Antagonistic Regulation of Parvalbumin Expression and Mitochondrial Calcium Handling Capacity in Renal Epithelial Cells by Thomas Henzi (822552)

“…Using Gene Chip Arrays and qRT-PCR, we identified differentially expressed genes in the DCT of PV-/- mice. With a focus on genes implicated in mitochondrial Ca²⁺ transport and membrane potential, uncoupling protein 2 (<i>Ucp2</i>), mitocalcin (<i>Efhd1</i>), mitochondrial calcium uptake 1 (<i>Micu1</i>), mitochondrial calcium uniporter (<i>Mcu</i>), mitochondrial calcium uniporter regulator 1 (<i>Mcur1</i>), cytochrome c oxidase subunit 1 (<i>COX1</i>), and ATP synthase subunit β (<i>Atp5b</i>) were found to be up-upregulated. …”

Population Structure, Genetic Diversity, Effective Population Size, Demographic History and Regional Connectivity Patterns of the Endangered Dusky Grouper, <i>Epinephelus marginatu... by Molly Buchholz-Sørensen (3147255)

“…A contemporary modest mean size was observed, 3 ± 3 kg, where approximately 17% of the population was juvenile, 68% female/sex-changing and 15% were male with a male-to-female sex ratio of 1:5. …”

Flexible Microfluidic Devices for Tunable Formation of Double Emulsion by Uditha Roshan (20841937)

Although Hrq1 is needed for cisplatin resistance, it is degraded by the proteasome upon cisplatin exposure. by Thong T. Luong (13833935)

“…The experiment was performed five times with mean and standard error plotted (Raw densitometry data in Sheets A-E in <b><a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1010122#pgen.1010122.s007" target="_blank">S1 Data</a></b>). …”

Image_4_Initial WNT/β-Catenin Activation Enhanced Mesoderm Commitment, Extracellular Matrix Expression, Cell Aggregation and Cartilage Tissue Yield From Induced Pluripotent Stem Ce... by Ursula Kreuser (9581357)

“…Importantly, the initial CHIR pulse increased cell proliferation until day 14 (five-fold), adjusted expression of adhesion-related genes (CDH3 up, CDH6 down) and increased extracellular matrix (ECM)-related gene expression (COL6, COL1, COL3, COL5, DCN, NPNT, LUM, MGP, MATN2, and VTN), thus yielding more matrix-interacting progenitors with a high aggregation capability. …”

Flexible Microfluidic Devices for Tunable Formation of Double Emulsion by Uditha Roshan (20841937)

Flexible Microfluidic Devices for Tunable Formation of Double Emulsion by Uditha Roshan (20841937)

Table 1_Integrated analysis of single-cell and bulk transcriptomics reveals the prognostic value and underlying mechanisms of crotonylation in ovarian cancer.xlsx by Xiaofeng Li (342614)

“…Background<p>Ovarian cancer remains the deadliest gynecological malignancy with 5-year survival rates below 40% due to frequent recurrence and chemoresistance. …”

image_1_Impaired Differentiation of Langerhans Cells in the Murine Oral Epithelium Adjacent to Titanium Dental Implants.jpeg by Oded Heyman (5139533)

“…Further analysis revealed that while the expression of the TGF-β1 canonical receptor activing-like kinase (ALK)5 was upregulated, expression of its non-canonical receptor ALK3 was decreased. …”

Data_Sheet_1_Impact of Sleep–Wake-Associated Neuromodulators and Repetitive Low-Frequency Stimulation on Human iPSC-Derived Neurons.docx by Remi Yokoi (6750716)

“…The number of SBFs repeatedly increased up to 5 h after 100 nM serotonin administration, inducing a 24-h rhythm cycle. …”

MiR144/451 expression is epigenetically repressed during megakaryocytic differentiation. by Nicole Kohrs (3175914)

“…<p><b>(A)</b> MiR144/451 expression is decreased upon megakaryocytic differentiation and increased upon erythroid expression of primary hCD34+ cells. …”

Image_3_Cyclic Stretch Induces Vascular Smooth Muscle Cells to Secrete Connective Tissue Growth Factor and Promote Endothelial Progenitor Cell Differentiation and Angiogenesis.TIF by Jing Yan (312090)

“…In vitro, EPCs were cocultured with VSMCs, which were exposed to cyclic stretch at a magnitude of 5% (which mimics physiological stretch) and a constant frequency of 1.25 Hz for 12 h. …”

Flexible Microfluidic Devices for Tunable Formation of Double Emulsion by Uditha Roshan (20841937)

Ghrelin Gene Variants Influence on Metabolic Syndrome Components in Aged Spanish Population by Mireia Mora (512120)

“…A/A genotype of -501AC polymorphism was associated to decreased BMI. …”

GA-Responsive Dwarfing Gene <i>Rht12</i> Affects the Developmental and Agronomic Traits in Common Bread Wheat by Liang Chen (73736)

“…However, <i>Rht12</i> delayed anthesis date by around 5 days and even the dominant <i>Vrn-B1</i> allele could not compensate this negative effect. …”

Late Permian–Triassic siliciclastic provenance, palaeogeography, and crustal growth of the Songpan terrane, eastern Tibetan Plateau: evidence from U–Pb ages, trace elements, and Hf... by Yu-Xiu Zhang (686536)

“…The detrital zircons from Middle–Late Triassic siliciclastic rocks exhibit wide age spectra with two dominant populations of 230–600 Ma and >1600 Ma, peaking at ~1.8–1.9 Ga and ~2.4–2.5 Ga, suggestive of a derivation from the Qinling, Qilian, and Kunlun orogens and the Yangtze Craton being the minor source area. …”

Stimulus-driven Blondel communities proofed that both affected subnetworks were an interconnected system. by Isabel Wank (12475626)

“…Different functional groups are distinguished by the node colors (see legend in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0266669#pone.0266669.g005" target="_blank">Fig 5</a>), the size of the node represents the node degree (number of connections one functional group has to each other and also within the group). …”

Restraint stress induces uterine microenvironment disorder in mice during early pregnancy through the β₂-AR/cAMP/PKA pathway by Jiayin Lu (716730)

“…PCR analysis demonstrated that β₂-AR expression levels in embryo day (E) 3, 5 and 7 were kept at a significantly higher level (<i>p</i> < 0.05) under restraint stress and higher than β₁-AR and β₃-AR in different gestation ages. …”

Image_1_Insights Into Pulp Biomineralization in Human Teeth.TIF by Rui He (824726)

“…The biomolecules osteopontin (OPN), osteocalcin (OCN), osterix (OSX), and bone sialoprotein (BSP) were immunolocalized around PGP 9.5 positive neurovascular bundles in MP. SEM and STEM revealed a wide range of nano/micro particulates in dentin tubules and spherulitic mineral aggregates in the collagen with intrafibrillar mineral surrounding neurovascular bundles. …”

Dopants Control Electron–Hole Recombination at Perovskite–TiO₂ Interfaces: <i>Ab Initio</i> Time-Domain Study by Run Long (1304349)