Mechanism of fast calcium release triggered by RyRs. by Kanishka Basnayake (6796661)

“…Initially, <i>n</i>_<i>Ca</i> = 8 and decreases exponentially with a time constant of 360 ms. …”

Profile-QSAR and Surrogate AutoShim Protein-Family Modeling of Proteases by Prasenjit Mukherjee (2041477)

“…Analysis suggested that the higher structural diversity of the protease structures, as well as smaller assay data sets and fewer potent compounds, both contributed to the decreased predictive power. In a prospective virtual screening application, 32 compounds were ordered from a 1.5 million archive and tested in a biochemical assay. …”

Flow cytometry results showing reduced numbers of GFP-positive NALM6 cells and increased cell death after pEGFP-TES transfection. by Robert J. Weeks (3176793)

“…<p>Transfected NALM6 cells (24 hours post-transfection) were labelled with Annexin V and VLD and analysed by flow cytometry. (A) Decreased numbers of GFP-positive NALM6 cells were present after pEGFP-TES transfection (p<0.001). …”

RNA sequencing of key brain regions in <i>Trappc9</i> deficient mice. by Zhengzheng S. Liang (9333660)

“…<p>(A) <i>Trappc9</i> transcripts abundance showed 18%, 53% and 74% reduction compared to the wild-type expression level in hippocampus, (B) and decreased by 23%, 63% and 79% of the wild-type expression level in hypothalamus (average expression across 5 females per genotype). …”

Bifurcation figures of the S-I-P-B dynamics, presenting maximum and minimum values (black circles), as well as equilibrium densities when competitor (<i>B</i>) is not present (red... by Ilona Merikanto (115920)

“…<p>In all the figures <i>f_PB</i> = 10⁻⁷. a) When outside-host growth rate of pathogen (<i>r_P</i>) is 0.05 and the competition coefficient (<i>f_BP</i>) is 10⁻⁵, decreasing <i>r_S</i> destabilizes the disease dynamics. b) When <i>r_P</i> is (0.05) and <i>f_BP</i> is higher (10⁻⁴), pathogen population is able to increase and the dynamics are locally stable and all four populations coexist.…”

Image_1_Weaning Age Affects the Development of the Ruminal Bacterial and Archaeal Community in Hu Lambs During Early Life.JPEG by Huiling Mao (6520772)

“…Compared to W30, PW30 had a decreased relative abundance of Bacteroidetes. …”

Table_1_Weaning Age Affects the Development of the Ruminal Bacterial and Archaeal Community in Hu Lambs During Early Life.DOCX by Huiling Mao (6520772)

“…Compared to W30, PW30 had a decreased relative abundance of Bacteroidetes. …”

DataSheet1_Dynamic changes in soil moisture in three typical landscapes of the Heihe River Basin.docx by Qianqian Gou (9693824)

“…The soil moisture content in the mid-reach initially increased, later decreased, and ultimately attained its highest level at 40–60 cm; however, the soil moisture content in the lower reach increased, and reached its highest level at 120–160 cm. 3) In the upper and middle reaches, the coefficient of variation of soil moisture decreased with an increasing soil depth, whereas the lower reach exhibited a converse trend. …”

GATA elements control repression of cardiac troponin I promoter activity in skeletal muscle cells-7 by Raffaella Di Lisi (63653)

“…Each construct was tested in 4 to 5 independent experiments.…”

GATA elements control repression of cardiac troponin I promoter activity in skeletal muscle cells-1 by Raffaella Di Lisi (63653)

“…Each construct was tested in 4 to 5 independent experiments.…”

TNNI3K expression leads to premature death in the <i>Csq</i> transgenic model of cardiomyopathy. by Ferrin C. Wheeler (259443)

“…Survival is severely decreased for double positive transgenics (<i>TNNI3K^tg</i>/<i>Csq^tg</i>) to an average of 17 days with a range from 15 to 21 days. …”

table1_Ganghuo Kanggan Decoction in Influenza: Integrating Network Pharmacology and In Vivo Pharmacological Evaluation.xlsx by Yanni Lai (7865978)

“…After the treatment with GHKGD, the level of Th1 cytokines (IFN-γ, TNF-α, IL-2) was increased, while the expression of Th2 (IL-5, IL4) cytokines was reduced (p < 0.05).</p><p>Conclusion: Through a network pharmacology strategy and in vivo experiments, the multi-target and multi-component pharmacological characteristics of GHKGD in the treatment of influenza were revealed, and regulation of the RLR signaling pathway during the anti-influenza process was confirmed. …”

table3_Ganghuo Kanggan Decoction in Influenza: Integrating Network Pharmacology and In Vivo Pharmacological Evaluation.xlsx by Yanni Lai (7865978)

“…After the treatment with GHKGD, the level of Th1 cytokines (IFN-γ, TNF-α, IL-2) was increased, while the expression of Th2 (IL-5, IL4) cytokines was reduced (p < 0.05).</p><p>Conclusion: Through a network pharmacology strategy and in vivo experiments, the multi-target and multi-component pharmacological characteristics of GHKGD in the treatment of influenza were revealed, and regulation of the RLR signaling pathway during the anti-influenza process was confirmed. …”

table2_Ganghuo Kanggan Decoction in Influenza: Integrating Network Pharmacology and In Vivo Pharmacological Evaluation.xlsx by Yanni Lai (7865978)

“…After the treatment with GHKGD, the level of Th1 cytokines (IFN-γ, TNF-α, IL-2) was increased, while the expression of Th2 (IL-5, IL4) cytokines was reduced (p < 0.05).</p><p>Conclusion: Through a network pharmacology strategy and in vivo experiments, the multi-target and multi-component pharmacological characteristics of GHKGD in the treatment of influenza were revealed, and regulation of the RLR signaling pathway during the anti-influenza process was confirmed. …”

Data_Sheet_1_Influence of Previous General Anesthesia on Cognitive Impairment: An Observational Study Among 151 Patients.PDF by Federico Linassi (9909875)

“…</p>Results<p>We discovered a general cognitive function impairment of 79.5% and an executive function impairment of 22%. …”

Supplementary information files for Mechanics of ballistic impact with non-axisymmetric projectiles on thin aluminium targets. Part I: Failure mechanisms by Theodosios Stergiou (10325309)

“…Overall, the critical velocity showed a quadratic dependence on deq/hT , where the benefit of ballistic performance decreased with an increase in this ratio. …”

Data_Sheet_1_Case Report: Event-Related Desynchronization Observed During Volitional Swallow by Electroencephalography Recordings in ALS Patients With Dysphagia.pdf by Akari Ogawa (12093176)

“…It is caused by degeneration of both the bulbar motor neurons and cortical motoneurons projecting to the oropharyngeal areas. A previous report showed decreased event-related desynchronization (ERD) in the medial sensorimotor areas in ALS dysphagic patients. …”

AsrR Is an Oxidative Stress Sensing Regulator Modulating <em>Enterococcus faecium</em> Opportunistic Traits, Antimicrobial Resistance, and Pathogenicity by François Lebreton (146507)

“…Consistent with the upregulated expression of the <em>pbp5</em> gene, encoding a low-affinity penicillin-binding protein, the <em>asrR</em> null mutant was found to be more resistant to β-lactam antibiotics. …”

Data_Sheet_1_Integrated Analysis of the Alterations in Gut Microbiota and Metabolites of Mice Induced After Long-Term Intervention With Different Antibiotics.zip by Nan Zhang (46264)

“…Serum cytokines (IFN-γ, IL-2, IL-10, IL-13, IL-17A, and TNF-α) were determined by multiplex immunoassay.…”

<i>tbc-8(tm3802)</i> mutant shows defects in DCV maturation. by Mandy Hannemann (162954)

“…Strikingly, the catalytically inactive TBC-8 (R697A) mutant was not able to rescue the DCV phenotype, emphasizing that its GAP activity is responsible for decreased NLP-21-derived VENUS levels at the axons and in coelomocytes. …”