Image_9_CLEC4s as Potential Therapeutic Targets in Hepatocellular Carcinoma Microenvironment.TIF by Yinjiang Zhang (5030006)

“…Furthermore, the expression of CLEC4H1 (ASGR1) and CLEC4H2 (ASGR2) exhibited a significant relation to clinical stages. However, the expression of CLEC4A, CLEC4D, CLEC4E, CLEC4J (FCER2), CLEC4K (CD207), CLEC4G, CLEC4H1, CLEC4M, and CLEC4H2 decreased with tumor progression. …”

The Hepatoselective Glucokinase Activator PF-04991532 Ameliorates Hyperglycemia without Causing Hepatic Steatosis in Diabetic Rats by Derek M. Erion (568011)

“…During a hyperglycemic clamp in Goto-Kakizaki rats, the glucose infusion rate was increased approximately 5-fold with PF-04991532. …”

Image_4_Impact of Computed Tomography-Based, Artificial Intelligence-Driven Volumetric Sarcopenia on Survival Outcomes in Early Cervical Cancer.tif by Qingling Han (11477659)

“…During primary treatment, significant decreases in waist skeletal muscle (median, −3.9%; p < 0.001) and total fat (median, −5.3%; p < 0.001) were observed. …”

Table_1_3D-Printed PCL/PPy Conductive Scaffolds as Three-Dimensional Porous Nerve Guide Conduits (NGCs) for Peripheral Nerve Injury Repair.DOCX by Sanjairaj Vijayavenkataraman (7505000)

“…PCL/PPy scaffolds with three different concentrations of PPy-b-PCL (0.5, 1, and 2% v/v) were fabricated as a mesh (pore size 125 ± 15 μm) and the effect of incorporation of PPy-b-PCL on mechanical properties, biodegradability, and conductivity of the NGCs were studied. …”

Table_6_Impact of Computed Tomography-Based, Artificial Intelligence-Driven Volumetric Sarcopenia on Survival Outcomes in Early Cervical Cancer.docx by Qingling Han (11477659)

“…During primary treatment, significant decreases in waist skeletal muscle (median, −3.9%; p < 0.001) and total fat (median, −5.3%; p < 0.001) were observed. …”

Image_7_CLEC4s as Potential Therapeutic Targets in Hepatocellular Carcinoma Microenvironment.TIF by Yinjiang Zhang (5030006)

“…Furthermore, the expression of CLEC4H1 (ASGR1) and CLEC4H2 (ASGR2) exhibited a significant relation to clinical stages. However, the expression of CLEC4A, CLEC4D, CLEC4E, CLEC4J (FCER2), CLEC4K (CD207), CLEC4G, CLEC4H1, CLEC4M, and CLEC4H2 decreased with tumor progression. …”

Table_1_Current status, trends, and predictions in the burden of silicosis in 204 countries and territories from 1990 to 2019.DOCX by Xinglin Yi (16447332)

“…The age-period-cohort analysis forecasted a decreasing trend of the burden of silicosis from 2019 to 2044.…”

Table_3_Identification of novel gene signature for lung adenocarcinoma by machine learning to predict immunotherapy and prognosis.xlsx by Jianfeng Shu (12518655)

“…Background<p>Lung adenocarcinoma (LUAD) as a frequent type of lung cancer has a 5-year overall survival rate of lower than 20% among patients with advanced lung cancer. …”

DataSheet_1_Identification of novel gene signature for lung adenocarcinoma by machine learning to predict immunotherapy and prognosis.pdf by Jianfeng Shu (12518655)

“…Background<p>Lung adenocarcinoma (LUAD) as a frequent type of lung cancer has a 5-year overall survival rate of lower than 20% among patients with advanced lung cancer. …”

Table 4_The boundaries between PML and PML-IRIS: difficult to define, pathology may predict.docx by Jiamin Chen (388522)

“…</p>Results<p>Notably, 63.2% (12/19) of them had blood CD4+ T-cell counts < 200 cells/μl, and 36.8% (7/19) had ≥ 200 cells/μl. 52.9% (9/17) of the patients had elevated CSF protein, 5.3% (1/19) had decreased CSF glucose. Statistical analysis revealed significant correlations between mass effect and both blood CD4+ T-cell counts (P = 0.022) and CSF protein levels (P < 0.001). …”

Image 2_MIF tautomerase inhibitor TE-11 prevents inflammatory macrophage activation and glycolytic reprogramming while reducing leukocyte migration and improving Crohn’s disease-li... by Eszter Vámos (11081587)

“…Here, we tested TE-11, a potent MIF tautomerase inhibitor (IC₅₀ = 5.63 μmol/dm³) in experimental Crohn’s disease in male mice, in leukocyte recruitment and in inflammatory M1 macrophage activation.…”

Encountering epidemic effects of leaf spot disease (<i>Alternaria brassicae</i>) on <i>Aloe vera</i> by fungal biocontrol agents in agrifields—An ecofriendly approach by Swapan Kumar Ghosh (5007290)

“…<i>harzianum</i>, standardized at a rate of 2.5 L / plot (36 sq ft) (10⁸ spores/ mL) are suggested for the ecofriendly management of this epidemic leaf spot disease of <i>Aloe vera</i> in agricultural fields.…”

The Residue-Based Fluctuation Profiles of the Hsp90-Sgt1 and Hsp90-Sgt1-Rar1 Complexes. by Kristin Blacklock (447270)

“…The NMSF profiles for the Hsp90-NTD domains are shown in blue (molecule 1) and red (molecule 2); the NMSF graphs for the Sgt1-CS domain are in green (molecule 3) and cyan (molecule 4); the NMSF plots for the Rar1-CHORD2 domain are in orange (molecule 5) and magenta (molecule 6). The crystal structure residue numbering was converted to a consecutive numbering. …”

Validation of the optimum formula. by Randa Mohammed Zaki (21637175)

“…The optimized formulation was found to be composed of 19.999, 111.869 and 15 mgs of cholesterol, span 60, and SDC, respectively with a desirability of 0.753. EE%, VS, and ZP were predicted to be 88.4977%, 594.592 nm, and −44.2354 mV, respectively. …”

Image 1_MIF tautomerase inhibitor TE-11 prevents inflammatory macrophage activation and glycolytic reprogramming while reducing leukocyte migration and improving Crohn’s disease-li... by Eszter Vámos (11081587)

“…Here, we tested TE-11, a potent MIF tautomerase inhibitor (IC₅₀ = 5.63 μmol/dm³) in experimental Crohn’s disease in male mice, in leukocyte recruitment and in inflammatory M1 macrophage activation.…”

Derived from inclusions late in the infectious cycle induce aponecrosis in human aortic endothelial cells-1 by Joseph Marino (85091)

“…F: HAEC infected for 72 h with 5 IFU/cell. Note that although the cells are infected with different infection doses and fixed at different time points they both elicit the same cell death morphology, thus excluding a cytotoxic effect and underlining the independency of cell death morphology from infection time. …”

Quantitative analysis of apoptotic cell death by TUNEL assay. by Jiwon Chang (845290)

“…Light red dots were not visible in the negative control zebrafish (A). A comparison of the color intensity between the group treated with 125 μM neomycin and the group treated with 500 μM sodium selenite for 1 h showed that the number of TUNEL-positive cells significantly decreased in the 5 and 6-dpf transgenic zebrafish treated with sodium selenite, and that apoptotic cell death of the neuromasts hair cells was attenuated by sodium selenite (green and red-colored fish in the left column, combination of control and TUNEL reaction (a), × 10; red-colored fish in the left middle column, TUNEL reaction (b), × 10; green-colored fish in the right middle column, control for TUNEL reaction (c), × 10; green and red-colored neuromast in the right column, merge for control and TUNEL reaction by high magnification (d), × 40) (A). …”

Figure 2 from Auranofin Synergizes with Cisplatin in Reducing Tumor Burden of NOTCH-Dependent Ovarian Cancer by Robert J. Lake (22408833)

“…RBPJ occupancy at <i>HES1</i> and <i>HES4</i> promoters decreased in a dose-dependent manner. <i>CDKN1A</i> (p21) served as a negative control. …”

Table_4_CLEC4s as Potential Therapeutic Targets in Hepatocellular Carcinoma Microenvironment.xlsx by Yinjiang Zhang (5030006)

“…Furthermore, the expression of CLEC4H1 (ASGR1) and CLEC4H2 (ASGR2) exhibited a significant relation to clinical stages. However, the expression of CLEC4A, CLEC4D, CLEC4E, CLEC4J (FCER2), CLEC4K (CD207), CLEC4G, CLEC4H1, CLEC4M, and CLEC4H2 decreased with tumor progression. …”

Table_2_Impact of Computed Tomography-Based, Artificial Intelligence-Driven Volumetric Sarcopenia on Survival Outcomes in Early Cervical Cancer.docx by Qingling Han (11477659)

“…During primary treatment, significant decreases in waist skeletal muscle (median, −3.9%; p < 0.001) and total fat (median, −5.3%; p < 0.001) were observed. …”