Sustained increase in the levels of pro-inflammatory cytokine and chemokine in the testis correlate with systemic inflammation. by Stefanos Giannakopoulos (15628394)

“…The statistical significance (*p<0.05, **p<0.01, ***< p<0.001) was determined using Mann-Whitney test for all analyses <b>(C)</b> Pearson’s correlation coefficient analysis between testicular defects (cells in lumen, lack of lumen, and lamina separation) and key cytokines (red box) and chemokines (yellow box) in the serum (left) and testis (right) at D3, D5, and D8. Pearson coefficient >0.6 was considered a significant correlation.…”

Video2_Novel Biallelic Variant in the BRAT1 Gene Caused Nonprogressive Cerebellar Ataxia Syndrome.MP4 by Yiming Qi (780014)

“…Here, we reported a 10-year-old girl with severe intellectual disability, rigidity, ataxia or dyspraxia, and cerebellar atrophy on brain MRI; two BRAT1 variants in the trans configuration [c.1014A > C (p.Pro338 = ); c.706delC (p.Leu236Cysfs*5)] were detected using whole-exome sequencing. …”

Aptamer-Based Polyvalent Ligands for Regulated Cell Attachment on the Hydrogel Surface by Erin R. Gaddes (1398304)

Transcriptome analysis revealing molecular mechanisms of enhanced pigment yield by succinic acid and fluconazole by Jie Qiao (120356)

“…The pigment yield was significantly improved by adding 0.35 g·L⁻¹ succinic acid or 1.5 g·L⁻¹ fluconazole. Transcriptome sequencing and RT-qPCR confirmation were performed to reveal transcriptome changes. …”

Image_2_Case Report: Low-Dose Apatinib in the Treatment of Intrahepatic Biliary Cystadenoma With Recurrence and Malignant Transformation.tif by Yongguang Yang (3144873)

“…Regular re-examination showed that the tumor had significantly decreased in size. On January 16, 2021, a CT scan revealed a tumor diameter of 4.5 cm. …”

QKI-7 Regulates Expression of Interferon-Related Genes in Human Astrocyte Glioma Cells by Lin Jiang (217766)

“…<div><h3>Background</h3><p>The human QKI gene, called <em>quaking homolog</em>, <em>KH domain RNA binding (mouse)</em>, is a candidate gene for schizophrenia encoding an RNA-binding protein. …”

PCR validation of ionizing radiation responsive genes in LCLs. by Carl N. Sprung (106851)

“…(D) Example of individual cell lines that show increased or decreased expression at a specific PSR following radiation are shown. …”

Video3_Novel Biallelic Variant in the BRAT1 Gene Caused Nonprogressive Cerebellar Ataxia Syndrome.MP4 by Yiming Qi (780014)

“…Here, we reported a 10-year-old girl with severe intellectual disability, rigidity, ataxia or dyspraxia, and cerebellar atrophy on brain MRI; two BRAT1 variants in the trans configuration [c.1014A > C (p.Pro338 = ); c.706delC (p.Leu236Cysfs*5)] were detected using whole-exome sequencing. …”

Functional Characterization of AbeD, an RND-Type Membrane Transporter in Antimicrobial Resistance in <i>Acinetobacter baumannii</i> by Vijaya Bharathi Srinivasan (148478)

“…</p><p>Results</p><p>The <i>abeD</i> mutant displayed ~ 3.37 fold decreased survival and >5-fold reduced growth in hostile osmotic (0.25 M; NaCl) and oxidative (2.631 μM–6.574 μM; H₂O₂) stress conditions respectively. …”

Image_1_Differences in the Composition of Abundant Marine Picoeukaryotes in the Marginal Sea Derived from Flooding.jpeg by Chih-Ching Chung (12099041)

“…<p>The transient impact of flooding on the community composition of marine picoeukaryotes (PEs, cell size ≤5 μm) in the East China Sea (ECS) was revealed in this study. …”

Image_2_Netrin-1 Ameliorates Postoperative Delirium-Like Behavior in Aged Mice by Suppressing Neuroinflammation and Restoring Impaired Blood-Brain Barrier Permeability.TIF by Ke Li (106849)

“…We also assessed the reactive states of microglia and the permeability of the BBB by detecting cell junction proteins and the leakage of dextran. We found that a single dose of NTN-1 prophylaxis decreased the expression of IL-6 and HMGB-1 and upregulated the expression of IL-10 in the peripheral blood, hippocampus, and prefrontal cortex. …”

DataSheet1_Tomographic Image of Shear Wave Structure of NE India Based on Analysis of Rayleigh Wave Data.PDF by Amit Kumar (81180)

“…The images obtained reveal a very complicated tectonic regime. The Bengal Basin comprises a thick layer of sediments with the thickness increasing from west to east and a sudden steepening of the basement on the eastern side of the Eocene Hinge zone. …”

Table_2.docx by Sipla Aggarwal (4912828)

“…Four non-segregating RNAi lines of wheat were selected for detailed study (S3-D-6-1; S6-K-3-3; S6-K-6-10 and S16-D-9-5). Homozygous transgenic RNAi lines at T₄ seeds with a decreased transcript of TaIPK1 showed 28–56% reduction of the PA. …”

Table_2_Mortality Rate of Lymphoma in China, 2013–2020.docx by Weiping Liu (47182)

“…<p>Lymphoma is a malignant disease that threatens human health and imposes a significant burden on the society burden; however, there are limited accurate mortality data on lymphoma in China. …”

Image_1_Netrin-1 Ameliorates Postoperative Delirium-Like Behavior in Aged Mice by Suppressing Neuroinflammation and Restoring Impaired Blood-Brain Barrier Permeability.TIF by Ke Li (106849)

“…We also assessed the reactive states of microglia and the permeability of the BBB by detecting cell junction proteins and the leakage of dextran. We found that a single dose of NTN-1 prophylaxis decreased the expression of IL-6 and HMGB-1 and upregulated the expression of IL-10 in the peripheral blood, hippocampus, and prefrontal cortex. …”

DataSheet_1_Metabolome analysis reveals flavonoid changes during the leaf color transition in Populus × euramericana ‘Zhonghuahongye’.zip by Mengjiao Chen (6560651)

“…</p>Results<p>The a*, C* and chromatic light values of the leaves decreased by 108.91%, 52.08% and 113.34%, while the brightness L values and chromatic b* values gradually increased by 36.01% and 13.94%, respectively. …”

Supplementary Material for: Long-term Efficacy and Safety of Upacicalcet in Japanese Hemodialysis Patients with Secondary Hyperparathyroidism: Open-label 52-week Study by Hamano T. (2892236)

“…Introduction Upacicalcet is a novel injectable calcimimetic. This phase 3 multicenter open-label study aimed to assess the long-term efficacy and safety of upacicalcet in hemodialysis (HD) patients with secondary hyperparathyroidism (SHPT). …”

<b>Characterising the mechanics of </b><b>rectangular</b><b> peg-hole disassembly and the effect of </b><b>the position of the </b><b>active compliance centre on </b><b>the </b><b>... by Farzaneh Goli (17320060)

“…The contact conditions are categorised into five groups: 1) two-point contact, 2) two-sided contact, 3) combined two-sided and one-plane contact, 4) two-edge contact, and 5) three-edge contact. …”

Table_1_Target Body Temperature in Very Low Birth Weight Infants: Clinical Consensus in Place of Scientific Evidence.DOCX by Anna Perez (3471611)

“…Likewise, the cut-off points for hypo- and hyperthermia were defined very similarly and showed low inter-center variability. This is a remarkable finding in view of the fact that the body temperature of mammalian fetuses in utero is 0.5–1.0°C higher than that of the mother.…”

Plasma Protein Characteristics of Long-Term Hemodialysis Survivors by Yao-Ping Lin (114868)

“…Compared to the SHD, the LHD survivors had increased plasma vitamin D binding proteins (DBP) and decreased clusterin, apolipoprotein A-IV, haptoglobin, hemopexin, complement factors B and H, and altered isoforms of α1-antitrypsin and fibrinogen gamma. …”