Image_1_Cell origin and genome profile difference of penoscrotum invasive extramammary Paget disease compared with its in situ counterpart.jpeg by Yamin Rao (13166352)

“…In our cohort, invasive pEMPD presented increased expression of androgen receptor and decreased MUC5CA expression, and these two changes might bring to the shift of invasive phenotype. …”

DataSheet1_Albuca Bracteata Polysaccharides Attenuate AOM/DSS Induced Colon Tumorigenesis via Regulating Oxidative Stress, Inflammation and Gut Microbiota in Mice.docx by Ziyan Qin (4058464)

“…In this study, we investigate the properties of polysaccharides of A. bracteate, named ABP. The average molecular weight of ABP was 18.3 kDa and ABP consisted of glucose, mannose, galactose, xylose, galacturonic acid, glucuronic acid at a molar ratio of 37.8:8:2.5:1.7:1:1. …”

Table 1_Real-world first-line serplulimab therapy for advanced esophageal cancer: effectiveness, safety, and clinical implications.docx by Fei Yan (128878)

“…The median OS was not reached (95% CI: 13.27-NR), with a 1-year OS rate of 73.5% (95% CI: 60.4–89.3%). …”

Prediction of bleeding risk in patients taking vitamin K antagonists using thrombin generation testing by Saartje Bloemen (820484)

“…In conclusion, bleeding in patients taking VKAs is associated with a decreased whole blood ETP and peak as well as with an increased HAS-BLED score.…”

Table2_Olanzapine Promotes the Occurrence of Metabolic Disorders in Conditional TCF7L2-Knockout Mice.xlsx by Ye Yang (297214)

“…RT-qPCR revealed that the CKO mice presented a significantly less transcription of Sp5, an important element of the Wnt signaling pathway.…”

Irisin Ameliorates Hypoxia/Reoxygenation-Induced Injury through Modulation of Histone Deacetylase 4 by Yu Tina Zhao (3359159)

“…Western blotting was employed to determine active-caspase 3, annexin V, and HDAC4 expression. As compared to wild type H9c2 group, HDAC4 overexpression remarkably led to a great increase in cell death as evident by the increased lactate dehydrogenase (LDH) leakage, ratio of caspase-3-positive cells as well as the upregulated levels of active-caspase 3 and annexin V shown by western blot analysis. …”

Differential Effects of Short-Term Treatment with Two AT₁ Receptor Blockers on Diameter of Pial Arterioles in SHR by Sébastien Foulquier (138858)

“…In the first study, 4-month-old male SHR were treated with telmisartan (TELMI, 2 mg/kg per day) or candesartan cilexetil (CANDE, 10 mg/kg per day) and compared to vehicle treated SHR and normotensive WKY. In a second study, SHR were treated with CANDE, pioglitazone (a PPAR-gamma agonist, PIO 2.5 mg/kg per day) or CANDE+PIO, compared to TELMI. …”

DataSheet_1_Magnetic Resonance Imaging Correlates of Immune Microenvironment in Glioblastoma.pdf by Alessandro Salvalaggio (8780132)

“…MRI features may represent a novel tool for investigating the microenvironment of GBM.…”

Muscle oxygenation in vastus lateralis and gastrocnemius during incremental running exercise: effect of exercise intensity, VO2max, sex and age by Hugo Kerhervé (618369)

“…The aim of this study was to describe the effect of exercise intensity, maximum oxygen utilisation (V ̇O_2MAX), sex and age on vastus lateralis (VL) and gastrocnemius (Gn) muscle oxygenation measured using near-infrared spectroscopy (NIRS) during incremental running exercise to exhaustion, in a participant group having a large range of V ̇O_2MAX.…”

Data_Sheet_1_Involvement of Gut Microbiota in the Development of Psoriasis Vulgaris.doc by Chaonan Sun (4681345)

“…Passing flatus and constipation were significantly correlated with psoriasis (p < 0.05 in both cases). (2) The abundance of Ruminococcaceae family, Coprococcus_1 genus, and Blautia genus were decreased with psoriasis improvement (p < 0.05, respectively), which had been demonstrated significantly increased in psoriasis. (3) Mice receiving psoriatic microbes transplantation showed delayed recovery of psoriasiform dermatitis and less reduction of interleukin (IL)-17A than those receiving healthy microbiota or blank control (p < 0.05 and p < 0.01, respectively).…”

Data_Sheet_1_An Integrated Omics Approach Uncovers the Novel Effector Ecp20-2 Required for Full Virulence of Cladosporium fulvum on Tomato.docx by Mansoor Karimi-Jashni (12997986)

“…The Ecp20-2 gene encodes a small secreted protein of 149 amino acids with a predicted signal peptide of 17 amino acids. …”

Data_Sheet_1_New insights into the evaluation criteria for high-quality deep marine shale gas reservoirs in the Longmaxi formation: Evidence from organic matter pore development ch... by Boyuan Zhu (12754736)

“…Furthermore, the improved model decreased the relative error in predicting the OM porosity by about 32.5%. …”

Phospholipase C zeta profiles are indicative of optimal sperm parameters and fertilisation success in patients undergoing fertility treatment. by Kashir, Junaid

“…Male recruitment criteria required a minimum sperm count of 5 × 10 spermatozoa/mL, while all female patients included in this study yielded at least five oocytes for treatment. …”
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DataSheet_1_Single-cell RNA transcriptomics reveals differences in the immune status of alcoholic and hepatitis B virus-related liver cirrhosis.docx by Pengpeng Zhang (583380)

“…This study explored the differences in the immune status of alcoholic and HBV-related liver cirrhosis.</p>Methods<p>A total of 15 human liver samples from the Third Xiangya Hospital of Central South University, including five healthy controls (HC group), five alcoholic cirrhosis patients (ALC group), and five HBV-related cirrhosis patients (HBV group) were used. …”

Effect of miR-7974 mimic transfection on proliferation of MDA-MB-453 cells together with changes in protein and gene expression levels of LC3B. by Stralina Eneh (21213312)

“…Full length western blots for the <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0322179#pone.0322179.g005" target="_blank">Fig 5A</a> have been provided under supplementary figure (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0322179#pone.0322179.s005" target="_blank">S3 raw image</a>.).…”

An overview of study characteristics. by Akhmedkhan Dubayev (17879559)

“…</p><p>Results</p><p>Twenty-five studies were included (5 randomized controlled trials, 20 non-randomized controlled trials). …”

sCLU protects cells from senescence. by Xiuquan Luo (579204)

“…<p>(A) sCLU was knocked down in an IMR-90 pooled population containing a lentiviral-mediated inducible shRNA-sCLU construct cultured in presence of doxycycline (dox), while expression of sCLU was not affect in the same pooled population in the absence of doxycycline (dox). …”

Numerical model. by Hai Rong (18422937)

“…When the lateral stress coefficient and joint angle are the same, an increase in initial in-situ stress results in a reduction in the area of the blasting damage zone. (2) Under the same initial in-situ stress conditions, the area of the blasting damage zone initially increases and then decreases with an increasing joint angle. …”

Factors influencing LVC in healthy adults (Werden Abrams et al., 2023) by Sophia Werden Abrams (16972306)

“…</p><p dir="ltr"><b>Method:</b> A retrospective analysis of 195 healthy adults (85 men, 110 women; age range: 21–89 years) who participated in a videofluoroscopic swallowing study was completed. …”

Summary of NOS bias assessments. by Akhmedkhan Dubayev (17879559)

“…</p><p>Results</p><p>Twenty-five studies were included (5 randomized controlled trials, 20 non-randomized controlled trials). …”