Patterns of Gene and Metabolite Define the Effects of Extracellular Osmolality on Kidney Collecting Duct by Hyo-Jung Choi (317873)

“…Integrated analysis of the transcriptome and metabolome revealed that decreased extracellular osmolality was associated with decreased levels of organic osmolytes, glucose, intermediates of citric acid cycle, and branched-chain amino acids (BCAA) in IMCD cells, along with significantly decreased gene expression and protein abundance of P-type transporters (ATP1B1), ABC transporters (ABCC5 and ABCG1), and insulin signaling pathways (IRS2). …”

Patterns of Gene and Metabolite Define the Effects of Extracellular Osmolality on Kidney Collecting Duct by Hyo-Jung Choi (317873)

“…Integrated analysis of the transcriptome and metabolome revealed that decreased extracellular osmolality was associated with decreased levels of organic osmolytes, glucose, intermediates of citric acid cycle, and branched-chain amino acids (BCAA) in IMCD cells, along with significantly decreased gene expression and protein abundance of P-type transporters (ATP1B1), ABC transporters (ABCC5 and ABCG1), and insulin signaling pathways (IRS2). …”

Patterns of Gene and Metabolite Define the Effects of Extracellular Osmolality on Kidney Collecting Duct by Hyo-Jung Choi (317873)

“…Integrated analysis of the transcriptome and metabolome revealed that decreased extracellular osmolality was associated with decreased levels of organic osmolytes, glucose, intermediates of citric acid cycle, and branched-chain amino acids (BCAA) in IMCD cells, along with significantly decreased gene expression and protein abundance of P-type transporters (ATP1B1), ABC transporters (ABCC5 and ABCG1), and insulin signaling pathways (IRS2). …”

Patterns of Gene and Metabolite Define the Effects of Extracellular Osmolality on Kidney Collecting Duct by Hyo-Jung Choi (317873)

“…Integrated analysis of the transcriptome and metabolome revealed that decreased extracellular osmolality was associated with decreased levels of organic osmolytes, glucose, intermediates of citric acid cycle, and branched-chain amino acids (BCAA) in IMCD cells, along with significantly decreased gene expression and protein abundance of P-type transporters (ATP1B1), ABC transporters (ABCC5 and ABCG1), and insulin signaling pathways (IRS2). …”

Patterns of Gene and Metabolite Define the Effects of Extracellular Osmolality on Kidney Collecting Duct by Hyo-Jung Choi (317873)

“…Integrated analysis of the transcriptome and metabolome revealed that decreased extracellular osmolality was associated with decreased levels of organic osmolytes, glucose, intermediates of citric acid cycle, and branched-chain amino acids (BCAA) in IMCD cells, along with significantly decreased gene expression and protein abundance of P-type transporters (ATP1B1), ABC transporters (ABCC5 and ABCG1), and insulin signaling pathways (IRS2). …”

Variation of macroscale measurables with the activator production rate by Philip J. Murray (108828)

“…<p><b>.</b> (a) The times spent in anagen and refractory and competent telogen (calculated using <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1002804#pcbi.1002804.e092" target="_blank">equations (4)</a>, <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1002804#pcbi.1002804.e093" target="_blank">(5)</a> and <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1002804#pcbi.1002804.e107" target="_blank">(8)</a>) are plotted against . …”

Phase-response curves (PRCs) of the Morris-Lecar DS model for various <i>τ</i>_<i>δ</i> and <i>G</i>_in. Values of <i>G</i>_in and <i>τ</i><sub><i>δ</... by Robert P. Gowers (8735679)

“…When ( ms), increasing <i>G</i>_in switches the onset PRC shape first from a symmetric SNIC PRC (<b>A</b>) to an asymmetric HOM PRC (<b>B-C</b>), and later to a Hopf-like PRC (<b>D</b>). …”

Integrating expression data, regulatory motif conservation and protein–DNA binding information by Christopher E. Hart (8187)

“…In each heat-map genes are ordered by decreasing MCS score. Significant correlation can be seen between a high MCS score, protein–DNA binding and the expected expression pattern.…”

<i>dPRPS</i> mutants have lysosomal dysfunction. by Keemo Delos Santos (7349087)

“…Statistical testing in 5A-C were performed using One-way ANOVA where ns = p>0.05; *** = p ≤ 0.001; **** = p≤ 0.0001. …”

Data analysis: R code by Shantelle Claassen-Weitz (17117284)

“…Age was borderline significant at a 5% level (p = 0.0556). Most willing stool donors indicated that donating stool samples would not affect blood donations (140/157, 90%). …”

Phylogenetic Characterization of Fecal Microbial Communities of Dogs Fed Diets with or without Supplemental Dietary Fiber Using 454 Pyrosequencing by Ingmar S. Middelbos (251387)

“…</p><h3>Principal Findings</h3><p>Six healthy adult dogs were used in a crossover design. A control diet without supplemental fiber and a beet pulp-supplemented (7.5%) diet were fed. …”

Data_Sheet_1_Arousal system stimulation and anesthetic state alter visuoparietal connectivity.PDF by Axel Hutt (3138303)

“…Local field potentials (LFPs) recorded previously in the secondary visual cortex (V2) and the adjacent parietal association cortex (PtA) in chronically instrumented unrestrained rats. …”

Thyroid Hormone Regulation of Gene Expression in Primary Cerebrocortical Cells: Role of Thyroid Hormone Receptor Subtypes and Interactions with Retinoic Acid and Glucocorticoids by Pilar Gil-Ibáñez (533517)

“…T3 had opposing influences on retinoic acid synthesizing enzymes, increasing the expression of <i>Aldh1a1</i>, and decreasing <i>Aldh1a3</i>, while increasing the retinoic acid degrading enzyme <i>Cyp26b1</i>. …”

SupplementaryData6.PPT by Elena Silvestri (354706)

“…The administration of the naturally occurring metabolite 3,5-diiodo-L-thyronine (T2) with thyromimetic actions to high fat diet (HFD)-fed rats exerts a systemic hypolipidemic effect, which produces a lack of IMCL accumulation, a shift toward glycolytic fibers and amelioration of insulin sensitivity in gastrocnemius muscle. …”

Tuning the Li Diffusivity of Poor Ionic Conductors by Mechanical Treatment: High Li Conductivity of Strongly Defective LiTaO₃ Nanoparticles by M. Wilkening (2139364)

“…The activation energy <i>E</i>_A is reduced by about one-third, i.e., it decreased from <i>E</i>_A = 0.90(1) eV to about <i>E</i>_A = 0.63(1) eV. …”

SupplementaryData3.XLS by Elena Silvestri (354706)

“…The administration of the naturally occurring metabolite 3,5-diiodo-L-thyronine (T2) with thyromimetic actions to high fat diet (HFD)-fed rats exerts a systemic hypolipidemic effect, which produces a lack of IMCL accumulation, a shift toward glycolytic fibers and amelioration of insulin sensitivity in gastrocnemius muscle. …”

Data_Sheet_1_Characterization of the Microbiome at the World’s Largest Potable Water Reuse Facility.docx by Blake W. Stamps (529622)

“…The Orange County Water District (OCWD) Advanced Water Purification Facility (AWPF) is a highly engineered system designed to treat and produce up to 100 million gallons per day (MGD) of purified water from a municipal wastewater source for potable reuse. …”

Onset of an epileptic seizure in the Stuart-Landau-like neurons population and the outcome of the controlled system. by Malbor Asllani (5537012)

“…Once the coupling parameter decreases and fluctuates again around a small value, 0.1, both systems recover the same non-synchronised state (data not shown).…”

Quantum Chemistry for Solvated Molecules on Graphical Processing Units Using Polarizable Continuum Models by Fang Liu (13271)

Transforming Small-Molecule Nanoaggregation into Functional Drug Delivery Platforms by JunHyuk Kim (21235657)