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98581
Altered p53/p16 expression is linked to urothelial carcinoma progression but largely unrelated to prognosis in muscle-invasive tumors
Published 2023“…</p> <p>p16 immunostaining was absent in normal urothelium but occurred in 63.5% (30.4% strong) of cancers. p16 strongly positive cases increased from pTaG2 low-grade (9.6%) to pTaG3 high-grade tumors (46.5%, <i>p</i> < .0001) but decreased from pTaG3 to pT4 (33.3%; <i>p</i> = .0030). …”
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98582
<i>FoxD(RNAi)</i> animals display abnormal anterior pole, head patterning and midline gene expression.
Published 2014“…<p>(<b>A</b>) Upper panels: animals injected with <i>FoxD</i> dsRNA regenerated normally sized anterior blastemas with one eye (73/130) or smaller blastemas with no eyes (24/130) seven days following amputation. …”
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98583
Table 3_Therapeutic effects and mechanism analysis of Paeonia lactiflora extract (PLE) in menopausal rats with hot flashes.xlsx
Published 2025“…In addition, PLE had the effect of increasing the estradiol content and decreasing the luteinizing hormone content in the serum of rats, and the administration of 160 mg/kg of PLE also significantly increased the 5-hydroxytryptamine content in the serum of rats. …”
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98584
Table 6_Therapeutic effects and mechanism analysis of Paeonia lactiflora extract (PLE) in menopausal rats with hot flashes.xlsx
Published 2025“…In addition, PLE had the effect of increasing the estradiol content and decreasing the luteinizing hormone content in the serum of rats, and the administration of 160 mg/kg of PLE also significantly increased the 5-hydroxytryptamine content in the serum of rats. …”
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98585
Table 7_Therapeutic effects and mechanism analysis of Paeonia lactiflora extract (PLE) in menopausal rats with hot flashes.xlsx
Published 2025“…In addition, PLE had the effect of increasing the estradiol content and decreasing the luteinizing hormone content in the serum of rats, and the administration of 160 mg/kg of PLE also significantly increased the 5-hydroxytryptamine content in the serum of rats. …”
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98586
Datasheet1_Assessing sustainment of health worker outcomes beyond program end: Evaluation results from an infant and young child feeding intervention in Bangladesh.docx
Published 2023“…Between baseline and endline, the intervention increased health workers' knowledge (3.5-point increase in knowledge scores in intervention areas, vs. 1.5-point increase in comparison areas, p < 0.0001); and this improvement persisted to post-endline, suggesting a sustained program effect on knowledge. …”
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98587
Space-based scanpath model design.
Published 2023“…(b) The evidence for each potential saccade target (i.e., each pixel location) is accumulated in the decision variable (cf. <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1011512#pcbi.1011512.e011" target="_blank">Eq (5)</a>) in module (IV). …”
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98588
Table_1_Effect of sodium-glucose transporter 2 inhibitors on sarcopenia in patients with type 2 diabetes mellitus: a systematic review and meta-analysis.docx
Published 2023“…In addition, body water likewise decreased significantly (WMD=-0.96, 95% CI: -1.68 to -0.23, P=0.009).…”
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98589
DataSheet_1_Targeting Aberrantly Elevated Sialyl Lewis A as a Potential Therapy for Impaired Endometrial Selection Ability in Unexplained Recurrent Miscarriage.docx
Published 2022“…</p>Methods<p>Paraffin-embedded placental tissue slides collected from patients experiencing early miscarriages (6–12 weeks) were analyzed using immunohistochemical (IHC) and immunofluorescent (IF) staining. …”
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98590
Datasheet2_Efficacy and safety of Danlou tablets in the treatment of stable angina pectoris with intermingled phlegm and blood stasis syndrome in coronary heart disease: a multicen...
Published 2024“…Objectives<p>In this study, we assessed the clinical efficacy and safety of Danlou tablets in the treatment of stable angina pectoris (SAP) with intermingled phlegm and blood stasis (IPBS), to provide high-quality evidence-based medical evidence for the prevention and treatment of coronary heart disease.…”
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98591
Datasheet1_Efficacy and safety of Danlou tablets in the treatment of stable angina pectoris with intermingled phlegm and blood stasis syndrome in coronary heart disease: a multicen...
Published 2024“…Objectives<p>In this study, we assessed the clinical efficacy and safety of Danlou tablets in the treatment of stable angina pectoris (SAP) with intermingled phlegm and blood stasis (IPBS), to provide high-quality evidence-based medical evidence for the prevention and treatment of coronary heart disease.…”
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98592
DataSheet1_MicroRNA-200a/200b Modulate High Glucose-Induced Endothelial Inflammation by Targeting O-linked N-Acetylglucosamine Transferase Expression.PDF
Published 2018“…</p><p>Methods: HAECs were stimulated with high glucose (25 mM) for 12 and 24 h. Real-time polymerase chain reaction (PCR), western blotting, THP-1 adhesion assay, bioinformatics predication, transfection of miR-200a/200b mimic or inhibitor, luciferase reporter assay, and transfection of siRNA OGT were performed. …”
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98593
Image_1_Effect of sodium-glucose transporter 2 inhibitors on sarcopenia in patients with type 2 diabetes mellitus: a systematic review and meta-analysis.jpeg
Published 2023“…In addition, body water likewise decreased significantly (WMD=-0.96, 95% CI: -1.68 to -0.23, P=0.009).…”
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98594
AMF exposures produce highly localized tissue damage in vivo.
Published 2018“…A mouse after a 4300 W AMF exposure for 1.5 s (d) exhibits a circumferential pattern of damage extending to approximately 0.6 mm from the cavity rim. …”
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98595
<b>Tips and Tricks for Robotic Versius Left Lower Lobectomy</b>
Published 2023“…</p><p dir="ltr">A recent meta-analysis by Zhang et al. revealed that RATS is a feasible and safe alternative to VATS, with low thirty-day mortality and similar morbidity for early stage lung cancer (5). …”
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98596
RNAi-mediated knockdown of p66Shc reduces embryo failure and increases blastocyst development.
Published 2014“…The proportion of 2–4 cell embryos was increased by the negative control siRNA while both p66Shc specific siRNA molecules produced significant decreases in embryo arrest. The distribution of 5–8 cell embryos was unaffected by any treatment. …”
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98597
Screening results using different dilutions of CMBs.
Published 2024“…As expected, the empty plasmid control shows values close to 0, whereas PesCDA<sup>nm</sup> shows an increasing amount of free primary amines formed with a decreasing dilution of CMBs. With a strong activity increase still being visible comparing the 1:10 to the 1:5 dilution, we settled on the 1:10 dilution assuming that the CMBs are saturated with enzymes. …”
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98598
Posterior distributions of <i>x</i><sub>2</sub>(<i>t</i>) in the two-state model experiments.
Published 2022“…<p>(<b>A</b>) corresponds to the measurement noise experiment, <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1010651#pcbi.1010651.g003" target="_blank">Fig 3C</a>. …”
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98599
MgO nanoparticles coated with polyethylene glycol as carrier for 2-Methoxyestradiol anticancer drug
Published 2019“…The studies of absorption and liberation determined that MgO-PEG-2ME NPs incorporated 98.51 % of 2ME while liberation of 2ME was constant during 7 days at pH 2, 5 and 7.35. Finally, the MgO-PEG-2ME NPs decreased the viability of the prostate cancer cell line LNCap suggesting that this nanocomposite is suitable as a drug delivery system for anticancer prostate therapy.…”
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98600
DAF-2 ligands down-regulated in <i>adr-2(-)</i> neural cells.
Published 2023“…All individual data and statistics are included in <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3002150#pbio.3002150.s014" target="_blank">S7 Data</a> under Supporting information.…”