Shear Stress-Induced Alteration of Epithelial Organization in Human Renal Tubular Cells by Damien Maggiorani (765804)

“…Results were confirmed <i>in vivo</i> in a uninephrectomy (8 months) mouse model where increased FSS induced by adaptive hyperfiltration in remnant kidney was accompanied by both decreased epithelial gene expression including ZO-1, E-cadherin and β-Catenin and disappearance of tubular cilia. …”

Data_Sheet_3_Exploring the potential mechanism of Xiaojin Pill therapy for benign prostatic hyperplasia through metabolomics and gut microbiota analysis.zip by Yuying Yang (4111534)

“…L-arginine plays a pivotal role in metabolic pathways encompassing pyrimidine metabolism, arginine biosynthesis, and the mammalian target of rapamycin (mTOR) signaling pathway. 16S rRNA sequencing revealed that XJP optimized the diversity and balance of intestinal flora in BPH rats by decreasing the Bacteroidetes/Firmicutes (B/F) ratio, enhancing the beneficial bacteria, such as Eggerthellaceae, Anaerovoracaceae, and Romboutsia, and suppressing the dysfunctional bacteria, such as Atopobiaceae, Prevotellaceae_NK3B31_group, Dorea, and Frisingicoccus. …”

Application of Multiplexed Ion Mobility MS for Identification of Protein Signatures of Treatment of Tuberculosis (Cascadia proteomics symposium 2017) by PNNL Omics (4106851)

“…Additional examples of proteins increased after 8 weeks of treatment are endothelial protein C receptor (EPCR), serine protease inhibitor (IPSP), and plasminogen (PLMN). Notable proteins decreasing with treatment were fibrinogen alpha chain (FIBA), factor IX (FA9), factor V (FA5), and platelet glycoprotein V (GPV). …”

Data_Sheet_2_Exploring the potential mechanism of Xiaojin Pill therapy for benign prostatic hyperplasia through metabolomics and gut microbiota analysis.docx by Yuying Yang (4111534)

“…L-arginine plays a pivotal role in metabolic pathways encompassing pyrimidine metabolism, arginine biosynthesis, and the mammalian target of rapamycin (mTOR) signaling pathway. 16S rRNA sequencing revealed that XJP optimized the diversity and balance of intestinal flora in BPH rats by decreasing the Bacteroidetes/Firmicutes (B/F) ratio, enhancing the beneficial bacteria, such as Eggerthellaceae, Anaerovoracaceae, and Romboutsia, and suppressing the dysfunctional bacteria, such as Atopobiaceae, Prevotellaceae_NK3B31_group, Dorea, and Frisingicoccus. …”

Densitometric quantitation of differential protein expression in controls, type 1 diabetic patients with end-stage renal disease (T1D+ESRD), and kidney-pancreas transplanted patien... by Franco Folli (195509)

“…Catalase expression decreased 25-fold (p<0.001) (<u>A</u>) and phosphoglycerate kinase 1 expression decreased 4-fold (p<0.01) (A) in T1D+ESRD group compared with controls. …”

Data_Sheet_4_Exploring the potential mechanism of Xiaojin Pill therapy for benign prostatic hyperplasia through metabolomics and gut microbiota analysis.docx by Yuying Yang (4111534)

“…L-arginine plays a pivotal role in metabolic pathways encompassing pyrimidine metabolism, arginine biosynthesis, and the mammalian target of rapamycin (mTOR) signaling pathway. 16S rRNA sequencing revealed that XJP optimized the diversity and balance of intestinal flora in BPH rats by decreasing the Bacteroidetes/Firmicutes (B/F) ratio, enhancing the beneficial bacteria, such as Eggerthellaceae, Anaerovoracaceae, and Romboutsia, and suppressing the dysfunctional bacteria, such as Atopobiaceae, Prevotellaceae_NK3B31_group, Dorea, and Frisingicoccus. …”

DataSheet1_Suppression of PTRF Alleviates Post-Infectious Irritable Bowel Syndrome via Downregulation of the TLR4 Pathway in Rats.ZIP by Hui-hui Zhou (11532046)

“…<p>Background: Accumulating evidence suggests that the polymerase I and transcript release factor (PTRF), a key component of the caveolae structure on the plasma membrane, plays a pivotal role in suppressing the progression of colorectal cancers. …”

Data_Sheet_1_Exploring the potential mechanism of Xiaojin Pill therapy for benign prostatic hyperplasia through metabolomics and gut microbiota analysis.xls by Yuying Yang (4111534)

“…L-arginine plays a pivotal role in metabolic pathways encompassing pyrimidine metabolism, arginine biosynthesis, and the mammalian target of rapamycin (mTOR) signaling pathway. 16S rRNA sequencing revealed that XJP optimized the diversity and balance of intestinal flora in BPH rats by decreasing the Bacteroidetes/Firmicutes (B/F) ratio, enhancing the beneficial bacteria, such as Eggerthellaceae, Anaerovoracaceae, and Romboutsia, and suppressing the dysfunctional bacteria, such as Atopobiaceae, Prevotellaceae_NK3B31_group, Dorea, and Frisingicoccus. …”

DataSheet3_Suppression of PTRF Alleviates Post-Infectious Irritable Bowel Syndrome via Downregulation of the TLR4 Pathway in Rats.ZIP by Hui-hui Zhou (11532046)

“…<p>Background: Accumulating evidence suggests that the polymerase I and transcript release factor (PTRF), a key component of the caveolae structure on the plasma membrane, plays a pivotal role in suppressing the progression of colorectal cancers. …”

DataSheet2_Suppression of PTRF Alleviates Post-Infectious Irritable Bowel Syndrome via Downregulation of the TLR4 Pathway in Rats.ZIP by Hui-hui Zhou (11532046)

“…<p>Background: Accumulating evidence suggests that the polymerase I and transcript release factor (PTRF), a key component of the caveolae structure on the plasma membrane, plays a pivotal role in suppressing the progression of colorectal cancers. …”

Optimizing replay intensity and resolution in aberration-compensated off-axis holograms by ambient humidity control by Henry Nebrensky (1229277)

“…Roderic Lakes extracted using <a href="http://www.unige.ch/sciences/chifi/cpb/windig.html">WinDIG</a> version 2.5.…”

Contribution of GCYs and PDEs on cGMP and Ca²⁺ dynamics in AFD cultivated at different temperature. by Ichiro Aoki (244203)

“…Ca²⁺ level in soma is actively decreased via the three GCYs (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0278343#pone.0278343.s003" target="_blank">S3 Fig</a>) and SLO-2 potassium channel [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0278343#pone.0278343.ref040" target="_blank">40</a>]. …”

<i>H</i>. <i>pylori</i> TlpD-dependent chemoattraction to sources of HOCl. by Arden Perkins (1346853)

“…(C) Experiments performed as in panel A with HOCl for the <i>tlpD</i> G27 (gray, 3-second time traces) and <i>tlpABC</i> G27 (pink, 5-second time traces) mutants. …”

Dynamics of actin filaments within single dendritic spine with TEA treatment. by Jian-Hua Chen (373793)

“…<i>vs</i>. 1588 a.u. ± 331.5 a.u.; p = 0.0243). FCS measurements were done directly before TEA treatment and 30 minutes thereafter. …”

Germline Mutations in <i>Mtap</i> Cooperate with <i>Myc</i> to Accelerate Tumorigenesis in Mice by Yuwaraj Kadariya (426943)

“…Surprisingly, examination of <i>Mtap</i> status in lymphomas in <i>Eµ-myc Mtap^lacZ/+</i> and <i>Eµ-myc Mtap^+/+</i> animals did not reveal significant differences in the frequency of loss of Mtap protein expression, despite having shorter latency times, suggesting that haploinsufficiency of <i>Mtap</i> may be playing a direct role in accelerating tumorigenesis. Consistent with this idea, microarray analysis on liver tissue from age and sex matched <i>Mtap^+/+</i> and <i>Mtap^lacZ/+</i> animals found 363 transcripts whose expression changed at least 1.5-fold (P<0.01). …”

Image_3_CLEC4s as Potential Therapeutic Targets in Hepatocellular Carcinoma Microenvironment.TIF by Yinjiang Zhang (5030006)

“…Furthermore, the expression of CLEC4H1 (ASGR1) and CLEC4H2 (ASGR2) exhibited a significant relation to clinical stages. However, the expression of CLEC4A, CLEC4D, CLEC4E, CLEC4J (FCER2), CLEC4K (CD207), CLEC4G, CLEC4H1, CLEC4M, and CLEC4H2 decreased with tumor progression. …”

Synthetic Approach To Determine the Effect of Nuclear Spin Distance on Electronic Spin Decoherence by Michael J. Graham (1799677)

“…Our studies demonstrate a sharp jump in <i>T</i>₂ when the average V–H distance is decreased from 6.6(6) to 4.0(4) Å, indicating that spin-active nuclei sufficiently close to the electronic spin center do not contribute to decoherence. …”

Table_1_Impact of Computed Tomography-Based, Artificial Intelligence-Driven Volumetric Sarcopenia on Survival Outcomes in Early Cervical Cancer.docx by Qingling Han (11477659)

“…During primary treatment, significant decreases in waist skeletal muscle (median, −3.9%; p < 0.001) and total fat (median, −5.3%; p < 0.001) were observed. …”

Table_1_Acromegaly: The Research and Practical Value of Noninvasive Hemodynamic Assessments via Impedance Cardiography.docx by Agnieszka Jurek (9019094)

“…</p>Conclusions<p>Even with well-controlled hypertension, AC is associated with a high TFC, increased heart rate, and decreased indices of cardiac contractility. …”

DataSheet_1_Proinflammatory mucosal-associated invariant CD8+ T cells react to gut flora yeasts and infiltrate multiple sclerosis brain.pdf by Francesca Gargano (11333907)

“…We then found that in pwMS, a distinct population of cells with antibacterial and antifungal activity is expanded during the remitting phase and markedly decreases during clinically and/or radiologically active disease. …”