Optimization of the Reaction Conditions for the Synthesis of Dihydrobenzofuran Neolignans by Herbert J. Dias (4508395)

“…Under the optimized conditions, the reaction time decreased from 20 to 4 h without significantly impacting the conversion and selectivity.…”

Extracellular angiogenin levels in vivo. by Ulrika W. Nilsson Åberg (343075)

“…<p>Microdialysis in normal breast tissue and abdominal subcutaneous fat was performed in five sets of women; in follicular and luteal phases of six premenopausal women, in two consecutive luteal phases of five premenopausal women, in nine premenopausal women before and after the addition of 25 g of ground flaxseed/day to their diet, in five healthy postmenopausal women, and in 11 women before and after tamoxifen therapy as an adjuvant for early breast cancer (on two women microdialysis was performed in breast tissue only). …”

Impaired ocular growth in -mutant mice leads to microphthalmia by Lars M Ittner (15671)

Proposed model for mechanisms that contribute to gain-of-function phenotypes exhibited by truncated PFCP EPOR alleles. by Seema Singh (151638)

“…<p>For truncated EPOR alleles harbored by polycythemia patients (as diagramed) a combined set of mechanisms are proposed to lead to dysregulation of EPO/EPOR signaling (by truncated alleles, and the co-expressed wild-type EPOR). 1- Unlike the wild-type EPOR, EPOR-T alleles do not appear to accumulate within intercellular pools. 2- EPOR-T internalization is indicate to be modestly to moderately attenuated. 3- Activation of EPOR-T alleles is clearly heightened. 4- Attenuated inward trafficking also may include prolonged residence within an early lysosomal compartment. 5- As proposed previously, the truncation of C-terminal domains likely results in uncoupling from negative feed-back effects of SOCS1/3 and/or SHP1. 6- Via as yet unresolved mechanisms, expression (and ligation) of truncated EPOR alleles also results in decreased expression levels of the wild-type EPOR (as co-expressed among polycythemia patients with EPOR-T alleles).…”

Model illustration. by Elisa Omodei (782713)

“…<p>We consider a simple network of <i>N</i> = 10 users, where nodes colored in blue represent users in the <i>on</i> state, whereas red represents the <i>off</i> state. …”

Antibacterial activity of polyvinyl alcohol (PVA)/ε-polylysine packaging films and the effect on longan fruit by Yana LI (8618997)

“…<div><p>Abstract Biodegradable and antimicrobial films via combing ε-polylysine (ε-PL) and polyvinyl alcohol (PVA) is a promising material for food packaging. We prepared the ε-PL/ PVA films with the ε-PL content of 0%, 1%, 3%, 5% and 7% (wt., relative to PVA) by casting method and their physical and chemical properties were characterized. …”

Comparison of Atomic Force Microscopy and Scanning Ion Conductance Microscopy for Live Cell Imaging by Jan Seifert (517930)

Lead Sources to the Amundsen Sea, West Antarctica by Kuria Ndungu (1660531)

Acid-active cathepsins cleave phagolysosomal antigens in the MHC class II pathway. by Michael F. Criscitiello (284897)

“…Invariant chain is cleaved by cathepsins but leaves the CLIP portion (red triangle) in the MHC peptide binding site (4). In a specialized late endosome, the MHC homolog HLA-DM finally binds to the MHC class II/CLIP complex and releases CLIP (5), allowing other peptides to bind before the MHC class II travels to the cell surface (6). …”

Fig 1 - by Taehyeong Kim (8991383)

“…<p>Module-Trait Alignment <b>a.</b> Scatter plots for the addiction index and module eigen-genes of both control (addiction index = 0) and addicted mice. …”

MEI-S332 localizes to centromeres and heterochromatin. by Lin-Ing Wang (223020)

“…<p>A) MEI-S332 has enhanced recruitment to the pericentromeric regions in <i>Pp1-87B</i> RNAi oocytes and is decreased in <i>Spc105R</i> RNAi oocytes. …”

Tumor-associated MDSCs are osteoclast precursors. by Junling Zhuang (298328)

“…<p><b>A.</b> Gr-1 expression decreases with cultured time in MDSCs from myeloma-bearing mice. …”

GSNOR and ADH gene expression in lung cancer cDNA arrays. by Sarah C. Mutka (291461)

The effects of consumption inequality on SWB. by Tiantian Dong (6247917)

“…The findings indicate that consumption inequality has a significant negative impact on SWB. Specifically, for every unit increase in consumption inequality, the probability of individuals rating their SWB as “Happy” and “Very happy” decreases by 0.37% and 5.45% respectively. …”

Potential role of Saps in Cek1 phosphorylation. by Sumant Puri (300208)

“…<p><b>A.</b> Cek1 phosphorylation was determined by immunoblotting with CAI4 and with various <i>SAP</i> deletion strains, grown under germination conditions with (1 h) or without (1 h and 1.5 h) the indicated concentrations of PA. …”

Evolution of the structure and results of Primary Health Care in Brazil between 2008 and 2019 by Rafael Damasceno de Barros (13973894)

“…There was a 12% increase in median PHC spending. PHC coverage expanded, with 3,168 municipalities presenting 100% coverage in 2019, compared to 2,632 in 2008. …”

MicroRNA capture was performed with 4 different ligases using the vendor recommended protocols to compare capture efficiency across 20 different microRNA. by Yunke Song (550035)

“…Capture efficiency was determined by performing a Cy3 scan and comparing the intensities of the ∼40 nt captured microRNA band versus the ∼20 nt free microRNA band. …”

BCFMT depolymerized microtubules of MCF-7 cells. by Ankit Rai (139736)

“…<p>(A) Cells were treated without and with 40 µM BCFMT for 3 h and microtubules were stained using antibody against α-tubulin (red). …”

File S1 - Characterisation of AmphiAmR11, an Amphioxus (<i>Branchiostoma floridae</i>) D₂-Dopamine-Like G Protein-Coupled Receptor by Asha L. Bayliss (483520)

“…Effect of biogenic amines (A) and synthetic agonists (B) on forskolin-stimulated cAMP levels in AmphiAmR11-expressing CHO-K1 cells. …”

Gray matter alterations in the hippocampus and diffusion anisotropy with HYDI. by Madelaine Daianu (831026)

“…Diffusion anisotropy in the hippocampus with decreases in the apparent FA (<i>P</i> = 6.6x10^-5) and increases in GFA (<i>P</i> = 1.8x10^-4) with increasing number of <i>q</i>-sampling shells. …”