Huaier Aqueous Extract Inhibits Ovarian Cancer Cell Motility via the AKT/GSK3β/β-Catenin Pathway by Xiaohui Yan (411294)

“…Western blot analysis further validated that Huaier treatment resulted in decreased AKT phosphorylation, enhanced expression of total GSK3β, inhibition of the phosphorylation of GSK3β on S9, reduction of both cytoplasmic β-catenin expression and nuclear β-catenin translocation, and transcriptional repression of several Wnt/β-catenin target genes (<i>DIXDC1, LRP6, WNT5A</i>, and cyclin D1). …”

Table_1_From Raffinose Family Oligosaccharides to Sucrose and Hexoses: Gene Expression Profiles Underlying Host-to-Nematode Carbon Delivery in Cucumis sativus Roots.pdf by Xingyi Wang (4025135)

“…Consistently, stachyose level was significantly increased by ∼2.5 times at the early stage but reduced at the late stage of infection in comparison with the uninfected roots, with a similar trend found for raffinose and galactinol. …”

Data Sheet 1_Integration of host gene regulation and oral microbiome reveals the influences of smoking during the development of oral squamous cell carcinoma.docx by Dan Liang (158243)

“…</p>Methods<p>The OSCC mouse model and smoking mouse model were established using 200 μg/mL 4-nitroquinoline-1-oxide (4NQO) in drinking water and exposure to cigarette smoke (four cigarettes per session, once a day, 5 days a week). Tongue tissues were harvested at 4 weeks and 16 weeks. …”

Atrial Natriuretic Peptide Regulates Ca²⁺ Channel in Early Developmental Cardiomyocytes by Lin Miao (16545)

“…The depression of I_CaL induced by ANP was not affected by either Nω, Nitro-L-Arginine methyl ester (L-NAME), a nitric oxide synthetase (NOS) inhibitor, or KT5823, a cGMP-dependent protein kinase (PKG) selective inhibitor, in either EDS and LDS cells; whereas depression of I_CaL by ANP was entirely abolished by erythro-9-(2-Hydroxy-3-nonyl) adenine (EHNA), a selective inhibitor of type 2 phosphodiesterase(PDE2) in most cells tested.…”

Table_1_Clinical Values and Markers of Radiation-Induced Liver Disease for Hepatocellular Carcinoma With Portal Vein Tumor Thrombus Treated With Stereotactic Body Radiotherapy.xlsx by Jun Jia (112173)

“…In the univariate analysis, not only the CP score class (A or B) but also each different pretreatment CP score (p < 0.05) was a significant predictive factor of RILD. …”

Image_1.TIF by Meng Li (79487)

“…HUVEC were pre-treated with acetate (10 mM), butyrate (5 mM) or propionate (10 mM) for 24 h and then stimulated with LPS (1 μg/ml) or TNFα (1 ng/ml) for 8 h. …”

Additional HAND2 or microRNA-1 could facilitate the progress of human iCM-reprogramming by GMTEMMZ 7 factors (7Fs). by Emre Bektik (4347667)

“…B) The quantification of three subpopulations in panel A showed that additional HAND2 or microRNA-1 significantly decreased the subpopulation of fibroblast-like reprogrammed iCMs, while the CM-like subpopulation was significantly enhanced only in 12W-7Fs-iCMs. …”

Image_3_Fenofibrate Ameliorated Systemic and Retinal Inflammation and Modulated Gut Microbiota in High-Fat Diet-Induced Mice.pdf by Xue Wang (102830)

“…<p>Fenofibrate, as a lipid-lowering drug, has been reported to have a protective effect on the retina independent with plasma lipid levels. …”

Image2_Modulation of the biological network of lumbar spinal stenosis by Tongdu Huoxue Decoction based on clinical metabolomics.PNG by Luhong Ji (14819746)

“…Regarding metabolomics, the levels of 41 differential metabolites were significantly different in the normal group (group NC) compared to group A, and those were significantly restored after treatment with THD, including chenodeoxycholic acid 3-sulfate, taurohyodeoxycholic acid, 3,5-Dihydroxy-4-methoxybenzoic acid, pinocembrin. …”

Data_Sheet_1_G721-0282 Exerts Anxiolytic-Like Effects on Chronic Unpredictable Mild Stress in Mice Through Inhibition of Chitinase-3-Like 1-Mediated Neuroinflammation.DOCX by Hyeon Joo Ham (7623410)

“…<p>Chronic stress is thought to be a major contributor to the onset of mental disorders such as anxiety disorders. …”

Peroxide-induced disruption of secondary biochemical pathways. by Carlo Giannangelo (8053910)

“…Pathway enrichment analysis showing the percentage of significantly perturbed metabolites (Welch’s <i>t</i> test; P<i>-</i>value < 0.05 and fold change > 1.5) as a function of metabolite class for extended (3, 6 and 9 h) exposure with OZ277, OZ439 (both 300 nM) and DHA (100 nM). …”

Data_Sheet_1_Mental health disparities in Latinx immigrant communities residing in the United States during COVID-19: Implications for policy and practice.docx by María Pineros-Leano (10192295)

“…Key themes identified describing the impact of COVID-19 on the mental health needs of Latinx families included: (1) exacerbation of mental health symptoms, (2) financial stressors, (3) preoccupation regarding transnational lives, (4) secondary needs becoming more salient, and (5) immigration status as a main driver of inequality.…”

Reptin Regulates DNA Double Strand Breaks Repair in Human Hepatocellular Carcinoma by Anne-Aurélie Raymond (724178)

“…These defects in activation and/or recruitment of repair proteins were not due to a decreased number of DSBs as measured by the COMET assay. …”

Averages (%) of foods containing appropriate calcium levels (to achieve adequate calcium intake) in food groups by Sadegh Samadi Foroushani (741351)

“…<div><br><div><b>Suggested citation:</b> Forouzesh A, Forouzesh F, Samadi Foroushani S, Forouzesh A, Zand E. …”

Table1_Olanzapine Promotes the Occurrence of Metabolic Disorders in Conditional TCF7L2-Knockout Mice.xlsx by Ye Yang (297214)

“…RT-qPCR revealed that the CKO mice presented a significantly less transcription of Sp5, an important element of the Wnt signaling pathway.…”

Table_1_The Proof-of-the Concept of Biochar Floating Cover Influence on Swine Manure pH: Implications for Mitigation of Gaseous Emissions From Area Sources.xlsx by Zhanibek Meiirkhanuly (9192503)

“…The objective of this experiment was to test highly alkaline and porous (HAP) modified biochar with pH = 9.2 and red oak (RO) biochar with pH = 7.5 influence on swine manure pH acquired from the outdoor storage and deep pit storage under a barn. …”

Supplementary Material for: Impact of Abemaciclib-induced Serum Creatinine Elevation on Dose Adjustment of Concomitant Medications by figshare admin karger (2628495)

“…Results: Of 221 patients included in this study, 30.8% had grade ≥2 Scr elevation at 1 month post-ABE initiation, increasing to 56.6% after 2 years. CCr significantly decreased after ABE initiation compared with that at baseline (median [interquartile range]: 44.5 [34.7–55.7] mL/min vs. 61.6 [49.3–81.1] mL/min, P < 0.01). …”

Table1_Somatostatin and Its Receptors in Myocardial Ischemia/Reperfusion Injury and Cardioprotection.xlsx by Imre Vörös (10175693)

“…Furthermore, in a translational porcine closed-chest acute myocardial infarction model, ischemic preconditioning increased plasma SST-like immunoreactivity. …”

Data_Sheet_2_Analysis of gut microbiome composition, function, and phenotype in patients with osteoarthritis.docx by Su Liu (1965895)

“…Prevotella could distinguish between OA patients and healthy people with a better diagnostic power (AUC = 77.5%, p < 0.001, 95% CI: 66.9–88.1%). …”

Data Sheet 2_Beyond salt tolerance: SOS1-13’s pivotal role in regulating the immune response to Fusarium oxysporum in Solanum phureja.docx by Liqin Liang (652560)

“…Furthermore, the expression of SA and JA response-related genes (NbPR5 and NbPR12) was up-regulated in NbSOS1-13-silenced plants.…”