Distribution of fitness effects of new mutations. by Boaz Shvartzman (18272357)

“…<p><b>(A)</b> The distribution of fitness effects (DFE) evolved during the <i>in-silico</i> evolutionary experiment: the frequency of lethal mutations decreased (red line) and the frequency of neutral and slightly deleterious mutations increased (blue line). …”

Magnetic tweezers setup for parallel translation of bead chains. by Kaiyuan Yang (135297)

“…Scale bar, 5 mm. (c): A 21-bead chain in the magnetic field of a single cone magnet, aligning with the field <b>B</b> (white arrow) along the <i>x</i>-axis, and translating towards the magnetic field gradient ∇<b>B</b> (black arrow). …”

The application of Compont gel in chronic obstructive jaundice rats model by Wei-wei Luo (6798557)

“…Results: Group B showed a fluctuant development of jaundice, obstructive degree reached a peak at 2 weeks, and decreased from 3 weeks. …”

Supplementation of copaiba or sucupira oils in broiler diets by Raiana Almeida Noleto (4643071)

“…Data were submitted to analysis of variance and Tukey test (5%). The addition of sucupira oil at 500 mg/kg decreased broiler performance at 21, 33, and 40 days of age, whereas the addition of copaiba oil resulted in similar performance relative to the antibiotic. …”

PHGDH upregulation by the HER2 oncogene supports insulin-independent proliferation of MCF10HER2 cells. by Aliccia Bollig-Fischer (227291)

“…The experiment was done using two PHGDH-targeted vectors and a non-silencing control vector. While mRNA levels were reduced nearly 80%, the amount of protein appears to be decreased by only one half. …”

Alternate display format of TAG/DAG-species and FA-species. by Thomas Kopf (548745)

“…In the diagrams the species shown in red have increased levels between the two respective groups, while a blue color indicates a decreased level of the respective species between the two groups. …”

Kinetic parameter differences between leukemic and healthy cells. by Daphne Ezer (3072147)

“…<p>This figure illustrates kinetic parameter change predictions for the single cell qPCR data in Guo et al. Just as in Figs <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1005072#pcbi.1005072.g005" target="_blank">5</a> and <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1005072#pcbi.1005072.g006" target="_blank">6</a>, red boxes indicate that <i>K</i>_<i>on</i> varies, yellow boxes indicate that <i>K</i>_<i>t</i> varies and orange boxes signify that both parameters change. …”

Zinc Complex-Based Multifunctional Reactive Lithium Polysulfide Trapper Approaching Its Theoretical Efficiency by Zhong Ma (379315)

“…LSBs using Zn­(OAc)₂·DEA as the LPS trapper, binder, and redox catalyst exhibited excellent long-term cycling stability (with a capacity retention of 85% after 1000 cycles at a rate of 0.5C) and enhanced rate performance. …”

<i>Gemini</i> encodes both functional enzymatic and fluorescence activities. by Lance Martin (257830)

“…Specifically, we placed all three reporters under the control of a medium strength RBS (BBa_B0032) and four different promoters of variable strength (in order of decreasing strength BBa_J23119, 101, 106, 115) on a low-copy vector (BBa_PSB4A5). …”

Zinc Complex-Based Multifunctional Reactive Lithium Polysulfide Trapper Approaching Its Theoretical Efficiency by Zhong Ma (379315)

“…LSBs using Zn­(OAc)₂·DEA as the LPS trapper, binder, and redox catalyst exhibited excellent long-term cycling stability (with a capacity retention of 85% after 1000 cycles at a rate of 0.5C) and enhanced rate performance. …”

Aneuploidy formation and FLC resistance in the <i>C. neoformans</i> strain H99. by Kyung J. Kwon-Chung (51675)

“…<p>(A) The percentage of FLC-resistant population in H99^R64 (resistant at 64 ug/ml FLC) decreases during daily transfer in drug-free media. …”

Magnetic tweezers setup for perpendicular translation of bead chains. by Kaiyuan Yang (135297)

“…Scale bar, 5 mm. (c): As viewed in the field of view, a 24-bead chain in the magnetic field of a pair of magnets, aligning with the field <b>B</b> (white arrow) along the <i>y</i>-axis, and translating towards the magnetic field gradient ∇<b>B</b> (black arrow). …”

Reconstruction model for the <i>Candida</i> genetic code alteration. by Isabel Miranda (8055)

“…<p>The ancestor of <i>Candida</i> decoded the CUG codon as leucine using a single leucine tRNA (tRNA^Leu). This situation changed dramatically with appearance 272±25My of a mutant serine tRNA that acquired a 5′-CAG-3′anticodon (tRNA_CAG^Ser). …”

The α₁-adrenoceptors in the mouse femoral arterial bed are of the α_1L-subtype. by Joseph Zacharia (420909)

“…</i> Prazosin (10.0 nM to 1.0 µM) produced successive increases in fractional diameter (i.e. decreased active vascular tone). These arteries were isolated and mounted on a wire myograph for force measurement (B) <i>Ex vivo</i> characterization of α₁-receptors in femoral artery: Prazosin (10 nM–1 µM, n = 5) produced concentration-dependent parallel rightward shifts in the potency of phenylephrine (PE) without significantly affecting the maximum responses. …”

Zinc Complex-Based Multifunctional Reactive Lithium Polysulfide Trapper Approaching Its Theoretical Efficiency by Zhong Ma (379315)

“…LSBs using Zn­(OAc)₂·DEA as the LPS trapper, binder, and redox catalyst exhibited excellent long-term cycling stability (with a capacity retention of 85% after 1000 cycles at a rate of 0.5C) and enhanced rate performance. …”

Citral inhibition of I_TRPV1 reveals the expression of TRPV2 and TRPV3 in acutely isolated dorsal root ganglion neurons. by Stephanie C. Stotz (129157)

“…<p>(A) Two patterns of response to repetitive 2-aminoethyldiphenyl borate application were noted within the dorsal root ganglion population following citral block of capsaicin-activated currents; dorsal root ganglion currents decreased in six neurons (left), and increased in the remaining neurons (right; n = 6; +100 mV). …”

Sensitivity of the mitotic checkpoint response. by Fridolin Gross (384234)

“…It is reasonable to assume that the association rate for an active checkpoint lies between 5 and 500 (in units of 1/min*[total Mad]) [<a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1006449#pcbi.1006449.ref014" target="_blank">14</a>, <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1006449#pcbi.1006449.ref042" target="_blank">42</a>]. …”

Real-world image processing. by Alejandro Lerer (10702204)

“…<p>(A) Top: Fruits image with additive white noise (SNR = 2.6266dB and PSNR = 8.9813dB) along with the corresponding model output (SNR = 5.4682db and PSNR = 11.8228dB); The models capacity for noise removal is worse than an algorithm based on Tikhonov regularization (SNR = 8.30dB and PSNR = 14.65dB; [<a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1007907#pcbi.1007907.ref111" target="_blank">111</a>]. …”

Analysis of Chimpanzee History Based on Genome Sequence Alignments by Jennifer L. Caswell (89812)

“…We infer that the central chimpanzee population size increased by at least a factor of 4 since its separation from western chimpanzees, while the western chimpanzee effective population size decreased. …”

Horizontal axons exhibit pause behavior in response to high-frequency photostimulation directed at the soma of labeled neurons. by Olga Malyshevskaya (501664)

“…After the photostimulation at 475-nm excitation, the axon was further observed at 560-nm excitation. Scale bar, 5 µm. <b>B,</b> Growth of the horizontal axon shown in A. …”