Data_Sheet_1_Tubing-Free Microfluidic Microtissue Culture System Featuring Gradual, in vivo-Like Substance Exposure Profiles.pdf by Christian Lohasz (5825933)

“…<p>In vitro screening methods for compound efficacy and toxicity to date mostly include cell or tissue exposure to preset constant compound concentrations over a defined testing period. Such concentration profiles, however, do not represent realistic in vivo situations after substance uptake. …”

Presentation_1_Genome-Wide DNA Methylation Enhances Stemness in the Mechanical Selection of Tumor-Repopulating Cells.pdf by Wei Huang (36889)

“…We found that genes with continuously increasing or decreasing methylation like CREB5/ADAMTS6/LMX1A may also affect the TRC screening process. …”

Image_1_Field Relevant Variation in Ambient Temperature Modifies Density-Dependent Establishment of Plasmodium falciparum Gametocytes in Mosquitoes.tif by Ashutosh K. Pathak (7870094)

“…Anopheles stephensi were challenged with three densities of P. falciparum gametocytes spanning a ~10-fold gradient, and housed under diurnal/daily temperature range (“DTR”) of 9°C (+5°C and −4°C) around means of 20, 24, and 28°C. …”

Raw data. by Donglin Yang (490406)

“…The results showed that the expression of circRNAs in serum exosomes of DN patients was significantly down-regulated, and hsa_circ_0006382 and hsa_circ_0019539 targeted the expression of FGF9 by binding to miR-34a-5p, miR-766-3p, miR-147a and miR-27a-3p. Further verification showed that the expression of FGF9 was decreased in renal tissues of DN patients (AUC = 0.902), and its recombinant protein could inhibit the expression of α-SMA and vimentin in high glucose-induced NRK-52E cells, indicating that activation of the circRNA/miRNA-FGF9 network promotes the EMT of renal tubular epithelial cells. …”

Aberrant RNAPIIpSer2 signal is observed in proximal oocytes when TOP-2 and condensin II are depleted. by Mezmur D. Belew (16632454)

“…For control RNAi 22 gonads across 5 replicates were analyzed, for <i>top-2</i> RNAi 15 gonads were analyzed across 2 replicates, for <i>capg-2</i> RNAi it was 20 gonads across 2 replicates and for <i>top-2/capg-2</i> RNAi it was 10 gonads across a single replicate. …”

The interaction between C9orf72 and Rag GTPases. by Yon Ju Ji (3359057)

“…<p>(A) Co-immunoprecipitation analysis of C9orf72-Flag and HA-Rag. …”

Environmental enrichment increases adult neurogenesis in APP_Sw,Ind mice. by Jorge Valero (230721)

“…<p>(A) Confocal microscopy images showing BrdU (green) positive cells in the granule cell layer (GCL; dashed lines). …”

2D MnTe/rGO Hybrid Structure for Moisture Energy Harvesting by Partha Kumbhakar (9410332)

“…The MnTe/rGO hybrid structure also absorbs a low amount of moisture from ambient humid (RH ∼ 90%) air, resulting in electrical output up to ∼125 mV within ∼15 s. …”

Targeted Resequencing of the Pericentromere of Chromosome 2 Linked to Constitutional Delay of Growth and Puberty by Diana L. Cousminer (747917)

“…Recently, we published a study identifying significant linkage between a locus at the pericentromeric region of chromosome 2 (chr 2) and CDGP in Finnish families. …”

Data Sheet 1_miR-223 alleviates DSS-induced colitis by prompting macrophage M2 polarization through PPAR-γ/FOXO1 signaling.pdf by Juanjuan Zhang (432819)

“…Background<p>Macrophage polarization represents a promising therapeutic target for inflammatory bowel disease (IBD). …”

National Assessment of Statin Therapy in Patients Hospitalized with Acute Myocardial Infarction: Insight from China PEACE-Retrospective AMI Study, 2001, 2006, 2011 by Lihua Zhang (22614)

“…The use of statin, and the intensity of their use, has not been described in acute myocardial infarction patients in China, a country with a rapidly growing burden of cardiovascular disease.…”

Image_3_Liver X Receptor Alpha Is Important in Maintaining Blood-Brain Barrier Function.TIF by Elien Wouters (7108709)

“…This was accompanied by higher numbers of infiltrating leukocytes, increased endothelial VCAM-1 expression, and decreased expression of the tight junction molecule claudin-5. …”

Ecological efficiency index system. by Dalai Ma (17847101)

“…Within them, the CCD of Chengdu is the highest, Chongqing has achieved the largest stage leap. (4) The global Moran’s I consistently remained positive and exhibited a tendency of initially rising and subsequently falling, indicating that the spatial aggregation effect of CCD-GFEE first increased and then decreased. (5) The CCD-GFEE driving factors are examined using the spatial econometric model, and it has been observed that the impact of population size and government intervention on CCD-GFEE is negative, while the impact of industrial structure, technological progress and economic level on the coupling and coordination of CCD-GFEE is positive. …”

Administration of CORM-2 does not improve m-RCT in vivo in diabetic mice. by Karen Alejandra Méndez-Lara (5819492)

“…(A) Total plasma levels of [³H]-cholesterol. …”

Conceptual model. by Dalai Ma (17847101)

“…Within them, the CCD of Chengdu is the highest, Chongqing has achieved the largest stage leap. (4) The global Moran’s I consistently remained positive and exhibited a tendency of initially rising and subsequently falling, indicating that the spatial aggregation effect of CCD-GFEE first increased and then decreased. (5) The CCD-GFEE driving factors are examined using the spatial econometric model, and it has been observed that the impact of population size and government intervention on CCD-GFEE is negative, while the impact of industrial structure, technological progress and economic level on the coupling and coordination of CCD-GFEE is positive. …”

Data_Sheet_1_From Chloroplast Biogenesis to Chlorophyll Accumulation: The Interplay of Light and Hormones on Gene Expression in Camellia sinensis cv. Shuchazao Leaves.xlsx by Linlin Liu (426425)

“…Four major metabolites in the chlorophyll biosynthesis pathway namely Chl a, Chl b, DPP, and Mg-Proto IX increased under shade conditions while PBG decreased significantly. …”

Supplementary Material for: Drug Lag for Inflammatory Bowel Disease Treatments in the East and West by Okabayashi S. (5822303)

“…In Asia, the proportion of unapproved IBD drugs was the lowest in Japan at 33.3% (4/12) for CD and 23.1% (3/13) for UC; South Korea had the shortest lag for CD at 13.2 (0–133.1) months and the Philippines had the shortest lag for UC at 9.9 (0.6–176.2) months, but these countries still had longer lag periods than the West. However, a proportion of unapproved drugs and approval lag has decreased considerably in Asia since the start of the biologics era. …”

Table_1_Field Relevant Variation in Ambient Temperature Modifies Density-Dependent Establishment of Plasmodium falciparum Gametocytes in Mosquitoes.docx by Ashutosh K. Pathak (7870094)

“…Anopheles stephensi were challenged with three densities of P. falciparum gametocytes spanning a ~10-fold gradient, and housed under diurnal/daily temperature range (“DTR”) of 9°C (+5°C and −4°C) around means of 20, 24, and 28°C. …”

Supplementary Material for: Poly-(ADP-Ribose) Polymerase-1 Promotes Prothrombin Gene Transcription and Produces Des-Gamma-Carboxy Prothrombin in Hepatocellular Carcinoma by Taniguchi T. (3908848)

“…An electrophoretic mobility shift assay (EMSA) was performed using a biotin end-labeled DNA. <b><i>Results:</i></b> The prothrombin mRNA levels in all 5 DCP producing cell lines were appreciably high. …”

PRISMA flow diagram. by Isadora de Albuquerque Falcão Feitosa (19200317)

“…<div><p>Introduction</p><p>Obesity is a silent pandemic affecting all ages and is a component of metabolic syndrome. …”