Image_3_Inhibition of RFX6 Suppresses the Invasive Ability of Tumor Cells Through the Notch Pathway and Affects Tumor Immunity in Hepatocellular Carcinoma.tif by Mu Song (2263654)

Analysis of Transcriptional Regulatory Pathways of Photoreceptor Genes by Expression Profiling of the <em>Otx2-</em>Deficient Retina by Yoshihiro Omori (221477)

“…We observed that expression of 101- and 1049-probe sets significantly decreased in the <em>Otx2</em> CKO retina at P1 and P12, respectively, whereas, expression of 3- and 4149-probe sets increased at P1 and P12, respectively. …”

Comparison of PCNA-Positive Cells and Percentage of Pulmonary Arterioles among the Groups. by Qing Wang (27728)

“…<p>The mean percentage of PCNA-positive cells (magnification 400×, bar = 50 μm) was significantly decreased in the AOB₆₃/ATOR₆₃ group. …”

Mu opioid agonist-induced [³⁵S]-GTPγS binding is comparable on spinal cord membrane preparation from mu-cKO and mu^fl mice. by Raphaël Weibel (458030)

“…[³⁵S]-GTPγS binding was absent on spinal cord membranes from mu-KO mice, and was decreased by half with a 50%-50% mix of membranes from mu^fl and mu-KO animals, containing half mu receptors as compared to mu^fl membranes, indicating that this assay allows to detect reduced receptor expression. …”

MEKi inhibits growth and ablates MAPK regardless of <i>PIK3CA</i>^<i>mut</i> status. by Robert S. McNeill (5485064)

“…<p>Selumetinib IC₅₀ were similar regardless of <i>PIK3CA</i>^<i>mut</i> status in NHA (<b>A</b>), but slightly higher in most <i>PIK3CA</i>^<i>mut</i> NHA^RAS compared to parental cells (*, P≤0.03) (<b>B</b>) (<b><a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0200014#pone.0200014.s011" target="_blank">S11 Fig</a></b>). …”

Table_1_Comprehensive Multi-Omics Identification of Interferon-γ Response Characteristics Reveals That RBCK1 Regulates the Immunosuppressive Microenvironment of Renal Cell Carcinom... by Wenhao Xu (2302681)

“…After RBCK1 expression was confirmed in ccRCC, we found a significantly decreased number of infiltrating CD4⁺ T cells, CD4⁺ FOXP3⁺ Treg cells, M1 macrophages, and CD56^bight/dim NK cells in the immune-cold RBCK1^high group. …”

Table 1_Accrued reductions in heart rate following transcutaneous vagal nerve stimulation in adults with posttraumatic stress disorder.docx by Srirakshaa Sundararaj (16945455)

“…Background<p>Post-Traumatic Stress Disorder (PTSD) is a condition marked by chronic autonomic dysregulation, including heightened arousal and increased heart rate, contributing to a higher risk of cardiovascular disease (CVD). tcVNS has been shown in prior work to decrease arousal and reduce heart rate in participants with PTSD during stimulation and 2–3 min afterward. …”

DataSheet_1_Comparison of the effects of monounsaturated fatty acids and polyunsaturated fatty acids on the lipotoxicity of islets.pdf by Wen Liu (39804)

“…Since comparative studies of the effects of these two types of unsaturated fatty acids (UFAs) are still limited. In this study, we aimed to compare the protective effects of various UFAs on pancreatic islets under the stress of SFA-induced metabolic disorder and lipotoxicity.…”

Hexadecenoic Fatty Acid Isomers in Human Blood Lipids and Their Relevance for the Interpretation of Lipidomic Profiles by Anna Sansone (1882819)

“…Recently, other positional and geometrical MUFA isomers belonging to the hexadecenoic family (C16 MUFA) were found in circulating lipids, such as sapienic acid (6<i>cis</i>-16:1), palmitelaidic acid (9<i>trans</i>-16:1) and 6<i>trans</i>-16:1. In this work we report: i) the identification of sapienic acid as component of human erythrocyte membrane phospholipids with significant increase in morbidly obese patients (n = 50) compared with age-matched lean controls (n = 50); and ii) the first comparison of erythrocyte membrane phospholipids (PL) and plasma cholesteryl esters (CE) in morbidly obese patients highlighting that some of their fatty acid levels have opposite trends: increases of both palmitic and sapienic acids with the decrease of linoleic acid (9<i>cis</i>,12<i>cis</i>-18:2, omega-6) in red blood cell (RBC) membrane PL were reversed in plasma CE, whereas the increase of palmitoleic acid was similar in both lipid species. …”

DataSheet_1_Exploring whole proteome to contrive multi-epitope-based vaccine for NeoCoV: An immunoinformtics and in-silico approach.docx by Shahkaar Aziz (13193277)

“…Herein, with the aid of immunoinformatics and reverse vaccinology, we aimed to formulate a multi-epitope vaccine that may be used to prevent and treat NeoCoV infection. …”

Table_1_Impact of Angiotensin-Converting Enzyme Inhibitors and Angiotensin Receptor Blockers on the Inflammatory Response and Viral Clearance in COVID-19 Patients.docx by Linna Huang (3837052)

“…<p>Objectives: To evaluate the impact of angiotensin-converting enzyme inhibitors (ACEIs) or angiotensin receptor blockers (ARBs) on the inflammatory response and viral clearance in coronavirus disease 2019 (COVID-19) patients.</p><p>Methods: We included 229 patients with confirmed COVID-19 in a multicenter, retrospective cohort study. …”

Image 2_A machine learning model to predict neurological deterioration after mild traumatic brain injury in older adults.jpeg by Daisu Abe (20498225)

“…Patients with an admission Glasgow Coma Scale (GCS) score of 12 or below or who underwent surgical treatment immediately upon admission were excluded. …”

Image_2_Changes in Local Atrial Electrograms and Surface ECG Induced by Acute Atrial Myocardial Infarction.TIF by Gerard Amorós-Figueras (5049752)

“…After 2 h of occlusion, the ECG showed a decrease in P wave amplitude (from 0.09 ± 0.04 mV to 0.05 ± 0.04 mV after 165 min occlusion, p < 0.05) and duration (64.4 ± 8.0 ms vs. 80.9 ± 12.6 ms, p < 0.01).…”

Pearson’s correlation coefficients and <i>p</i>-values. by Caitlyn Henry (18388577)

“…To explore the mechanism by which Schwann cells exert their effects in the neuron microenvironment, we investigated two main inflammatory pathways: the NF-κB and cAMP pathways, and their downstream signaling molecules. …”

Association of Baseline HbA1c With Cardiovascular and Renal Outcomes: Analyses From DECLARE-TIMI 58 by Avivit Cahn (10072991)

“…<b>Objective:</b> Current guidelines recommend prescribing SGLT-2 inhibitors to patients with type 2 diabetes and established or at high risk for atherosclerotic cardiovascular disease (ASCVD), irrespective of HbA1c levels. We studied the association of HbA1c with cardiovascular and renal outcomes and whether the benefit of dapagliflozin varies by baseline HbA1c. …”

Statistics of simulated generalized Rouse polymer chain for various connectivity in one and two sub-regions. by Ofir Shukron (3900358)

“…<i>ξ</i>_<i>E</i> = 0.12%.).</p>…”

Image_1_Voluntary Wheel Running Partially Attenuates Early Life Stress-Induced Neuroimmune Measures in the Dura and Evoked Migraine-Like Behaviors in Female Mice.TIF by Olivia C. Eller (10889103)

“…NMS was performed for 3 h/day during the first 3 weeks of life and initial observations were made at 12 weeks of age after voluntary wheel running (Exercise, -Ex) or sedentary behavior (-Sed) for 4 weeks. …”

Image_4_Changes in Local Atrial Electrograms and Surface ECG Induced by Acute Atrial Myocardial Infarction.TIFF by Gerard Amorós-Figueras (5049752)

“…After 2 h of occlusion, the ECG showed a decrease in P wave amplitude (from 0.09 ± 0.04 mV to 0.05 ± 0.04 mV after 165 min occlusion, p < 0.05) and duration (64.4 ± 8.0 ms vs. 80.9 ± 12.6 ms, p < 0.01).…”

Table_2_Sleep Disorders in Leucine-Rich Glioma-Inactivated Protein 1 and Contactin Protein-Like 2 Antibody-Associated Diseases.DOCX by Nan Lin (26755)

“…We identified status dissociatus (SD) in five (23.8%) patients with LGI1-Ab encephalitis and two (40%) patients with Caspr2-Ab diseases. …”

Data_Sheet_1_Multi-pinhole collimator design in different numbers of projections for brain SPECT.docx by Wenbo Huang (4382296)

“…</p>Methods<p>The system design was based on a commercial clinical dual-head SPECT/CT scanner, with target spatial resolutions of 12 mm and 8 mm for AD and PD SPECT, respectively. …”