DataSheet3_α-klotho reduces susceptibility to osteoarthritis: evidence from cross-sectional studies and Mendelian randomization.xlsx by Zhao Li (300229)

“…</p>Method<p>A cohort of 12,037 subjects from NHANES (2007-2016) was analyzed. …”

Table 1_Multi-omics analysis and evidence of IL1R1 as a potential biomarker for diabetes-associated intervertebral disc degeneration.xlsx by Meng Yi (7853249)

“…</p>Results<p>Bioinformatics analysis of human data identified three diagnostic biomarkers (S100A12, IL1R1, FCGR2B) and constructed a robust ANN diagnostic model (AUCs: 0.744-0.868). …”

Data_Sheet_1_Trends in outcomes of women with myocardial infarction undergoing primary angioplasty—Analysis of randomized trials.PDF by Zuzana Motovska (4044998)

“…There was an increase in probability for an initial TIMI flow >0 in the later study (1.49 [1.0–2.23]), and also for an optimal procedural result (4.24 [2.12–8.49], p < 0.001). The risk of 30-day mortality decreased by 61% (0.39 [0.17–0.91], p = 0.029).…”

Proposed multiple roles of Helicobacter pylori urease during infection. by Tobias D. Schoep (236475)

“…Other non-enzymatic functions of urease that might contribute to persistence include facilitation of resistance to complement mediated opsonisation <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0015042#pone.0015042-Rokita1" target="_blank">[9]</a>, decreased uptake of <i>H. pylori</i> cells by granulocytes <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0015042#pone.0015042-Makristathis1" target="_blank">[8]</a>, increased <i>H. pylori</i> survival in macrophages <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0015042#pone.0015042-Kuwahara1" target="_blank">[6]</a>, <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0015042#pone.0015042-Schwartz1" target="_blank">[7]</a>, and increased release of nutrients via compromised tight junctions <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0015042#pone.0015042-Wroblewski1" target="_blank">[12]</a> and/or apoptosis of epithelial cells <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0015042#pone.0015042-Ding1" target="_blank">[32]</a>.…”

Table3_A novel m7G methylation–related signature associated with chromosome homeostasis in patients with lung adenocarcinoma.XLSX by Xiaoying Tao (13999797)

“…But the expression of m7G methylation–related genes in LUAD and their correlations with prognosis are still unclear. In this study, we found 12 m7G methylation–related regulators with differential expression between LUAD and normal lung tissues. …”

Video_1_Deletion of Vhl in Dmp1-Expressing Cells Causes Microenvironmental Impairment of B Cell Lymphopoiesis.mov by Betsabel Chicana (12093620)

“…In support of this, VhlcKO BM supernatant contained reduced CXCL12 and elevated EPO levels. Intravital and ex vivo imaging revealed VhlcKO BM blood vessels with increased diameter, volume, and a diminished blood-BM barrier. …”

Data_Sheet_2_The β-Lactamase Inhibitor Boronic Acid Derivative SM23 as a New Anti-Pseudomonas aeruginosa Biofilm.docx by Samuele Peppoloni (462500)

“…Our results indicated that SM23: (1) inhibited biofilm development and production of several virulence factors, such as pyoverdine, elastase, and pyocyanin, without affecting bacterial growth; (2) decreased the levels of 3-oxo-C₁₂-HSL and C₄-HSL, two QS-related autoinducer molecules, in line with a dampened lasR/lasI system; (3) failed to bind to bacterial cells that had been preincubated with P. aeruginosa-conditioned medium; and (4) reduced both biofilm formation and pyoverdine production by P. aeruginosa onto endotracheal tubes, as assessed by a new in vitro model closely mimicking clinical settings. …”

Accuracy of Genomic Selection in a Rice Synthetic Population Developed for Recurrent Selection Breeding by Cécile Grenier (788754)

“…<div><p>Genomic selection (GS) is a promising strategy for enhancing genetic gain. We investigated the accuracy of genomic estimated breeding values (GEBV) in four inter-related synthetic populations that underwent several cycles of recurrent selection in an upland rice-breeding program. …”

Table 1_Evaluating treatment and care outcomes for neuromuscular diseases in a pediatric intermediate care setting.docx by Giacomo Brisca (10963929)

“…</p>Results<p>Sixty-three patients (median age 12, female 58.7%) were included. The majority of admissions were due to neurological issues (39.7%) and respiratory complications (22%), with a significant proportion of patients requiring initiation or potentiation of respiratory support (59%). …”

A mechanistic model produces trends in pattern convergence and divergence similar to those predicted by the statistical framework. by Gaia Tavoni (5451656)

“…In (C), we simulated 10,000 MCs grouped into 500 glomeruli and 100,000 cortical cells, each sampling 7% of the MCs, with odor targeting 12% of the glomeruli, positive feedback targeting 8% of the MCs, and negative feedback targeting all MCs.…”

Table_1_The effect of steamed potato-wheat bread intake on weight, lipids, glucose, and urinary Na+/K+: A randomized controlled trial in Chinese adults.docx by Haiquan Xu (586273)

“…Through a clinical trial, we evaluated the effect of steamed potato bread intake on adults. …”

DataSheet_1_Contribution of aged organic carbon to suspended particulate organic carbon in the western equatorial Indian Ocean.docx by Sujin Kang (456330)

“…<p>We investigated dual carbon isotopes within the vertical water column at sites 67-1 and 67-2 of the western equatorial Indian Ocean to determine the source and age of particulate organic carbon (POC) and thus evaluated the contributions of modern and fossil (aged) POC. …”

Table_4_Physiological and Transcriptomic Responses to Nitrogen Deficiency in Neolamarckia cadamba.xlsx by Lu Lu (392)

“…However, the physiological and molecular impacts of ND on this species have not been well investigated. Here, we studied how N. cadamba responds to ND under hydroponic conditions. …”

Table_3_Transcriptomic profiling revealed the role of 24-epibrassinolide in alleviating salt stress damage in tall fescue (Festuca arundinacea).XLSX by Yao Chen (149006)

“…During the growth period of tall fescue, we found that electrolyte leakage (EL) and malondialdehyde (MDA) were decreased, chlorophyll (Chl) content and antioxidant enzyme activity were increased in leaves of tall fescue in SE group compared with SALT group, indicating that EBL improved the salt tolerance in grasses. …”

Effect of PPi on ΔΨm during near-anoxia in cultured rat neonatal cells. by Junko Shibayama (387144)

“…<p><b>A–C</b>. Control. ΔΨm-dependent signal gradually decreased throughout 10 min of anoxia. …”

Model simulations. by Tianhe Wang (1411282)

“…<p>Predicted central tendency (a) and serial dependence (b) effects for the five models. …”

Supplementary Material for: Risk factors and heart rate variability associated with left ventricular enlargement in patients with frequent premature ventricular contractions by Yang Z. (4129039)

“…The values of SDNN, standard deviation of the averages of NN intervals in all 5-min segments, the square root of the mean of the sum of the squares of differences between adjacent NN intervals, pNN50, low-frequency power (LF), LF/high-frequency power ratio of patients were significantly decreased after ablation (all p<0.05). …”

Data_Sheet_1_The Protective Effects of Ciji-Hua’ai-Baosheng II Formula on Chemotherapy-Treated H22 Hepatocellular Carcinoma Mouse Model by Promoting Tumor Apoptosis.docx by Biqian Fu (6181871)

“…After mice were treated with 5-fluorine pyrimidine (5-FU), they were divided into six groups as untreated group, 5-FU group, 5-FU plus Yangzheng Xiaoji Capsule group and three groups of 5-FU plus different concentrations of CHB-II-F. …”

Odds ratios. by Florian Beissner (361549)

“…<p>Odds ratios, calculated as (A · D)/(B · C), where A is the number of selections of the descriptor for C fiber pain, B the total number of presentations of C- fiber pain minus A, C the number of selection of the descriptor for A_δ fiber pain, and D the total number of presentations of A_δ pain minus C, and 95% confidence intervals, calculated as odds ratio±1.96 · (1/A+1/B+1/C+1/D)^0.5, of the selections of the descriptors for C fiber mediated pain (pooled ratings of blunt mechanical pressure and 5-Hz electrical stimuli) and the number of selections of the descriptors for A_δ mediated pain (pooled ratings of punctate mechanical pressure and laser heat), sorted from top to bottom for decreasing selectivity for C fibers and increasing selectivity for A_δ fibers. …”

IL-24 Inhibits Lung Cancer Cell Migration and Invasion by Disrupting The SDF-1/CXCR4 Signaling Axis by Janani Panneerselvam (703170)

“…<div><p>Background</p><p>The stromal cell derived factor (SDF)-1/chemokine receptor (CXCR)-4 signaling pathway plays a key role in lung cancer metastasis and is molecular target for therapy. …”