Video_8_In silico Description of LAT1 Transport Mechanism at an Atomistic Level.MPG by Luca Palazzolo (5681993)

“…<p>The molecular mechanism of transport mediated by LAT1, a sodium-independent antiporter of large neutral amino acids, was investigated through in silico procedures, specifically making reference to two transported substrates, tyrosine (Tyr) and leucine methyl ester (LME), and to 3,5-diiodo-L-tyrosine (DIT), a well-known LAT1 inhibitor. …”

ATP-Sensitive K⁺ Channel Knockout Induces Cardiac Proteome Remodeling Predictive of Heart Disease Susceptibility by D. Kent Arrell (2347204)

“…Ontological annotation stratified the K_ATP channel-dependent protein cohort into a predominant bioenergetic module (63 resolved identities), with additional focused sets representing signaling molecules (6), oxidoreductases (8), chaperones (6), and proteins involved in catabolism (6), cytostructure (8), and transcription and translation (5). …”

Synapsin I Lost from One Bouton Is Incorporated into Adjacent Boutons by Shlomo Tsuriel (19611)

“…<div><p>An axonal segment expressing both CFP (A) and PA-GFP:Synapsin I (B).</p> <p>(C) Higher magnification of region enclosed in rectangle in (B). …”

WHO BMI classification for adults. by Shane Naidoo (20148021)

“…</p><p>Results</p><p>The sample had a mean BMI of 27.53 kg/m² (95% CI [26.99, 28.07], SD = 5.49), with an obesity prevalence of 31.82%. …”

Table_1_In vitro Characterization of Gut Microbiota-Derived Bacterial Strains With Neuroprotective Properties.pdf by Suaad Ahmed (7407479)

“…<p>Neurodegenerative diseases are disabling, incurable, and progressive conditions characterized by neuronal loss and decreased cognitive function. Changes in gut microbiome composition have been linked to a number of neurodegenerative diseases, indicating a role for the gut-brain axis. …”

Data_Sheet_1_In silico Description of LAT1 Transport Mechanism at an Atomistic Level.PDF by Luca Palazzolo (5681993)

“…<p>The molecular mechanism of transport mediated by LAT1, a sodium-independent antiporter of large neutral amino acids, was investigated through in silico procedures, specifically making reference to two transported substrates, tyrosine (Tyr) and leucine methyl ester (LME), and to 3,5-diiodo-L-tyrosine (DIT), a well-known LAT1 inhibitor. …”

Table_1_Independent and joint influence of depression and advanced lung cancer inflammation index on mortality among individuals with chronic kidney disease.DOCX by Jie Zhou (28945)

“…Weighted multivariate COX regression models, restricted cubic splines (RCS) models, and stratified analyses were used to investigate the association of PHQ-9 scores and ALI with all-cause mortality.</p>Results<p>During a median follow-up of 5.8 years (interquartile range 3.4–8.6 years), a total of 985 patients died (25.0%). …”

Table 2_Metformin-associated gut microbiota remodeling correlates with reinvigorated splenic immunity in aged mice: microbiome-immune crosstalk via the gut-spleen axis.xlsx by Shu-Qin Ding (9319682)

“…Pro-inflammatory cytokines (Ifng, Il17a, Il1b, Il6) decreased, while anti-inflammatory markers (Arg1, Tgfb1) rose. …”

Data_Sheet_2_In silico Description of LAT1 Transport Mechanism at an Atomistic Level.PDF by Luca Palazzolo (5681993)

“…<p>The molecular mechanism of transport mediated by LAT1, a sodium-independent antiporter of large neutral amino acids, was investigated through in silico procedures, specifically making reference to two transported substrates, tyrosine (Tyr) and leucine methyl ester (LME), and to 3,5-diiodo-L-tyrosine (DIT), a well-known LAT1 inhibitor. …”

Ischemic Acute Kidney Injury Perturbs Homeostasis of Serine Enantiomers in the Body Fluid in Mice: Early Detection of Renal Dysfunction Using the Ratio of Serine Enantiomers by Jumpei Sasabe (516628)

“…In the serum, the level of D-serine gradually increased after renal IRI in parallel with that of creatinine, whereas the L-serine level decreased sharply in the early phase after IRI. The increase of D-serine was suppressed in part by genetic inactivation of a D-serine-degrading enzyme, D-amino acid oxidase (DAO), but not by disruption of its synthetic enzyme, serine racemase, in mice. …”

Table_3_Genome-Wide Identification of Rapid Alkalinization Factor Family in Brassica napus and Functional Analysis of BnRALF10 in Immunity to Sclerotinia sclerotiorum.xlsx by Yu-Han He (12004193)

“…The oilseed rape genome carried 61 RALFs, half of them were atypical, containing a less conserved YISY motif and lacking a RRXL motif or a pair of cysteines. …”

An outbreak of HIV infection among people who inject drugs linked to injection of propofol in Taiwan by Yu-Ching Huang (815925)

“…The HIV epidemic curve among PWID revealed an outbreak of 82 in 2015, which then decreased to 43 in 2016 after propofol began to be regulated as a Schedule 4 controlled drug in August 2015. …”

Table 4_Metformin-associated gut microbiota remodeling correlates with reinvigorated splenic immunity in aged mice: microbiome-immune crosstalk via the gut-spleen axis.xlsx by Shu-Qin Ding (9319682)

“…Pro-inflammatory cytokines (Ifng, Il17a, Il1b, Il6) decreased, while anti-inflammatory markers (Arg1, Tgfb1) rose. …”

Consortial population relaxation oscillator. by James J. Winkle (7181861)

“…<a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1009381#pcbi.1009381.g005" target="_blank">Fig 5B</a>). …”

Data_Sheet_1_Petrogenesis of the Late Oligocene Takht batholith, Southeastern Iran: Implications for the Diachronous Nature of the Arabia–Eurasia Collision.PDF by Kwan-Nang Pang (9266600)

“…Overall, our results indicate that the Takht batholith is a Cordilleran-type batholith formed beneath a continental or transitional arc of normal crustal thickness. …”

Exposure to lipophilic statins inhibits the expression of <i>CTGF</i> and <i>CYR61</i> induced by stimulation with neurotensin and insulin in PDAC cells. by Fang Hao (535483)

“…The cultures were then stimulated either without (-) or with a combination of 5 nM neurotensin and 10 ng/ml insulin (NT+Ins) for 60 min. …”

T₂* weighted MRI successfully detect massive red cell congestion (RCC) in 1h cardiac death (CD1h) and CD2h kidney grafts. by Jun-Ya Kaimori (410348)

“…<p>(A) T₂* weighted images of CD 0, 1 and 2 h kidney grafts before transplantation. …”

DataSheet4_Nanoscaled biphasic calcium phosphate modulates osteogenesis and attenuates LPS-induced inflammation.ZIP by Yi-Chun Su (17473050)

“…Our results reveal that treating human osteoblasts with 0.5 μg/mL biphasic calcium phosphate nanomaterials results in a marked increase in alkaline phosphatase (ALP) activity and the upregulation of osteogenesis-related genes. …”

DataSheet1_Finasteride Alleviates High Fat Associated Protein-Overload Nephropathy by Inhibiting Trimethylamine N-Oxide Synthesis and Regulating Gut Microbiota.PDF by Zuoyuan Wang (13247373)

“…Finasteride, a competitive and specific inhibitor of type II 5a-reductase, has been reported recently to be able to downregulate plasma TMAO level thus preventing the onset of atherosclerosis by our research group. …”

Poloxamer/Poly(ethylene glycol) Self-Healing Hydrogel for High-Precision Freeform Reversible Embedding of Suspended Hydrogel by Arthur Colly (10508947)

“…The usefulness of this approach is distinctly demonstrated through a six-axis printing of a highly complex silicone anatomical model. …”