Image_2_Effect of 15 days −6° head-down bed rest on microbial communities of supragingival plaque in young men.TIF by Di Zhu (1450108)

“…</p>Methods<p>Sixteen healthy male volunteers were recruited, and supragingival plaque samples were collected under −6° head-down bed rest (HDBR) at five-time points: day 1 before HDBR; days 5, 10, and 15 of HDBR; and day 6 of recovery. …”

Administration of the NFκB inhibitor PDTC abrogates UVB-induced skin carcinogenesis in SKH-1 mice. by Hyunmi Kim (156020)

“…<p>SKH-1 mice (n = 30 per treatment) were chronically irradiated with UVB (180 mJ/cm², twice a week for 35 weeks) and either given PDTC (0.5%) or no treatment in drinking water (<i>ad libitum</i>). …”

Image_1_Quercetin activates vitamin D receptor and ameliorates breast cancer induced hepatic inflammation and fibrosis.TIF by Nirmala G. Sannappa Gowda (14666519)

“…Liver enzymes activity was determined using a spectrophotometric assay. The hallmarks of inflammation and fibrosis were determined using Immunohistochemistry. …”

Data_Sheet_1_Global Burden Attributable to High Low-Density Lipoprotein-Cholesterol From 1990 to 2019.docx by Heyue Du (11229207)

“…Background<p>High low-density lipoprotein-cholesterol (LDL-C) is a public health issue contributing to ischemic heart disease (IHD) and stroke.…”

Image_3_Effect of 15 days −6° head-down bed rest on microbial communities of supragingival plaque in young men.TIF by Di Zhu (1450108)

“…</p>Methods<p>Sixteen healthy male volunteers were recruited, and supragingival plaque samples were collected under −6° head-down bed rest (HDBR) at five-time points: day 1 before HDBR; days 5, 10, and 15 of HDBR; and day 6 of recovery. …”

Image6_Elabela Attenuates the TGF-β1-Induced Epithelial-Mesenchymal Transition of Peritoneal Mesothelial Cells in Patients Receiving Peritoneal Dialysis.tif by Shunyun Xie (12898211)

“…Compared with those in patients with stage 5 chronic kidney disease who are not on dialysis, serum ELA levels in patients on PD increased with the improvement of residual renal function at PD duration <36 months and decreased to pre-dialysis levels at PD duration ≥36 months, suggesting that dialysis duration is the main risk factor affecting serum ELA levels in patients on PD. …”

Table 1_Constraint-based modeling of bioenergetic differences between synaptic and non-synaptic components of dopaminergic neurons in Parkinson’s disease.docx by Xi Luo (361139)

“…The synaptic PD model predicted a lower mitochondrial energy contribution and higher sensitivity to Complex I inhibition compared to the non-synaptic PD model. …”

Appendix 4 Included Studies BEME Virtual Interviews in Graduate Medical Education by Jennifer Westrick (13161909)

“…The optimal future state remains unclear, though a hybrid model (e.g., VIs followed by a limited number of in-person second looks) may optimize strengths and weaknesses.…”

Image2_Elabela Attenuates the TGF-β1-Induced Epithelial-Mesenchymal Transition of Peritoneal Mesothelial Cells in Patients Receiving Peritoneal Dialysis.TIF by Shunyun Xie (12898211)

“…Compared with those in patients with stage 5 chronic kidney disease who are not on dialysis, serum ELA levels in patients on PD increased with the improvement of residual renal function at PD duration <36 months and decreased to pre-dialysis levels at PD duration ≥36 months, suggesting that dialysis duration is the main risk factor affecting serum ELA levels in patients on PD. …”

Leukocyte Populations in Human Preterm and Term Breast Milk Identified by Multicolour Flow Cytometry by Stephanie Trend (688419)

“…</p><p>Conclusions</p><p>Flow cytometry is a useful tool to identify and quantify leukocyte subsets in breast milk. …”

Cortical and subcortical regions feature distinct early and late responses during audition. by Sarah H. McGill (22505225)

“…Warmer tones indicate increases in spectral power within maximum-intensity stimulus trials over no-stimulus trials, while cooler tones indicate decreases. <b>(A)</b> Frontal association cortex, (B) centrolateral thalamic nucleus, and (C) primary auditory cortex show early increases in alpha (8-12 Hz), beta (12-30 Hz), and gamma (30-100 Hz) band frequencies with late decreases in alpha and beta frequency bands. …”

Quantitative T₂ and T₂* mapping at 10 weeks post infection. by Brice Masi (798438)

“…(<b>E)</b> Distributions of hepatic T₂* values at 10 weeks post infection showing decreased T₂* values (P < 0.01) in the infected mice (n = 4) compared to controls (n = 5).…”

Data_Sheet_1_The response of nutrient cycle, microbial community abundance and metabolic function to nitrogen fertilizer in rhizosphere soil of Phellodendron chinense Schneid seedl... by Yuanzheng Gu (244592)

“…N10 treatment significantly increased the contents of available phosphorus (AP), available potassium (AK), ammonium nitrogen (NH₄⁺-N), nitrate nitrogen (NO₃⁻-N) and sucrase (SU) activity, as well as fungal diversity and the relative expression abundances of amoA and phoD genes in rhizosphere soil, but observably decreased the total phosphorus (TP) content, urease (UR) activity and bacterial diversity, among which the pH, soil organic matter (SOM), AP, NH₄⁺-N and NO₃⁻-N were the main environmental factors for affecting rhizosphere soil microbial community structure based on RDA and correlation analyses. …”

Image9_Elabela Attenuates the TGF-β1-Induced Epithelial-Mesenchymal Transition of Peritoneal Mesothelial Cells in Patients Receiving Peritoneal Dialysis.TIF by Shunyun Xie (12898211)

“…Compared with those in patients with stage 5 chronic kidney disease who are not on dialysis, serum ELA levels in patients on PD increased with the improvement of residual renal function at PD duration <36 months and decreased to pre-dialysis levels at PD duration ≥36 months, suggesting that dialysis duration is the main risk factor affecting serum ELA levels in patients on PD. …”

Neurophysiological results of patients with acromegaly. by Juan Francisco Martín-Rodríguez (399011)

“…<p>(<b>A</b>) Power spectra differences (frequency range: 1–40 Hz) among patient groups and healthy controls. …”

Data_Sheet_2_Global Burden Attributable to High Low-Density Lipoprotein-Cholesterol From 1990 to 2019.docx by Heyue Du (11229207)

“…Background<p>High low-density lipoprotein-cholesterol (LDL-C) is a public health issue contributing to ischemic heart disease (IHD) and stroke.…”

Image_2_Quercetin activates vitamin D receptor and ameliorates breast cancer induced hepatic inflammation and fibrosis.TIF by Nirmala G. Sannappa Gowda (14666519)

“…Liver enzymes activity was determined using a spectrophotometric assay. The hallmarks of inflammation and fibrosis were determined using Immunohistochemistry. …”

Appendix 3 Pre-COVID Studies BEME Virtual Interviews in Graduate Medical Education by Jennifer Westrick (13161909)

“…The optimal future state remains unclear, though a hybrid model (e.g., VIs followed by a limited number of in-person second looks) may optimize strengths and weaknesses.…”

TMEM98 is genetically downstream of MYRF. by Sarah J. Garnai (6658520)

“…<p>(A-B) Taqman qRT-PCR analysis of RPE expressed genes important for nanophthalmos (<i>Myrf</i>, <i>Best1</i>, <i>Mfrp</i>, <i>Tmem98</i>) in <i>Myrf</i>^<i>+/fl</i>, <i>RxCre;Myrf</i>^<i>+/fl</i> and <i>RxCre;Myrf</i>^<i>fl/fl</i> eyes at P3 (A) and P22 (B). …”

Supplementary Figures from AZD9496: An Oral Estrogen Receptor Inhibitor That Blocks the Growth of ER-Positive and <i>ESR1</i>-Mutant Breast Tumors in Preclinical Models by Hazel M. Weir (2123344)

“…<p>Supplementary Figure 1 contains a Western blot showing the amount of estrogen receptor remaining after treatment of MCF-7 cells with AZD9496, fulvestrant and estradiol alongside GAPDH protein levels as an internal gel loading control; Supplementary Figure 2 shows the rate of decreased detection by mass spectrometry of an estrogen receptor heavy isotype labelled peptide over time after treatment of cells with AZD9496, fulvestrant and tamoxifen and the calculated half life; Supplementary Figure 3 shows the degradation of estrogen receptor α by AZD9496, fulvestrant and estradiol in the presence of +/- 10 μM proteosomal inhibitor MG132; Supplementary Figure 4 contains a Western blot showing the re-emergence over 48 hours of estrogen receptor α following removal of AZD9496, fulvestrant and estradiol compounds from MCF-7 cells; Supplementary Figure 5 shows a bar chart of the measured estradiol levels in the blood of mice over 42 days after implantation of the mice with estrogen pellets to support growth of the MCF-7 cells as a tumour in mice; Supplementary Figure 6 shows the effects of AZD9496, fulvestrant and tamoxifen on mRNA levels of estrogen receptor regulated genes in vitro and in vivo; Supplementary Figure 7 shows the levels of estrogen receptor α protein remaining in tumours from the HCC1428 LTED model after treatment with AZD9496 and fulvestrant.…”