrometry of an estrogen receptor heavy isotype labelled peptide over time after treatment of cells with AZD9496, fulvestrant and tamoxifen and the calculated half life; Supplementary Figure 3 shows the degradation of estrogen receptor α by AZD9496, fulvestrant and estradiol in the presence of +/- 10 μM proteosomal inhibitor MG132; Supplementary Figure 4 contains a Western blot showing the re-emergence over 48 hours of estrogen receptor α following removal of AZD9496, fulvestrant and estradiol compounds from MCF-7 cells; Supplementary Figure 5 shows a bar chart of the measured estradiol levels in the blood of mice over 42 days after implantation of the mice with estrogen pellets to support growth of the MCF-7 cells as a tumour in mice; Supplementary Figure 6 shows the effects of AZD9496, fulvestrant and tamoxifen on mRNA levels of estrogen receptor regulated genes in vitro and in vivo; Supplementary Figure 7 shows the levels of estrogen receptor α protein remaining in tumours from the HCC1428 LTED model after treatment with AZD9496 and fulvestrant.…”

Data_Sheet_1_Characterization of Fructan Metabolism During Jerusalem Artichoke (Helianthus tuberosus L.) Germination.PDF by Jiao Jiao (297582)

“…Ht1-SST (sucrose:sucrose 1-fructosyl transferase, inulin synthesis initiator), and Ht1-FFT (fructan:fructan 1-fructosyl transferase, inulin elongator) expression generally decreased in indoor-grown T. The enzyme activities of 1-FEH and 1-FFT were unchanged during germination in both indoor- and field-grown T and BE/S, whereas 1-SST activity decreased in indoor-grown T, while 1-FEH and 1-FFT activities increased as a function of germination time in BE/S of both indoor- and field-grown tubers. …”

Data_Sheet_1_Altered Insular Subregional Connectivity Associated With Cognitions for Distinguishing the Spectrum of Pre-clinical Alzheimer's Disease.pdf by Siyu Wang (696358)

“…A model consisting of altered insular subnetwork FCs in patients with aMCI was able to appropriately classify 86.5% of the patients with aMCI and CNs, with an AUC of 0.887, 80.4% sensitivity, and 83.6% specificity. …”

The Latitudinal Gradients of PID Species by Vanina Guernier (26588)

“…<div><p>(A) Relationship between PID species richness and latitude across the two hemispheres. …”

Smad3 Inactivation and MiR-29b Upregulation Mediate the Effect of Carvedilol on Attenuating the Acute Myocardium Infarction-Induced Myocardial Fibrosis in Rat by Jie-Ning Zhu (463126)

“…<div><p>Carvedilol, a nonselective β-adrenoreceptor antagonist, protects against myocardial injury induced by acute myocardium infarction (AMI). …”

Data_Sheet_1_Effects of Maternal Deprivation and Complex Housing on Rat Social Behavior in Adolescence and Adulthood.PDF by Jiska Kentrop (5736368)

“…Maternally deprived males – but not females – showed a longer latency to play and a decreased total amount of social play behavior, after a 24 h isolation period. …”

Mitochondrial FAO unaltered in placental cells upon hypoxia. by Philippe Vangrieken (5683748)

“…Data are presented as fold change compared to the control and as mean with SEM. HADH: 3-hydroxyacyl-CoA dehydrogenase. Protein levels of nuclear-encoded sub-units of the ETC including Ndufb8, Sdhb, UQCR2 and ATP5A of respectively complex I, II, III and V, were not affected in placental villous explants exposed for 3 h to hypoxia (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0245155#pone.0245155.s006" target="_blank">S6A Fig</a>). …”

Cellular network estimation and characterisation of cell pairs by two distance measures. by Hiroshi Momiji (3254958)

“…A red + symbol is an outlier found above the whisker, which is defined to be q3 ± 1.5 (q3—q1), where q1 and q3 are the respective 25th and 75th percentiles. …”