Negative regulation of Tkv protein level by S6KL via proteasomal degradation pathway. by Guoli Zhao (699622)

“…Actin was used as a loading control. (D) Tkv protein level was increased in S2 cells expressing a reduced level of S6KL. …”

Socio-behavioral risk factors among older adults living with HIV in Thailand by Patou Masika Musumari (509494)

“…<div><p>Background</p><p>There has been a global increase in HIV infection in persons 50 years of age and older. …”

Table_1_Work-related injuries of rehabilitation therapists and measures for prevention.DOCX by Wei Liu (20030)

“…Specifically, neuro-physiotherapists (OR [95% CI]: 3.04 [1.56–5.92]), musculoskeletal physiotherapists (OR [95% CI]: 2.46 [1.16–5.18]), and intensive care physiotherapists (OR [95% CI]: 4.70 [1.24–17.88]) were at higher risk. …”

Image 1_Exploring the role of mitochondrial metabolism and immune infiltration in myocardial infarction: novel insights from bioinformatics and experimental validation.tif by Jingyi Hou (698975)

“…This study aimed to clarify the roles of mitochondrial metabolism and immune infiltration in MI, using a combination of bioinformatics analyses and experimental validation.…”

Protective Effects of Triphala on Dermal Fibroblasts and Human Keratinocytes by Sandeep R. Varma (843403)

“…TE increased collagen-I, involucrin and filaggrin synthesis by 70.72 ± 2.3%, 67.61 ± 2.1% and 51.91 ± 3.5% in HDF or HaCaT cells respectively. TE also exhibited anti-tyrosinase and melanin inhibition properties in a dose-dependent manner. …”

Image1_Jia-Wei-Yu-Ping-Feng-San Attenuates Group 2 Innate Lymphoid Cell-Mediated Airway Inflammation in Allergic Asthma.JPEG by Lingna Xue (11101695)

“…Jia-Wei-Yu-Ping-Feng-San (JWYPFS), a traditional Chinese medicine, has been widely used to treat asthma in China. …”

RNA-Seq Transcriptomic Responses of Full-Thickness Dermal Excision Wounds to <i>Pseudomonas aeruginosa</i> Acute and Biofilm Infection by S. L. Rajasekhar Karna (320813)

“…Additionally, the raw counts of multiple types of differentially-expressed ncRNAs increased on post-wounding day 3 in control wounds, but infection suppressed this increase. After 5 and 9 days, these ncRNA counts in control wounds decreased, whereas they increased in the infected, healing-impaired wounds. …”

DataSheet_1_Body composition and inflammation variables as the potential prognostic factors in epithelial ovarian cancer treated with Olaparib.pdf by Xingzi Guo (18440394)

“…</p>Results<p>The median follow-up duration was 16 months (range: 5-49 months). Survival analysis indicated that high SATI, high VATI, high SMI, high BMD, low NLR, and low PLR were associated with decreased risk of disease progression (all p < 0.05). …”

Image1_Bifidobacterium longum CECT 7894 Improves the Efficacy of Infliximab for DSS-Induced Colitis via Regulating the Gut Microbiota and Bile Acid Metabolism.TIF by Fangfei Xiao (11951737)

“…</p><p>Methods: C57BL/6 mice were treated with phosphate-buffered saline (PBS) or B. longum CECT 7894 (5 × 10⁸ CFU/day) once daily by gavage for 5 days and subsequently induced acute colitis by 3% (w/v) DSS in drinking water. …”

Hyperhidrosis Prevalence and Demographical Characteristics in Dermatology Outpatients in Shanghai and Vancouver by Yudan Liu (2623240)

“…Primary HH has highest prevalence in those younger than 30 years of age, decreasing dramatically in later years. Caucasian subjects are at least 2.5 times more likely to develop axillary hyperhidrosis compared to Chinese subjects. …”

Functional <i>IL6R</i> 358Ala Allele Impairs Classical IL-6 Receptor Signaling and Influences Risk of Diverse Inflammatory Diseases by Ricardo C. Ferreira (174523)

“…We demonstrate that, although 358Ala increases transcription of the soluble <i>IL6R</i> isoform (<i>P</i> = 8.3×10⁻²²) and not the membrane-bound isoform, 358Ala reduces surface expression of IL-6R on CD4+ T cells and monocytes (up to 28% reduction per allele; <i>P</i>≤5.6×10⁻²²). Importantly, reduced expression of membrane-bound IL-6R resulted in impaired IL-6 responsiveness, as measured by decreased phosphorylation of the transcription factors STAT3 and STAT1 following stimulation with IL-6 (<i>P</i>≤5.2×10⁻⁷). …”

Table 1_Protocatechuic aldehyde ameliorates high glucose-induced podocyte injury by attenuating inflammation, oxidative stress, and apoptosis via suppression of endoplasmic reticul... by Yishu Wang (845334)

“…</p>Objective<p>To investigate the effects and mechanism of PCA on high glucose-induced podocyte inflammation, oxidative stress, and apoptotic injury.</p>Methods<p>A podocyte injury model was established by treating mouse podocytes (MPC5) with high-glucose medium. …”

Cell death induced by LY2090314 is dependent on β-catenin and GSK3β knockdown increases the sensitivity of cells to LY2090314. by Jennifer M. Atkinson (730576)

“…<p><b>A</b>. Melanoma cells stably transfected with shRNAs targeting β-catenin display decreased β-catenin and Axin2 protein expression by western blot. …”

Gene expression profiles of the <i>Cyp1b1</i>+/+ and <i>Cyp1b1</i>-/- retinal AC. by Juliana Falero-Perez (5905103)

“…Red indicates increased expression and green indicates decreased expression. The DEG were defined as having absolute FC> 1.5 and an FDR< 0.05.…”

The detection of cryptic <i>Plasmodium</i> infection among villagers in Attapeu province, Lao PDR by Moritoshi Iwagami (327464)

“…Among the 47 participants with parasitemia, only one had a fever (≥37.5°C) and 31 (66.0%) were adult males. …”

The Visibility of Disabilities within Pharmacy Program Recruitment Material. by Hussain, Farhat Naz

“…Targeted recruitment of students with disabilities is a novel area in pharmacy education and may help to attract qualified students in light of decreasing applicant numbers. …”
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Influence of TnI affinity for actin and TnC on muscle cooperativity. by Sander Land (782066)

“…Panel B shows calcium sensitivity, which follows a smooth gradient The yellow ‘X’ indicates our choice of parameters, and the red contours indicate the regions within which <i>n</i>_<i>H</i> ≥ 5. …”

Single cell statistics in low and high synaptic input states. by Ashok Litwin-Kumar (135071)

“…Excitatory inputs occurred at a rate of 1.5 kHz in the low state and 6.2 kHz in the high state, modeling the activity from a pool of pre-synaptic cells. …”

Temporal development of microhemorrhages in the CNS. by Angelika Hoffmann (849337)

“…<p>Mice (<i>n</i> = 5) were exposed to 48 h of normobaric hypoxia (8% oxygen) followed by rapid reoxygenation and exposure to normoxic conditions (~21% oxygen) for 24 h. …”

The prevalence of burnout syndrome in medical students by Gilson de Cavalcante Almeida (10384170)

“…Two groups – burnout/risk and non-burnout – were compared using the chi-square and likelihood ratio tests with a significance level of 5%. Variables with p < 0.20 were included in a multivariate analysis logistical regression model. …”