Table_1_Disparities in cardiovascular disease prevalence among middle-aged and older adults: Roles of socioeconomic position, social connection, and behavioral and physiological ri... by Ji Zhang (70438)

“…Introduction<p>Cardiovascular disease (CVD) remains the leading cause of premature death globally and a major contributor to decreasing quality of life. …”

Treatment with TrkB agonists reduces food intake and weight in mice. by John C. Lin (43821)

“…<p>a, Daily IV injection of 0.6, 2 or 4 mg/kg of NT4 (n = 6 per group) resulted in dose dependent reduction in average daily food intake over 5 days in adult male DIO mice (One way ANOVA, P = 0.0098, F = 4.967 with Dunnett's posttest, P<0.01 for 4 mg/kg group compared to the vehicle group, while no statistically significant effects were observed at 0.6 or 2 mg/kg). b, Daily IV injection of 0.6, 2 or 4 mg/kg of NT4 (n = 6 per group) resulted in dose dependent reduction in body weight in adult male DIO mice (Two way ANOVA, P<0.0001 with Bonferroni's posttests, data are presented as % change relative to baseline body weight). c, Weekly IV injection of 2 mg/kg BDNF (n = 7) or NT4 (n = 7) led to significant weight loss compared to the vehicle treatment (n = 8) in adult male DIO mice at 10 days after the first dose (One way ANOVA, P = 0.002, F = 9.08 with Dunnett's posttest). d, Single IV injection of 3 mg/kg TrkB agonist monoclonal antibody (n = 7) significantly reduced body weight relative to control IgG treatment (n = 7) in adult male DIO mice 10 days after dosing (Student's t test, 2 tailed, P = 0.04). e–f, Daily treatment of Leptin receptor-deficient, 12 week old female <i>db/db</i> mice for 30 days with IV-delivered 20 mg/kg of NT4 (n = 7) decreased daily food intake by 50–80% (e), and body weight by 40% (f) relative to the vehicle treated mice (n = 8).…”

Table_4_High-Alpine Permafrost and Active-Layer Soil Microbiomes Differ in Their Response to Elevated Temperatures.xlsx by Petra Luláková (6547421)

“…Firmicutes, mainly represented by Tumebacillus and Alicyclobacillaceae OTUs, increased strongly at 40°C in active layer soils, reaching almost 50% of the total abundance. In contrast, Saccharibacteria decreased significantly with increasing temperature across all soil samples. …”

Supplementary Material for: Hepatic Oxygenation Changes and Symptomatic Intradialytic Hypotension by Ookawara S. (12076289)

“…We calculated the area under the receiver operating characteristic curve (AUC) and estimated cut-off values for changes in hepatic rSO2 as a symptomatic IDH predictor. The predictive ability at 5 and 40 min before symptomatic IDH onset was excellent, with AUCs and cut-off values of 0.847 and 0.841, and -10.9% and -5.0%, respectively. …”

Exercise-Induced Splanchnic Hypoperfusion Results in Gut Dysfunction in Healthy Men by Kim van Wijck (212826)

“…Splanchnic perfusion rapidly decreased during exercise, reflected by increased gap_g-apCO₂ from −0.85±0.15 to 0.85±0.42 kPa (p<0.001). …”

Table_3_High-Alpine Permafrost and Active-Layer Soil Microbiomes Differ in Their Response to Elevated Temperatures.xlsx by Petra Luláková (6547421)

“…Firmicutes, mainly represented by Tumebacillus and Alicyclobacillaceae OTUs, increased strongly at 40°C in active layer soils, reaching almost 50% of the total abundance. In contrast, Saccharibacteria decreased significantly with increasing temperature across all soil samples. …”

Table_1_High clinical diagnostic accuracy of combined salivary gland and myocardial metaiodobenzylguanidine scintigraphy in the diagnosis of Parkinson’s disease.DOCX by Shuangfang Li (13202799)

“…</p>Results<p>The combination of left parotid and left submandibular gland early images had a good performance in distinguishing PD from NPD, with sensitivity, specificity, and accuracy of 50.00, 94.74, and 72.37%, respectively. …”

Table_1_Yifei Sanjie Formula Treats Chronic Obstructive Pulmonary Disease by Remodeling Pulmonary Microbiota.XLSX by Yueying Wu (747404)

“…Disturbed pulmonary microbiota was discovered to involve an increased relative abundance of Ralstonia and Mycoplasma and a decreased relative abundance of Lactobacillus and Bacteroides in COPD animals. …”

Differences in H3K4Me3 enrichment between WT and <i>Mist1^−/−</i> pancreatic tissue are targeted. by Rashid Mehmood (336455)

“…(<b>B, C</b>) Schematic representation of ChIP-seq data showing H3K4Me3 enrichment for genes previously published with (<b>B</b>) decreased expression (<i>Cdkn1a</i>, <i>Rab26</i>) or (<b>C</b>) increased expression (<i>Cckar</i>) in <i>Mist1^−/−</i> (M1-) pancreatic tissue. …”

Image_1_High-Alpine Permafrost and Active-Layer Soil Microbiomes Differ in Their Response to Elevated Temperatures.TIF by Petra Luláková (6547421)

“…Firmicutes, mainly represented by Tumebacillus and Alicyclobacillaceae OTUs, increased strongly at 40°C in active layer soils, reaching almost 50% of the total abundance. In contrast, Saccharibacteria decreased significantly with increasing temperature across all soil samples. …”

Image 1_Application and validation of the machine learning-based multimodal radiomics model for preoperative prediction of lateral lymph node metastasis in papillary thyroid carcin... by Jia-Wei Feng (10754067)

“…A total of 874 ultrasound radiomics features and 1433 CT radiomics features were extracted and selected using LASSO regression. …”

data_sheet_1.docx by Rachel V. Jimenez (4910317)

“…CRP also decreased the ability of BMDCs to stimulate antigen-driven proliferation of T cells in vitro. …”

<i>In-vitro</i> antioxidant and <i>in-vivo</i> anti-aging with stress resistance on <i>Caenorhabditis elegans</i> of herbaceous peony stamen tea by Jiasong Meng (775090)

“…Moreover, PLS extracted at the same concentrations had no toxic effects on <i>C. elegans</i>, and the treatment with 1.2 mg·mL⁻¹ PLS extract significantly extended <i>C. elegans</i> lifespan that was not at the expense of reducing its reproduction and <i>Escherichia coli</i> OP50 growth. Furthermore, the same treatment extract enhanced their locomotion behavior and decreased their intestinal autofluorescence during the aging process. …”

Table1_Expression, Prognosis and Gene Regulation Network of NFAT Transcription Factors in Non-Small Cell Lung Cancer.XLSX by Jin Ma (335456)

“…High expression levels of NFAT1/2/4/5 were significantly associated with better OS in LUAD, whereas high NFAT3 expression led to a worse OS. Overexpression of NFAT1/2 predicted better OS in LUSC, whereas high NFAT5 expression led to a worse OS. …”

DataSheet_1_The Application Value of Metagenomic and Whole-Genome Capture Next-Generation Sequencing in the Diagnosis and Epidemiological Analysis of Psittacosis.zip by Zhimei Duan (10656014)

“…</p>Results<p>mNGS successfully detected the pathogen in all 16 cases (100%), while qPCR was positive only in 5 out of 10 cases (50%), indicating a significantly higher sensitivity of mNGS than qPCR (p < 0.01). …”

Table_1_Increased fruit load influences vegetative growth, dry mass partitioning, and bean quality attributes in full-sun coffee cultivation.DOCX by Andrés Felipe León-Burgos (18426216)

“…As expected, for coffee trees with a 100% fruit load, we found significant decreases in the total number of leaves, leaf area-to-fruit ratio, and branch growth; less dry mass allocated to leaves and branches with a negative correlation between this and the fruit dry mass accumulation; and lower distribution of large and healthy beans. …”

High-Level dCas9 Expression Induces Abnormal Cell Morphology in <i>Escherichia coli</i> by Suhyung Cho (60618)

“…Growth rates were severely decreased, to approximately 50% of those of wild type cells, depending on the expression levels of dCas9. …”

Data Sheet 3_Significance of LRFN4 in prognosis and tumor microenvironment of lung adenocarcinoma.xlsx by Nana Wang (533812)

“…The expressions of TCF3, E2F1, E2F3, and LRFN4 were correlated with the IC50 of multiple drugs.</p>Conclusion<p>LRFN4 may serve as a novel prognostic biomarker for LUAD, shows specific overexpression in LUAD and may be a potential therapeutic target for LUAD patients.…”

Data Sheet 1_Significance of LRFN4 in prognosis and tumor microenvironment of lung adenocarcinoma.xlsx by Nana Wang (533812)

“…The expressions of TCF3, E2F1, E2F3, and LRFN4 were correlated with the IC50 of multiple drugs.</p>Conclusion<p>LRFN4 may serve as a novel prognostic biomarker for LUAD, shows specific overexpression in LUAD and may be a potential therapeutic target for LUAD patients.…”

Table 2_Dihydromyricetin attenuates age-related macular degeneration: pharmacological effects and exploration of putative targets.docx by Hongyu Zhou (352858)

“…Introduction<p>Age-related macular degeneration (AMD) is a leading cause of vision loss in older adults, with limited effective treatments available. …”