Data Sheet 3_The novel pleuromutilin derivative 22–((4-((4-nitrophenyl)acetamido)phenyl)thio)deoxy pleuromutilin possesses robust anti-mycoplasma activity both in vitro and in vivo... by Xirui Xia (12075476)

“…</p>Results<p>The results show that compound 16C has low toxicity (LD₅₀ > 5,000 mg/kg). Its pharmacokinetic profile is characterized by a short time to maximum concentration (Tmax = 0.24 h), high bioavailability (F = 71.29%), and short elimination half-life (T_1/2kel) (intramuscular and intravenous administration was 2.20 and 1.89 h, respectively). …”

DataSheet1_QiShenYiQi Pill Ameliorates Cardiac Fibrosis After Pressure Overload-Induced Cardiac Hypertrophy by Regulating FHL2 and the Macrophage RP S19/TGF-β1 Signaling Pathway.pd... by Gulinigaer Anwaier (6903299)

“…QSYQ also inhibited the following: release of RP S19 from the injured myocardium, activation of C5a receptors in monocytes, polarization of macrophages, and release of TGF-β1. …”

DataSheet1_Enhanced Antifungal and Wound Healing Efficacy of Statistically Optimized, Physicochemically Evaluated Econazole-Triamcinolone Loaded Silica Nanoparticles.docx by Safirah Maheen (10327003)

“…The stability of optimized drugs loaded MSNs prepared with 100 gm of oil at pH 5.6 with a stirring time of 2 h was confirmed from a zeta potential value of −25 mV. …”

Lack of LeuB results in increased proteolytic activity during iron starvation caused by leucine shortage. by Nanbiao Long (5900231)

“…(G) Northern blot analyses demonstrating that lack of LeuB significantly decreases <i>leuA</i> transcript levels during iron starvation but not iron sufficiency. …”

FluidFM-mediated injections of liquids and bacteria into enteroid-derived IECs. by Chantal Ernst (9953921)

“…Focused ion beam image of a FluidFM tip: Scale bar: 5 μm. (<b>B</b>) Dye injection into single IECs. …”

Regorafenib sensitizes human breast cancer cells to radiation by inhibiting multiple kinases and inducing DNA damage by Meghna Mehta (8446044)

“…</p> <p>Regorafenib reduced cell proliferation and enhanced radiosensitivity of MDA-MB-231 and SUM159PT cell lines but had no effect on the MCF 10a cells. Clonogenic survival assays showed that the surviving fraction at 2 Gy for both MDA-MB-231 and SUM159PT was reduced from 66.4 ± 8.9 and 88.2 ± 1.7 in controls to 38.1 ± 4.9 and 75.1 ± 1.1 following a 24 hr pretreatment with 10 μM and 5 μM Regorafenib, respectively. …”

Dynamics of conceptual distance <i>d</i> and the growth effects of the data set by Artem Chumachenko (21681455)

“…</p> <p>The analysis of conceptual distance dynamics highlights that the expansion of the dataset, as reflected in the dynamics of <i>N</i> or <i>N</i>₀₀ in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0327793#pone.0327793.s003" target="_blank">S2 Fig</a>, does not affect the behavior of the distance <i>d</i> in the manner predicted by the model in Eq (5) when only the number of background documents of type <i>N</i> ₀₀ increases. …”

DataSheet_1_Segmentation stability of human head and neck cancer medical images for radiotherapy applications under de-identification conditions: Benchmarking data sharing and arti... by Jaakko Sahlsten (13165413)

“…Eight publicly available defacing algorithms were investigated: afni_refacer, DeepDefacer, defacer, fsl_deface, mask_face, mri_deface, pydeface, and quickshear. Using a subset of scans where defacing succeeded (N=29), a 5-fold cross-validation 3D U-net based OAR auto-segmentation model was utilized to perform two main experiments: 1.) comparing original and defaced data for training when evaluated on original data; 2.) using original data for training and comparing the model evaluation on original and defaced data. …”

Interactive “Video Doctor” Counseling Reduces Drug and Sexual Risk Behaviors among HIV-Positive Patients in Diverse Outpatient Settings by Paul Gilbert (90408)

“…</p><h3>Methodology and Findings</h3><p>We conducted a parallel groups randomized controlled trial (December 2003–September 2006) at 5 San Francisco area outpatient HIV clinics. …”

ICS-209-PLUS - An all-hazards dataset mined from the US National Incident Management System 1999-2014 by Lise St. Denis (6634934)

“…This system captures detailed information on incident management costs, personnel, hazard characteristics, values at risk, fatalities, and structural damage. Most (98.5%) of the reports are fire-related, followed in decreasing order by <i>other</i>, hurricane, hazardous materials, flood, tornado, search and rescue, civil unrest, and winter storms. …”

Effect of schistosomiasis on the outcome of patients infected with HIV-1 starting antiretroviral therapy in rural Tanzania by Katarina Stete (213207)

“…After adjustment for age, sex, body mass index, educational attainment, WHO-stage, tuberculosis status, and year of ART initiation, CAA-positivity showed a trend of a decreased hazard of death/LFU (HR: 0.58, 95% CI: 0.32–1.05, p = 0.07), while CD4 count at baseline (HR: 0.86, 95% CI: 0.76–1.00, p = 0.02) and MXD (sum of eosinophils, basophils, and monocytes counts) >1,100 cells/μl (HR: 0.56, 95% CI: 0.34–0.93, p = 0.03) were identified as independently protective factors.…”

Table_1_Application of starch degrading bacteria from tobacco leaves in improving the flavor of flue-cured tobacco.pdf by Yinuo Gong (16454715)

“…After treating flue-cured tobacco with an enzyme preparation prepared by the fermentation of Paenibacillus amylolyticus A17 #, the content of starch, pectin, and cellulose in flue-cured tobacco decreased significantly compared with the control group. …”

Validation of ICC-MS and network analysis. by Steven F. Baker (847771)

“…<p><b>(A)</b> Relative protein abundance of PB2 (red), PA (cyan), and NP (yellow) in PB2 ICC-MS samples shows decreasing capture with increasing competition antibody. …”

Effects of activated vitamin D, alfacalcidol, and low-intensity aerobic exercise on osteopenia and muscle atrophy in type 2 diabetes mellitus model rats by Manabu Akagawa (5866520)

“…After 6 weeks of treatment, ALF and Comb treatments decreased <i>Atrogin-1</i> and <i>REDD1</i>. These results demonstrate that a combination of ALF and Exe improved CSA from the early phase of treatment by stimulating skeletal muscle differentiation and suppressing muscle catabolic genes. …”

Comparisons of <i>Mycosphaerella graminicola</i> genome assembly versions 1 and 2 against that of <i>Stagonospora nodorum</i> isolate SN15. by Stephen B. Goodwin (114865)

“…For example, <i>M. graminicola</i> v2 chromosomes 6 and 16 (B, circle IV) and 12 and 21 (B, circle V) were derived from split version 1 scaffolds 4 (A, circle IV) and 9 (A, circle V), respectively. …”

Table_3_Holocene Vegetation and Plant Diversity Changes in the North-Eastern Siberian Treeline Region From Pollen and Sedimentary Ancient DNA.DOCX by Sisi Liu (420299)

“…Nevertheless, plant species richness is mostly higher than at the forest-tundra site, which shows a slightly decreasing trend. Plant species richness at the open larch forest site fluctuates through time and is higher than the other sites since around 2.5 ka. …”

To What Extent Does the Zintl−Klemm Formalism Work? The Eu(Zn_1−<i>x</i>Ge_<i>x</i>)₂ Series by Tae-Soo You (2073337)

“…As the Ge content increases in this range, <i>a</i> decreases from 4.3631(6) Å to 4.2358(6) Å, while <i>c</i> increases from 4.3014(9) Å to 4.5759(9) Å, resulting in an increasing <i>c</i>/<i>a</i> ratio. …”

Table_2_Holocene Vegetation and Plant Diversity Changes in the North-Eastern Siberian Treeline Region From Pollen and Sedimentary Ancient DNA.XLSX by Sisi Liu (420299)

“…Nevertheless, plant species richness is mostly higher than at the forest-tundra site, which shows a slightly decreasing trend. Plant species richness at the open larch forest site fluctuates through time and is higher than the other sites since around 2.5 ka. …”

Table_1_Holocene Vegetation and Plant Diversity Changes in the North-Eastern Siberian Treeline Region From Pollen and Sedimentary Ancient DNA.XLSX by Sisi Liu (420299)

“…Nevertheless, plant species richness is mostly higher than at the forest-tundra site, which shows a slightly decreasing trend. Plant species richness at the open larch forest site fluctuates through time and is higher than the other sites since around 2.5 ka. …”

Climate, trends and variability of extreme winds along the southwest coast of India by Abdulla, Cheriyeri Poyil

“…The 99th percentile wind speeds during premonsoon, SW monsoon and postmonsoon are 8.8, 12.3 and 8.9 m·s−1, respectively. A significant decreasing trend is observed in the 99th percentile wind speeds during 1979–2021, ranging from 3 to 6 cm·s−1·year−1 off Kerala coast. …”
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