Hypoxia down-regulates Wnt/β-catenin signaling in human OS cells. by Donald J. Scholten II (649432)

“…B, Axin2 mRNA levels were determined as a measure of Wnt/β-catenin signaling under hypoxic conditions (72 hour, 0.5% O₂) via quantitative reverse-transcription PCR (qrt-PCR) normalized to normoxia. …”

The expression level of Bcl-xL is increased in chemoresistant cells and its suppression reduces carboplatin resistance. by Natini Jinawath (247165)

“…B and C) Knockdown effect of Bcl-xL shRNA in SKOV3-CR cells (B) and in A2780-CR cells (C). After transfection with Bcl-xL shRNA and selection with puromycin for 5–7 days, Bcl-xL expression level decreases (left panels). …”

Lung histology analysis. by Carolin Boehne (10531245)

“…<p>(A-D) Lungs were stained for eosinophilic lung inflammation (H&E, A) or mucus secretion (PAS, C), followed by computer-based quantification using an image analyzing program (B and D). …”

Sustained Effects of Developmental Exposure to Ethanol on Zebrafish Anxiety-Like Behaviour by Matteo Baiamonte (721514)

“…(A-D) Developmental ethanol exposure decreased thigmotaxis at both 9dpf (A,B: <i>F</i> 2,105 = 4.76, <i>P</i><0.05) and 10dpf (C,D: <i>F</i> 2, 285 = 6.69, <i>P</i><0.05), with the greatest difference between 20mM ethanol treatment and the control. …”

Regulation of cytoprotective gene activation is required for xenobiotic stress tolerance. by David E. Shore (123998)

“…Animals were raised to day 3 adulthood on solid media and transferred to solution containing sublethal (∼LD30) treatments of 24 mg/ml paraquat (A), 22 µg/ml sodium azide (B), 5.2 mg/ml cadmium chloride (C), 696 µg/ml antimycin (D) or solvent alone (<a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1002792#pgen.1002792.s004" target="_blank">Figure S4</a>). …”

Spatial distribution of interactions. by Evlyn Pless (822892)

“…The left figure of each pair shows interactions at the very beginning of an experiment that decreased the rate of incoming foragers, and the right figure shows interactions 3–5 minutes after the experiment was complete. …”

Mice with metastatic lung cancer develop anemia with reticulocytosis. by Airie Kim (544745)

“…Compared to controls, the tumor-bearing mice have: (A) decreased hemoglobin; (B) increased reticulocytosis. …”

Boxplots corresponding to Fig 7. by Lianna Zhao (18239240)

“…Furthermore, when mask-wearing compliance reaches 80%, the maximum infection rate significantly decreases to approximately 5%.</p>…”

Effect of z-FA-FMK and other peptidyl methylketones on primary T cell proliferation. by Tanuja Rajah (730555)

“…<p>PBMCs (1 x 10⁶/ml) were stimulated with anti-CD3 (5 μg/ml) in the presence of various concentrations of z-FA-FMK analogues (A), different peptidyl FMKs (B), or different N-terminal groups (C) for 72 h. …”

ADMIXTURE groups using altered clonal cluster frequencies. by Manuela Carrasquilla (2897933)

“…This analysis best supports a division into five groups (<i>K</i> = 5), of which only two fully match with the original analysis. …”

Data_Sheet_1_Insulin Modulates the Immune Cell Phenotype in Pulmonary Allergic Inflammation and Increases Pulmonary Resistance in Diabetic Mice.pdf by Sabrina S. Ferreira (8432574)

“…</p><p>Materials and Methods: To evaluate the effects of relative insulin deficiency, an experimental model of diabetes was induced by a single dose of alloxan (50 mg/kg, i.v.). After 10 days, the mice were sensitized with ovalbumin [OVA, 20 μg and 2 mg of Al(OH)₃, i.p.]. …”

The effect of ZAP-S on L1 RNA and L1 protein expression. by John B. Moldovan (240328)

“…<p><i>(A) Schematic of pJM101/L1</i>.<i>3Δneo</i>: Bold black lines indicate the approximate location of probes (5UTR99 and ORF2_5804) used in the northern blot experiments. pJM101/L1.3Δneo is expressed from a pCEP4 vector. …”

Capsid stability can be affected by heat or CA mutations. by Tiana M. Scott (13825069)

“…Heat treatment slightly decreased the ability of plasmid DNA to activate cGAS (possibly through partial denaturation and/or aggregation of the DNA into a less accessible structure). …”

Evaluation and prediction of fish aesthetic values. by Juliette Langlois (12822131)

“…<p>(a) Workflow of the online survey and deep learning prediction of aesthetic values. (1) Pairs of images were presented to the public during the online survey and scored using the Elo algorithm (see <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3001640#sec010" target="_blank">Methods</a>). …”

Video_1_Aging dysregulates neutrophil extracellular trap formation in response to HIV in blood and genital tissues.mp4 by Laura Moreno de Lara (12966254)

“…However, how NET formation is triggered by HIV in different tissues and whether this mechanism is affected by aging remain unknown. We demonstrate that the mechanisms that trigger NET release in response to HIV are different in blood and genital tissues, and that NET release decreases with aging. …”

Video_4_Aging dysregulates neutrophil extracellular trap formation in response to HIV in blood and genital tissues.mp4 by Laura Moreno de Lara (12966254)

“…However, how NET formation is triggered by HIV in different tissues and whether this mechanism is affected by aging remain unknown. We demonstrate that the mechanisms that trigger NET release in response to HIV are different in blood and genital tissues, and that NET release decreases with aging. …”

Video_6_Aging dysregulates neutrophil extracellular trap formation in response to HIV in blood and genital tissues.mp4 by Laura Moreno de Lara (12966254)

“…However, how NET formation is triggered by HIV in different tissues and whether this mechanism is affected by aging remain unknown. We demonstrate that the mechanisms that trigger NET release in response to HIV are different in blood and genital tissues, and that NET release decreases with aging. …”

Video_3_Aging dysregulates neutrophil extracellular trap formation in response to HIV in blood and genital tissues.mp4 by Laura Moreno de Lara (12966254)

“…However, how NET formation is triggered by HIV in different tissues and whether this mechanism is affected by aging remain unknown. We demonstrate that the mechanisms that trigger NET release in response to HIV are different in blood and genital tissues, and that NET release decreases with aging. …”

Video_2_Aging dysregulates neutrophil extracellular trap formation in response to HIV in blood and genital tissues.mp4 by Laura Moreno de Lara (12966254)

“…However, how NET formation is triggered by HIV in different tissues and whether this mechanism is affected by aging remain unknown. We demonstrate that the mechanisms that trigger NET release in response to HIV are different in blood and genital tissues, and that NET release decreases with aging. …”

DataSheet_1_Aging dysregulates neutrophil extracellular trap formation in response to HIV in blood and genital tissues.docx by Laura Moreno de Lara (12966254)

“…However, how NET formation is triggered by HIV in different tissues and whether this mechanism is affected by aging remain unknown. We demonstrate that the mechanisms that trigger NET release in response to HIV are different in blood and genital tissues, and that NET release decreases with aging. …”