HMGB1 Attenuates Cardiac Remodelling in the Failing Heart via Enhanced Cardiac Regeneration and miR-206-Mediated Inhibition of TIMP-3 by Federica Limana (216501)

“…HMGB1 also enhanced MMP2 and MMP9 activity and decreased TIMP-3 levels. Importantly, miR-206 expression 3 days after HMGB1 treatment was 4-5-fold higher than in control hearts and 20–25 fold higher that in sham operated hearts. …”

OB interneurons are diffusely activated by the contralateral olfactory inputs. by Florence Kermen (362513)

“…(H) The pairwise similarity in interneuron response as a function of the distance separating them (ipsilateral, <i>n</i> = 4 fish; contralateral, <i>n</i> = 5 fish, *<i>p</i> < 0.05; Student <i>t</i> test). …”

HIV-1 Diversity, Transmission Dynamics and Primary Drug Resistance in Angola by Inês Bártolo (232611)

“…Evolutionary trends were determined by comparison with a similar survey performed in 2001.</p><p>Results</p><p>47.1% of the viruses were pure subtypes (all except B), 47.1% were recombinants and 5.8% were untypable. …”

Stimulation of pp65-specific CD4+ T cells increased production of stainable IFNγ, MIP-1α and MIP-1β and their respective mRNA, but not RANTES and its mRNA. by Joseph P. Casazza (257693)

“…B) PBMC were incubated with overlapping pp65 peptides, anti-CD154 PE, anti-CD107a Alexa680 and monensin for 5 hr. Cells were then stained as described in <a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1000646#s4" target="_blank">Materials and Methods</a>, and live CD14⁻CD19⁻CD3⁺CD8⁻CD4⁺ memory cells were sorted into CD107⁻CD154⁻, CD107⁻CD154⁺ and CD107⁺CD154⁺ populations as shown. …”

Plots of multiple cells oscillatory clocks versus time. by Robert P. Jenkins (829062)

“…<p>Each lattice is a single cell. Each five minute interval is marked by two columns of 32 cells. …”

The Genetic Legacy of the Pre-Colonial Period in Contemporary Bolivians by Patricia Taboada-Echalar (392334)

“…Bolivia shows a decreasing autosomal molecular diversity pattern along the longitudinal axis, from the Altiplano to the lowlands. …”

Data_Sheet_1_Epidemiology of Pneumocystis jirovecii Pneumonia and (Non-)use of Prophylaxis.docx by Albert Dunbar (8848394)

“…An in-house PJ quantitative PCR (qPCR) was used in each center. A cycle threshold (Ct) value of ≤ 28.5–30 was considered a probable PCP. …”

Comparison of model results with animal interaction data. by Joseph Hickey (6274097)

“…<p>(a) David’s Scores, <i>D</i>, calculated from the mountain goat interaction data of Ref. …”

Total strain energy of fibroblasts on SU-8 nanopillar arrays. by Jasper Foolen (3088503)

“…Pillars have a diameter of 250nm, a height of 1.5μm and center to center distance was 800nm. …”

Delayed centrosome maturation causes asymmetric particle partitioning. by Jing Chen (4762)

“…(B) Time series of dynein distribution with ∼5 min time delay between the centrosome maturation (also see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0034919#pone.0034919.s008" target="_blank">Movie S4</a>). …”

Lac⁺ Mutations and Genome-Wide Mutagenesis Remain Coupled during I-SceI-Mediated Stimulation of Stress-Induced Mutagenesis. by Caleb Gonzalez (270214)

“…Because it takes two days for a Lac⁺ cell to form a colony on lactose minimal medium, these viable cell measurements on days 1, 2 and 3 pertain to Lac⁺ colonies visible on days 3, 4 and 5, respectively. …”

CEP Biomarkers as Potential Tools for Monitoring Therapeutics by Kutralanathan Renganathan (465207)

“…AL-8309A is a serotonin 5-HT_1A receptor agonist.…”

Table 1_Bevacizumab and anlotinib combination therapy acts via HIF-1α suppression to exert synergistic anti-angiogenic and anti-tumor effects in non-small cell lung cancer.docx by Nafeisha Simayi (22262161)

“…B+A inhibited cell viability by 78%, colony formation by 90%, and invasion by 75% in NSCLC cell lines A549 and H1299; downregulated N-cadherin 5.34-fold, vimentin 6.46-fold, and α-SMA 4.35-fold; and upregulated E-cadherin 3.75-fold. …”

LBH589 modulated the expression of surface markers in cancer and immune effector cells. by Jan M. Klein (488544)

“…<p>(<b>A</b>) Flow cytometry for the cell surface marker MICA/B on HL cells after 4 and 16 hours incubation time with 0, 10 or 20 nM LBH589. …”

Bis(β-diketiminate) Rare-Earth-Metal Borohydrides: Syntheses, Structures, and Catalysis for the Polymerizations of l‑Lactide, ε‑Caprolactone, and Methyl Methacrylate by Xiaodong Shen (1542499)

“…The <i>M</i>_n(obsd) values (<i>M</i>_n = the number-average molar mass) of the resulting PCL are in good agreement with <i>M</i>_n(calcd), with a ratio of monomer to <b>6</b> of up to 1000. The polymerization kinetics of l-LA in THF at 20 °C by complex <b>6</b> displays a first-order dependence on the monomer concentration. …”

Vertical zonation and functional diversity of fish assemblages revealed by ROV videos at oil platforms in The Gulf by Ben-Hamadou, Radhouan

“…This work represents the first assessment of reef fish communities inhabiting oil and gas platforms in the Arabian Gulf. A total of 12,822 fish, belonging to 83 taxonomic groups were recorded around the platforms. …”
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Pathogen-Induced AgDscam Splice Form Repertoires Have Increased Affinity to, and Defense Activity against, the Eliciting Pathogen by Yuemei Dong (17509)

“…<div><p>(A) E. coli and P. veronii had increased affinity to both membrane-bound (M) and secreted (S) AgDscam splice form repertoires that were produced by Sua5B cells previously challenged with <i>E. coli (E.c.)…”

Deletion of diploid-specific doxorubicin resistance genes result in cell cycle progression or recombination defects. by Tammy J. Westmoreland (38006)

“…<p>(A) WT and mutant diploid deletion strains were grown to logarithmic phase in liquid YPD. …”

Image1_Optogenetic Manipulations of Amygdala Neurons Modulate Spinal Nociceptive Processing and Behavior Under Normal Conditions and in an Arthritis Pain Model.tiff by Mariacristina Mazzitelli (10869657)

“…Conversely, optical silencing of CeA–CRF neurons or of BLA axon terminals in the CeA decreased the evoked responses of spinal WDR neurons and vocalizations, but not hypersensitivity, in the arthritis pain model. …”

Image2_Optogenetic Manipulations of Amygdala Neurons Modulate Spinal Nociceptive Processing and Behavior Under Normal Conditions and in an Arthritis Pain Model.tiff by Mariacristina Mazzitelli (10869657)

“…Conversely, optical silencing of CeA–CRF neurons or of BLA axon terminals in the CeA decreased the evoked responses of spinal WDR neurons and vocalizations, but not hypersensitivity, in the arthritis pain model. …”