Supplementary Material for: Plasma Xanthine Oxidase Activity Is Predictive of Cardiovascular Disease in Patients with Chronic Kidney Disease, Independently of Uric Acid Levels by Gondouin B. (4157221)

“…Oxidative stress seems to play a pivotal role in this process, and purine metabolism may be involved in CKD-related oxidative stress. …”

DataSheet1_Glacier Runoff Variation Since 1981 in the Upper Naryn River Catchments, Central Tien Shan.zip by Tomas Saks (10861360)

“…The basins contain more than 1,000 glaciers, which cover a total area of 776 km². We model the mass balance and runoff contribution of all glaciers with a simplified energy balance melt model and distributed accumulation model driven by ERA5 LAND re-analysis data for the time period of 1981–2019. …”

Data Sheet 1_Shengxian decoction alleviates cyclophosphamide-induced immunosuppression via improving B cell-mediated immune responses.docx by Chengyu Yang (10223976)

“…Background<p>Chemotherapy is a prevalent and extensively utilized cancer treatment modality. …”

Table 3_Mechanism of Huaiqihuang (HQH) against cyclophosphamide (CYP)-induced hippocampal neurotoxicity based on network pharmacology, molecular docking and experimental verificati... by Yueming Zhang (790755)

“…</p>Conclusion<p>HQH mitigates CYP-induced hippocampal neurotoxicity by decreasing oxidative stress, and inflammation, with HSP90AA1 being a key target, providing a novel therapeutic strategy for chemotherapy-associated cognitive impairment.…”

Longitudinal HTA analysis and HIV-1 decay in blood plasma and CSF of neurologically symptomatic subjects. by Gretja Schnell (108583)

“…<p>(A) Longitudinal V4/V5 HTA analysis of HIV-1 in paired blood plasma and CSF samples from 1 subject with MCMD (subject 4013) and 7 subjects with HIV-associated dementia that were initiating HAART. …”

Table_1_Tongguan Capsule Mitigates Post-myocardial Infarction Remodeling by Promoting Autophagy and Inhibiting Apoptosis: Role of Sirt1.DOCX by Shuai Mao (1627021)

“…<p>Left ventricular (LV) adverse remodeling and the concomitant functional deterioration contributes to the poor prognosis of patients with myocardial infarction (MI). Thus, a more effective treatment strategy is needed. …”

Table 1_Mechanism of Huaiqihuang (HQH) against cyclophosphamide (CYP)-induced hippocampal neurotoxicity based on network pharmacology, molecular docking and experimental verificati... by Yueming Zhang (790755)

“…</p>Conclusion<p>HQH mitigates CYP-induced hippocampal neurotoxicity by decreasing oxidative stress, and inflammation, with HSP90AA1 being a key target, providing a novel therapeutic strategy for chemotherapy-associated cognitive impairment.…”

Percentages of dividing lymphocytes 72 hours after mitogenic stimulation. by Fanny Gaignier (541785)

“…(<b>B</b>) Percentages of dividing CD3⁺ T cells, CD3⁺CD8⁺ Tc cells and CD3⁺CD4⁺ Th cells in response to ConA. No significant difference was obtained for dividing T cells despite the decreases observed for the HU group compared to C mice.…”

Whole-Body Counter(WBC) and food radiocesium contamination surveys in Namie, Fukushima Prefecture by Yoichiro Hosokawa (339409)

“…Moreover, the radioactivity of seven items in these 10 items decreased from fiscal 2012 to fiscal 2015. Mushrooms had high radioactivity and were produced over a wide area.…”

Dendritic Cells Regulate Treg-Th17 Axis in Obstructive Phase of Bile Duct Injury in Murine Biliary Atresia by Yong-jun Liu (5660170)

“…The proportion of Th17 cells at 7 days post-infection was decreased if Treg cells isolated from normal adult mice, but not Treg cells from the livers of mice with BA, were intraperitoneally transferred on day 5 of life. …”

Data_Sheet_1_Acupuncture With deqi Modulates the Hemodynamic Response and Functional Connectivity of the Prefrontal-Motor Cortical Network.pdf by Xiaopeng Si (11276703)

“…Results showed that: (1) acupuncture manipulation caused significantly increased acupuncture behavioral deqi performance compared with tactile controls. (2) The bilateral prefrontal cortex (PFC) and motor cortex were significantly inhibited during acupuncture manipulation than controls, which was evidenced by the decreased power of oxygenated hemoglobin (HbO) concentration. (3) The bilateral PFC’s hemodynamic responses showed a positive correlation trend with acupuncture behavioral performance. (4) The network connections with bilateral PFC as nodes showed significantly increased functional connectivity during acupuncture manipulation compared with controls. (5) Meanwhile, the network’s efficiency was improved by acupuncture manipulation, evidenced by the increased global efficiency and decreased shortest path length. …”

Table_1_Theoretical Study of Adenine to Guanine Transition Assisted by Water and Formic Acid Using Steered Molecular Dynamic Simulations.DOCX by Santiago Tolosa (6830018)

“…In the gas phase these processes indicate a slow and not spontaneous conversion (ΔG_g = 4.07 kcal·mol⁻¹, k = 5.59·10⁻⁴⁰ s⁻¹), and a lifetime for guanine of τ = 7.75·10⁺²² s. …”

Table 2_Mechanism of Huaiqihuang (HQH) against cyclophosphamide (CYP)-induced hippocampal neurotoxicity based on network pharmacology, molecular docking and experimental verificati... by Yueming Zhang (790755)

“…</p>Conclusion<p>HQH mitigates CYP-induced hippocampal neurotoxicity by decreasing oxidative stress, and inflammation, with HSP90AA1 being a key target, providing a novel therapeutic strategy for chemotherapy-associated cognitive impairment.…”

Data_Sheet_1_Burden and attributable risk factors of ischemic stroke in China from 1990 to 2019: an analysis from the Global Burden of Disease Study 2019.PDF by Yang Ye (175530)

“…</p>Results<p>From 1990 to 2019, the age-standardized deaths rate decreased by 3.3%, age-standardized DALYs rate decreased by 4%, age-standardized prevalence rate increased by 33.5%, and age-standardized incidence rate of ischemic stroke in China increased by 34.7%. …”

Data_Sheet_1_Acupuncture With deqi Modulates the Hemodynamic Response and Functional Connectivity of the Prefrontal-Motor Cortical Network.pdf by Xiaopeng Si (11276703)

“…Results showed that: (1) acupuncture manipulation caused significantly increased acupuncture behavioral deqi performance compared with tactile controls. (2) The bilateral prefrontal cortex (PFC) and motor cortex were significantly inhibited during acupuncture manipulation than controls, which was evidenced by the decreased power of oxygenated hemoglobin (HbO) concentration. (3) The bilateral PFC’s hemodynamic responses showed a positive correlation trend with acupuncture behavioral performance. (4) The network connections with bilateral PFC as nodes showed significantly increased functional connectivity during acupuncture manipulation compared with controls. (5) Meanwhile, the network’s efficiency was improved by acupuncture manipulation, evidenced by the increased global efficiency and decreased shortest path length. …”

Table 4_Mechanism of Huaiqihuang (HQH) against cyclophosphamide (CYP)-induced hippocampal neurotoxicity based on network pharmacology, molecular docking and experimental verificati... by Yueming Zhang (790755)

“…</p>Conclusion<p>HQH mitigates CYP-induced hippocampal neurotoxicity by decreasing oxidative stress, and inflammation, with HSP90AA1 being a key target, providing a novel therapeutic strategy for chemotherapy-associated cognitive impairment.…”

Effects of contralateral noise on CAEP (Lee et al., 2025) by Donguk Lee (21628297)

“…The presentation of contralateral noise had a significant effect on P1 and N1 latencies, both of which decreased. …”

RAD51 protein and mRNA in NPC cells treated with Abexinostat combined with irradiation. by Mélanie Gressette (533795)

“…In the C17-PDX treated with Abexinostat combined to irradiation the depletion of the RAD51 mRNA was modest in comparison with the protein depletion in the same tumor fragments (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0091325#pone-0091325-g005" target="_blank">Figure 5B</a>).…”

Size-frequency data and statistical distributions fitted to them. by John K. Hillier (3147690)

“…Data source and number of observed bedforms <i>n</i> are indicated on the plots; country-wide UK data (Fig 8 in [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0159489#pone.0159489.ref016" target="_blank">16</a>] and Fig 5 in [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0159489#pone.0159489.ref031" target="_blank">31</a>]) (black) and a well-studied sub-set (grey) of this [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0159489#pone.0159489.ref032" target="_blank">32</a>] are used. d) The typical shape; there are few small bedforms, a modal peak above this forming a `roll-over’, and an approximately exponential tail of frequencies decreasing towards the largest sizes.…”

Optimal Filtering Cutoff Frequency Is Determined by the Signal and Noise by Burton W Andrews (274358)

“…<div><p>(A) Insight into the relevant features of the optimal estimator can be obtained by considering a simplified model that assumes the cell measures <i>L</i> + <i>v,</i> where <i>L</i> is the true ligand concentration. …”