Image13_Valsartan attenuates LPS-induced ALI by modulating NF-κB and MAPK pathways.TIF by Mi Zhou (9884)

“…</p><p>Results: Valsartan rescued LPS-reduced cell viability of BEAS-2B cells, improved the pulmonary function, ameliorated pathological lung injury in mice with ALI, ameliorated LPS-induced neutrophil recruitment in BALF and lung tissue of mice, attenuated oxidative stress by increasing the level of SOD and decreasing that of MDA and GSSG, inhibited LPS-induced MUC5AC overproduction, decreased the LPS-induced increase in expression of pro-inflammatory cytokines/chemokines including TNF-α, IL-6, IL-1β, CXCL-1 and CXCL-2, and restored the expression of anti-inflammatory IL-10. …”

Image4_Valsartan attenuates LPS-induced ALI by modulating NF-κB and MAPK pathways.TIF by Mi Zhou (9884)

“…</p><p>Results: Valsartan rescued LPS-reduced cell viability of BEAS-2B cells, improved the pulmonary function, ameliorated pathological lung injury in mice with ALI, ameliorated LPS-induced neutrophil recruitment in BALF and lung tissue of mice, attenuated oxidative stress by increasing the level of SOD and decreasing that of MDA and GSSG, inhibited LPS-induced MUC5AC overproduction, decreased the LPS-induced increase in expression of pro-inflammatory cytokines/chemokines including TNF-α, IL-6, IL-1β, CXCL-1 and CXCL-2, and restored the expression of anti-inflammatory IL-10. …”

Image2_Valsartan attenuates LPS-induced ALI by modulating NF-κB and MAPK pathways.TIF by Mi Zhou (9884)

“…</p><p>Results: Valsartan rescued LPS-reduced cell viability of BEAS-2B cells, improved the pulmonary function, ameliorated pathological lung injury in mice with ALI, ameliorated LPS-induced neutrophil recruitment in BALF and lung tissue of mice, attenuated oxidative stress by increasing the level of SOD and decreasing that of MDA and GSSG, inhibited LPS-induced MUC5AC overproduction, decreased the LPS-induced increase in expression of pro-inflammatory cytokines/chemokines including TNF-α, IL-6, IL-1β, CXCL-1 and CXCL-2, and restored the expression of anti-inflammatory IL-10. …”

Image8_Valsartan attenuates LPS-induced ALI by modulating NF-κB and MAPK pathways.TIF by Mi Zhou (9884)

“…</p><p>Results: Valsartan rescued LPS-reduced cell viability of BEAS-2B cells, improved the pulmonary function, ameliorated pathological lung injury in mice with ALI, ameliorated LPS-induced neutrophil recruitment in BALF and lung tissue of mice, attenuated oxidative stress by increasing the level of SOD and decreasing that of MDA and GSSG, inhibited LPS-induced MUC5AC overproduction, decreased the LPS-induced increase in expression of pro-inflammatory cytokines/chemokines including TNF-α, IL-6, IL-1β, CXCL-1 and CXCL-2, and restored the expression of anti-inflammatory IL-10. …”

Image9_Valsartan attenuates LPS-induced ALI by modulating NF-κB and MAPK pathways.TIF by Mi Zhou (9884)

“…</p><p>Results: Valsartan rescued LPS-reduced cell viability of BEAS-2B cells, improved the pulmonary function, ameliorated pathological lung injury in mice with ALI, ameliorated LPS-induced neutrophil recruitment in BALF and lung tissue of mice, attenuated oxidative stress by increasing the level of SOD and decreasing that of MDA and GSSG, inhibited LPS-induced MUC5AC overproduction, decreased the LPS-induced increase in expression of pro-inflammatory cytokines/chemokines including TNF-α, IL-6, IL-1β, CXCL-1 and CXCL-2, and restored the expression of anti-inflammatory IL-10. …”

Image6_Valsartan attenuates LPS-induced ALI by modulating NF-κB and MAPK pathways.TIF by Mi Zhou (9884)

“…</p><p>Results: Valsartan rescued LPS-reduced cell viability of BEAS-2B cells, improved the pulmonary function, ameliorated pathological lung injury in mice with ALI, ameliorated LPS-induced neutrophil recruitment in BALF and lung tissue of mice, attenuated oxidative stress by increasing the level of SOD and decreasing that of MDA and GSSG, inhibited LPS-induced MUC5AC overproduction, decreased the LPS-induced increase in expression of pro-inflammatory cytokines/chemokines including TNF-α, IL-6, IL-1β, CXCL-1 and CXCL-2, and restored the expression of anti-inflammatory IL-10. …”

Image11_Valsartan attenuates LPS-induced ALI by modulating NF-κB and MAPK pathways.TIF by Mi Zhou (9884)

“…</p><p>Results: Valsartan rescued LPS-reduced cell viability of BEAS-2B cells, improved the pulmonary function, ameliorated pathological lung injury in mice with ALI, ameliorated LPS-induced neutrophil recruitment in BALF and lung tissue of mice, attenuated oxidative stress by increasing the level of SOD and decreasing that of MDA and GSSG, inhibited LPS-induced MUC5AC overproduction, decreased the LPS-induced increase in expression of pro-inflammatory cytokines/chemokines including TNF-α, IL-6, IL-1β, CXCL-1 and CXCL-2, and restored the expression of anti-inflammatory IL-10. …”

Effects of speed on pheasant gaits and hindlimb joint angles: Supplementary material by Rui Zhang (13940)

“…The duty factor also decreased, but was less than 0.5 in only about 10% of measurements. …”

Relationship between increased cingulo-opercular/salience network integration and cognitive control. by Scott Marek (841529)

“…<p>Performance on the antisaccade task improves throughout adolescence, evidenced by increased accuracy (A) and decreased reaction time (B). As integration of the CO/Salience network increases, reaction time significantly decreases (C). …”

Chronic CSE treatment increased ROS, increasing PDK2 expression, resulting in enhanced HIF1α expression. by Wenyue Sun (134001)

“…<p>A, ROS activity was measured in triplicate with the intensity shift from a mean of 74.2 in the control cells (light gray) to a mean of 102.6 in the CSE treated OKF6 cells (dark gary) (n = 3, P<0.05) by flow cytometry. …”

Safranin O-stained sections of femoral condyle. by Luning Wang (769124)

“…Decreased staining in the chondronecrosis shows a variable degree of pallor. …”

High 22G RNA levels are associated with low mRNA expression, compatible with silencing. by Alexandra Bezler (6316151)

“…<p>A) Mean normalized mRNA [<a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1007905#pgen.1007905.ref055" target="_blank">55</a>] and 22G RNA reads detected in hermaphrodite and male gonads (data in 20 bins according to 22G RNA level; number of genes per bin: 4–1101 in hermaphrodites, 5–1343 in males; mean: solid line, outliers: circles). mRNA expression is globally decreased for the top 5% of genes (shaded area) with high levels of 22G RNA. …”

Relative risks of the new mutations with regards to known RAMs on the African dataset. by Luc Blassel (11337937)

“…<p>(i.e. the prevalence of the new mutation in sequences with a given RAM divided by the prevalence of the new mutation in sequences without the RAM). …”

Additional file 1 of Effects of characteristic parameters on surface seismic aggravation in 2D sedimentary valley by Shengyin Qiang (12572941)

“…<p>Compared the Fourier amplitude spectra of the observed and simulated time series (Figure 4) at these stations from the 13 May 1995 earthquake, similar spectral values were amplified within the effective frequency band of the simulation while rapidly decreasing for more than 7hz.   The 5% damped normalized acceleration response spectra of the selected strong-motion recordings. …”

Effects of astragaloside IV on mRNA expressions of neuroinflammatory biomarkers and anti-oxidative enzymes. by Yixin He (466799)

“…<p>A, ASI decreased GFAP mRNA expression in cortices of EAE mice. …”

Numerical investigation of steady air injection flow to control rotating stall in centrifugal compressors by Halawa, Taher

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In-vitro evaluation of physiological changes caused by iron oxide nanoparticles in <i>Solanum villosum</i> by Mina Ghaseminezhad (11606128)

“…<p>Application of iron nanoparticles as iron fertilizer can be a functional strategy to manage iron deficiency in agricultural crops. …”

Table_1_Iron- and Zinc-Fortified Lentil (Lens culinaris Medik.) Demonstrate Enhanced and Stable Iron Bioavailability After Storage.DOCX by Rajib Podder (6661112)

“…Fe, Zn, and RFeB% increased significantly in two batches of samples from the three LPTs, and decreased by 5–15% after 1 year of storage. PA concentration decreased from 8 to 15% after fortification of all samples from two batches of the three LPTs but showed different patterns of influence after storage. …”

DataSheet_1_Novel Compound C150 Inhibits Pancreatic Cancer Cell Epithelial-to-Mesenchymal Transition and Tumor Growth in Mice.pdf by Tao Wang (12008)

“…C150 inhibited cell proliferation in multiple pancreatic cancer cells with IC₅₀ values of 1-2.5 μM, while in an non-cancerous pancreatic epithelial cell line hTERT-HPNE the IC₅₀ value was >12.5 μM. …”

Table_3_Iron- and Zinc-Fortified Lentil (Lens culinaris Medik.) Demonstrate Enhanced and Stable Iron Bioavailability After Storage.DOCX by Rajib Podder (6661112)

“…Fe, Zn, and RFeB% increased significantly in two batches of samples from the three LPTs, and decreased by 5–15% after 1 year of storage. PA concentration decreased from 8 to 15% after fortification of all samples from two batches of the three LPTs but showed different patterns of influence after storage. …”