The <i>PIGA</i>c.1234C>T mutation increases <i>PIGA</i> function compared to <i>PIGA</i>null hiPSCs. by Xuan Yuan (225365)

“…Intensity of Smad 1/5/8 phosphorylation was comparably increased following BMP4 induction in both of PIGA<i>wt</i> hiPSCs and <i>PIGA</i>c.1234C>T hiPSCs; decreased responsiveness to BMP4 induction was observed in <i>PIGA</i>null hiPSCs as previously described. β -actin was used as an internal control.…”

Image_4_Global disease burden linked to diet high in red meat and colorectal cancer from 1990 to 2019 and its prediction up to 2030.JPEG by Xuesong Yang (175061)

“…However, there has been a lack of detailed understanding regarding the disease burden linked to diet high in red meat and CRC.…”

Image_8_Global disease burden linked to diet high in red meat and colorectal cancer from 1990 to 2019 and its prediction up to 2030.JPEG by Xuesong Yang (175061)

“…However, there has been a lack of detailed understanding regarding the disease burden linked to diet high in red meat and CRC.…”

Image3_Myeloid-derived growth factor promotes M2 macrophage polarization and attenuates Sjögren’s syndrome via suppression of the CX3CL1/CX3CR1 axis.tif by Zi Yang (276531)

“…</p>Results<p>Treatment of NOD/LtJ mice with MYDGF alleviated pSS, as indicated by increased salivary flow rate, reduced lymphocyte infiltration, attenuated glandular inflammation, and enhanced AQP5 and NKCC1 expression. The gene expression levels of cytokines and chemokines, including Ccl12, Ccl3, Il1r1, Ccr2, Cx3cr1, Il7, Mmp2, Mmp14, Il1b, and Il7, significantly decreased after treatment with MYDGF, as determined by RNA sequencing. …”

Image4_Myeloid-derived growth factor promotes M2 macrophage polarization and attenuates Sjögren’s syndrome via suppression of the CX3CL1/CX3CR1 axis.tif by Zi Yang (276531)

“…</p>Results<p>Treatment of NOD/LtJ mice with MYDGF alleviated pSS, as indicated by increased salivary flow rate, reduced lymphocyte infiltration, attenuated glandular inflammation, and enhanced AQP5 and NKCC1 expression. The gene expression levels of cytokines and chemokines, including Ccl12, Ccl3, Il1r1, Ccr2, Cx3cr1, Il7, Mmp2, Mmp14, Il1b, and Il7, significantly decreased after treatment with MYDGF, as determined by RNA sequencing. …”

Stabilization of Coordinated Carbonate in Aqueous Acidic Solution:  Steric Inhibition of Protonation in Co(III) Complexes Containing Chelated Carbonate^† by Sarah E. Cheyne (2647126)

“…The synthesis, characterization, X-ray crystal structures, and reactivity in aqueous acidic solution of the Co(III) carbonate complexes [Co(tpa)(O₂CO)]ClO₄·H₂O, [Co(Me-tpa)(O₂CO)]ClO₄·0.5H₂O, [Co(Me₂-tpa)(O₂CO)]ClO₄·0.5H₂O, and [Co(Me₃-tpa)(O₂CO)]ClO₄ are reported (tpa = tris(2-pyridylmethyl)amine; Me-tpa, Me₂-tpa, and Me₃-tpa are derivatives of tpa containing one, two, and three 6-methylpyridyl rings, respectively). …”

DataSheet1_C1q/TNF-Related Protein 9 Attenuates Atherosclerosis by Inhibiting Hyperglycemia-Induced Endothelial Cell Senescence Through the AMPKα/KLF4 Signaling Pathway.docx by Gang Wang (36685)

“…Human umbilical vein endothelial cells (HUVECs) were cultured in normal glucose (5.5 mM) and high glucose (40 mM) with or without recombinant human CTRP9 protein (3 μg/ml) for 48 h. …”

Image2_Myeloid-derived growth factor promotes M2 macrophage polarization and attenuates Sjögren’s syndrome via suppression of the CX3CL1/CX3CR1 axis.tif by Zi Yang (276531)

“…</p>Results<p>Treatment of NOD/LtJ mice with MYDGF alleviated pSS, as indicated by increased salivary flow rate, reduced lymphocyte infiltration, attenuated glandular inflammation, and enhanced AQP5 and NKCC1 expression. The gene expression levels of cytokines and chemokines, including Ccl12, Ccl3, Il1r1, Ccr2, Cx3cr1, Il7, Mmp2, Mmp14, Il1b, and Il7, significantly decreased after treatment with MYDGF, as determined by RNA sequencing. …”

Table1_Small-molecule BCL6 inhibitor protects chronic cardiac transplant rejection and inhibits T follicular helper cell expansion and humoral response.DOCX by Yuxuan Xia (14800378)

“…Splenocytes were collected at different time points after transplantation for CXCR5⁺PD-1⁺ and CXCR5⁺BCL6⁺ Tfh cells detection by flow cytometry (FCM). …”

Image_6_Global disease burden linked to diet high in red meat and colorectal cancer from 1990 to 2019 and its prediction up to 2030.JPEG by Xuesong Yang (175061)

“…However, there has been a lack of detailed understanding regarding the disease burden linked to diet high in red meat and CRC.…”

Bee bread shows therapeutic and protective effects by alleviating inflammation, oxidative stress, and apoptosis on acetic acid-induced gastric ulcer in rats by Hatice Colak (20773009)

“…In BB-pretreated ulcer group, MPO-(saline\BB, 39.9±3.7 U/g;22.2±2.2 U/g), caspase-3 (0.40±0.07 ng/g;0.18±0.01 ng/g) and IFN-γ (15.46±1.76;9.51±1.95 ng/g) levels decreased and TNF-α (31.77±5.13;18.94±2.59 ng/g) reduced only in BB-treated ulcer group. …”

Image_2_Global disease burden linked to diet high in red meat and colorectal cancer from 1990 to 2019 and its prediction up to 2030.JPEG by Xuesong Yang (175061)

“…However, there has been a lack of detailed understanding regarding the disease burden linked to diet high in red meat and CRC.…”

Table_1_Optimal Strategy for Antiplatelet Therapy After Coronary Drug-Eluting Stent Implantation in High-Risk “TWILIGHT-like” Patients With Diabetes Mellitus.DOCX by Hao-Yu Wang (3043500)

“…Prolonged DAPT was also associated with a reduced risk of definite/probable stent thrombosis [0.2 vs. 0.7%; HR_IPTW: 0.258 (0.083–0.802)] and non-significantly lower rate of myocardial infarction [0.5 vs. 0.8%; HR_IPTW: 0.676 (0.275–1.661)]. …”

Embryos co-injected with APPb-MO and APPb mRNA rescued defective phenotypes of the Vp and VII and spinal cord nerve projections observed in APPb morphants. by Ping Song (169215)

“…(D) The morphants showed an identical defected phenotype on axonal outgrowth of Vp & VII neurons when co-injected with the translation-block MO (3 ng per embryo) of the APPb and the splice-block MO (6.5 ng per embryo) of the APPb at lower doses that did not produce a defective phenotype individually. …”

Image_7_Global disease burden linked to diet high in red meat and colorectal cancer from 1990 to 2019 and its prediction up to 2030.JPEG by Xuesong Yang (175061)

“…However, there has been a lack of detailed understanding regarding the disease burden linked to diet high in red meat and CRC.…”

Table 1_Assessment of various salt water stresses with mineralization on plant growth and antioxidants activity to regulate oxidative stress and ROS scavenging of halophyte ice pla... by Xinchao Ma (22249096)

“…Therefore, experiment consisted of seven different salt treatments CK: distilled water control; T1: saline-alkali solution of 5 g/L; T2: saline-alkali solution of 10 g/L; T3: saline-alkali solution of 15 g/L; T4: saline-alkali solution of 20 g/L; T5: saline-alkali solution of 25 g/L; T6: saline-alkali solution of 30 g/L. …”

Development of progressive cataract in <i>Epha2</i> knockout mice and characterization of spatial and temporal regulation of EPHA2 expression in the lens. by Gyungah Jun (28927)

“…(A) Cataracts were visible by gross inspection in homozygous <i>Epha2</i> knockout mice (<i>Epha2^−/−</i>) between 5 to 8 months of age, but not in heterozygous or wild type mice. …”

Effect of ryanodine on the sI_AHP measured at steady state in rat CA1 pyramidal neurons. by Angelo Tedoldi (6547616)

“…(<b>D)</b> Time course of action of ryanodine (10 μM) on the sI_AHP amplitude in the same cell as for the traces shown in panels <b>A-C</b>. <b>(E)</b> Summary bar diagram showing that ryanodine decreases the amplitude of the sI_AHP by 23.3 ± 3.7% (n = 5; P = 0.03). …”

Establishment and characterization of LNCaP-Med19-si/sc and PC3-Med19-si/sc cells. by Shengqiang Yu (243316)

“…<p>(A) After lentivirus infection and FACS sorting, the transduction efficiency was confirmed by determining the GFP expression in a fluorescent microscope. …”

Inhibiting IDO-1 with INCB24360 reduced the M1-like macrophage proportion in the RAW264.7 cells induced by IFN-γ. by Rong Ji (1496803)

“…<p><b>(A)</b> The typical morphology of RAW264.7 cells after treatment with IFN-γ, IFN-γ+1-MT and IFN-γ + INCB24360. …”