Fine Tuning of the Substituents on the N‑Geminal Phosphorus/Silicon-Based Lewis Pairs for the Synthesis of <i>Z</i>‑Type Silyliminophosphoranylalkenes by Jiancheng Li (326041)

“…Reactions of the <i>N</i>-aryl­(diphenylphosphanyl)­aminosilane Ph₂PN­(Ar)­SiCl_3–<i>n</i>Me_<i>n</i> (Ar = 2,4,6-Me₃C₆H₂, <i>n</i> = 0 (<b>1a</b>), 1 (<b>2a</b>), 2 (<b>3a</b>), 3 (<b>4a</b>); Ar = 2,6-<i>i</i>Pr₂C₆H₃, <i>n</i> = 0 (1<b>b</b>), 1 (<b>2b</b>), 2 (<b>3b</b>), 3 (<b>4b</b>)) with methyl propiolate and dimethyl acetylenedicarboxylate (DMAD) give two types of products, the zwitterionic heterocycles [Ph₂PN­(2,4,6-Me₃C₆H₂)­SiCl₃]­(HCCCO₂Me) (<b>5c</b>) and [Ph₂PN­(Ar)­SiCl_3–<i>n</i>Me_<i>n</i>]­(MeO₂CCCCO₂Me) (Ar = 2,4,6-Me₃C₆H₂, <i>n</i> = 0 (<b>5a</b>), 1 (<b>6a</b>), 2 (<b>7a</b>); Ar = 2,6-<i>i</i>Pr₂C₆H₃, <i>n</i> = 0 (<b>5b</b>), 1 (<b>6b</b>), 2 (<b>7b</b>)) and (<i>Z</i>)-silyliminophosphoranylalkene ArNP­(Ph₂)­C­(CO₂Me)C­(CO₂Me)­SiMe₃ (Ar = 2,4,6-Me₃C₆H₂ (<b>8a</b>), 2,6-<i>i</i>Pr₂C₆H₃ (<b>8b</b>)). …”

Ribosome footprinting and polysome profiling reveal DUX4 suppressive effects on translation efficiency. by Danielle C. Hamm (4693915)

“…(<b>E</b>) Gene Ontology analysis for transcripts with significantly decreased ribosome occupancy in 5′ UTR, TIS, and first coding exon in MB135iDUX4 myoblasts treated with a DUX4 pulse+IFNγ versus IFNγ; see <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3002317#pbio.3002317.s011" target="_blank">S3 Data</a>. …”

Fine Tuning of the Substituents on the N‑Geminal Phosphorus/Silicon-Based Lewis Pairs for the Synthesis of <i>Z</i>‑Type Silyliminophosphoranylalkenes by Jiancheng Li (326041)

“…Reactions of the <i>N</i>-aryl­(diphenylphosphanyl)­aminosilane Ph₂PN­(Ar)­SiCl_3–<i>n</i>Me_<i>n</i> (Ar = 2,4,6-Me₃C₆H₂, <i>n</i> = 0 (<b>1a</b>), 1 (<b>2a</b>), 2 (<b>3a</b>), 3 (<b>4a</b>); Ar = 2,6-<i>i</i>Pr₂C₆H₃, <i>n</i> = 0 (1<b>b</b>), 1 (<b>2b</b>), 2 (<b>3b</b>), 3 (<b>4b</b>)) with methyl propiolate and dimethyl acetylenedicarboxylate (DMAD) give two types of products, the zwitterionic heterocycles [Ph₂PN­(2,4,6-Me₃C₆H₂)­SiCl₃]­(HCCCO₂Me) (<b>5c</b>) and [Ph₂PN­(Ar)­SiCl_3–<i>n</i>Me_<i>n</i>]­(MeO₂CCCCO₂Me) (Ar = 2,4,6-Me₃C₆H₂, <i>n</i> = 0 (<b>5a</b>), 1 (<b>6a</b>), 2 (<b>7a</b>); Ar = 2,6-<i>i</i>Pr₂C₆H₃, <i>n</i> = 0 (<b>5b</b>), 1 (<b>6b</b>), 2 (<b>7b</b>)) and (<i>Z</i>)-silyliminophosphoranylalkene ArNP­(Ph₂)­C­(CO₂Me)C­(CO₂Me)­SiMe₃ (Ar = 2,4,6-Me₃C₆H₂ (<b>8a</b>), 2,6-<i>i</i>Pr₂C₆H₃ (<b>8b</b>)). …”

Image_1_The Cholinergic Drug Galantamine Alleviates Oxidative Stress Alongside Anti-inflammatory and Cardio-Metabolic Effects in Subjects With the Metabolic Syndrome in a Randomize... by Carine Teles Sangaleti (10287842)

“…In addition, galantamine significantly alleviated the inflammatory state and insulin resistance, and decreased the low frequency/high frequency ratio of HRV, following 8 and 12 weeks of drug treatment.…”

Data Sheet 1_The effects of acupoint catgut embedding therapy on anthropometric parameters and endocrine function in obese women: a systematic review and meta-analysis.pdf by Shuangqiu Li (8083634)

“…Subgroup analyses suggested that heterogeneity decreased in different control groups and different treatment courses, such as diet guidance (I² = 0.0%) and 12-week treatment duration (I² = 32.9%). …”

DataSheet_1_GhBRX.1, GhBRX.2, and GhBRX4.3 improve resistance to salt and cold stress in upland cotton.docx by Wei Wei (21173)

“…</p>Results and discussion<p>We discovered 12, 6, and 6 BRX genes in Gossypium hirsutum, Gossypium raimondii and Gossypium arboreum, respectively. …”

Effect of Intraoperative High-Dose Remifentanil on Postoperative Pain: A Prospective, Double Blind, Randomized Clinical Trial by Yan-Ling Zhang (259002)

“…Recent studies suggest that high-dose (HD) remifentanil offers sustained analgesia in experimental studies. We thus hypothesized that intraoperative administration of high-dose remifentanil may attenuate postoperative pain.…”

Data_Sheet_3_Efficacy of Glutamine in Treating Severe Acute Pancreatitis: A Systematic Review and Meta-Analysis.PDF by Shi Dong (2855099)

“…In terms of secondary outcomes, Gln supplementation helped restore liver, kidney and immune function, with significantly increased serum albumin (SMD = 1.02, 95% CI: 0.74–1.31, P < 0.00001) and IgG levels (MD = 1.24, 95% CI: 0.82–1.67, P < 0.00001), and decreased serum creatinine (Scr) (MD = −12.60, 95% CI: −21.97 to −3.24, P = 0.008), and inflammatory indicators such as C-reaction protein (CRP) (SMD = −1.67, 95% CI: −2.43 to −0.90, P < 0.0001).…”

Experimental Gingivitis Induces Systemic Inflammatory Markers in Young Healthy Individuals: A Single-Subject Interventional Study by Jörg Eberhard (280441)

“…This local inflammation was associated with a systemic increase in hsCRP (0.24 mg/L, <em>P</em> = 0.038), IL-6 (12.52 ng/L, <em>P</em> = 0.0002) and MCP-1 (9.10 ng/l, <em>P</em> = 0.124) in peripheral blood samples between baseline and day 21, which decreased at day 42. …”

Table_1_Total and cause-specific mortality associated with meat intake in a large cohort study in Korea.docx by Anthony Kityo (14782057)

“…Background<p>Asia has experienced a large increase in meat intake in the past decade, yet the health impact of meat intake is not well studied.</p>Objective<p>We examined the association of meat intake with all-cause, cancer and cardiovascular disease (CVD) mortality in an Asian country.…”

Prostaglandin-E2 Mediated Increase in Calcium and Phosphate Excretion in a Mouse Model of Distal Nephron Salt Wasting by Manoocher Soleimani (486415)

“…Confirmatory studies revealed decreases in the expression levels of sodium phosphate transporter-2 isoforms a and c, increases in the expression of cytochrome p450 family 4a isotypes 12 a and b, as well as prostaglandin E synthase 1, and cyclooxygenases 1 and 2. …”

Image_1_Seizures regulate the cation-Cl− cotransporter NKCC1 in a hamster model of epilepsy: implications for GABA neurotransmission.JPEG by Juan-Manuel Bonet-Fernández (16415964)

“…A complementary analysis of NKCC1 gene slc12a2 expression was conducted by real-time PCR. …”

Development of a gastroretentive delivery system for acyclovir by 3D printing technology and its <i>in vivo</i> pharmacokinetic evaluation in Beagle dogs by Soyoung Shin (669783)

“…By X-ray imaging, we showed that the developed GR system stayed in the stomach for more than 12 h. …”

Image_1_Safety and Efficacy of Spironolactone in Dialysis-Dependent Patients: Meta-Analysis of Randomized Controlled Trials.TIF by Jing Liu (38537)

“…However, LVEF (MD = 2.63, P = 0.05), systolic BP (MD = −4.61, P = 0.14) and diastolic BP (MD = −0.12, P = 0.94) did not change between two groups after treatment. …”

Data_Sheet_1_Efficacy of Glutamine in Treating Severe Acute Pancreatitis: A Systematic Review and Meta-Analysis.PDF by Shi Dong (2855099)

“…In terms of secondary outcomes, Gln supplementation helped restore liver, kidney and immune function, with significantly increased serum albumin (SMD = 1.02, 95% CI: 0.74–1.31, P < 0.00001) and IgG levels (MD = 1.24, 95% CI: 0.82–1.67, P < 0.00001), and decreased serum creatinine (Scr) (MD = −12.60, 95% CI: −21.97 to −3.24, P = 0.008), and inflammatory indicators such as C-reaction protein (CRP) (SMD = −1.67, 95% CI: −2.43 to −0.90, P < 0.0001).…”

Image_2_Phosphorylation of Dynamin-Related Protein 1 (DRP1) Regulates Mitochondrial Dynamics and Skeletal Muscle Wasting in Cancer Cachexia.TIF by Xiangyu Mao (5688623)

“…A cachexia model in vitro was established via coculturing a C2C12 myotube with media from C26 colon cancer cells. …”

Table_3_Cymbopogon citratus (DC.) Stapf aqueous extract ameliorates loperamide-induced constipation in mice by promoting gastrointestinal motility and regulating the gut microbiota... by Xiaoyu Gao (391492)

“…Importantly, we established a complex but clear network between gut microbiota and host parameters. …”

Image_6_Cymbopogon citratus (DC.) Stapf aqueous extract ameliorates loperamide-induced constipation in mice by promoting gastrointestinal motility and regulating the gut microbiota... by Xiaoyu Gao (391492)

“…Importantly, we established a complex but clear network between gut microbiota and host parameters. …”

Image_1_Cymbopogon citratus (DC.) Stapf aqueous extract ameliorates loperamide-induced constipation in mice by promoting gastrointestinal motility and regulating the gut microbiota... by Xiaoyu Gao (391492)

“…Importantly, we established a complex but clear network between gut microbiota and host parameters. …”

Image_2_Cymbopogon citratus (DC.) Stapf aqueous extract ameliorates loperamide-induced constipation in mice by promoting gastrointestinal motility and regulating the gut microbiota... by Xiaoyu Gao (391492)

“…Importantly, we established a complex but clear network between gut microbiota and host parameters. …”