CRISPRi conditionally knocks down transcription across hundreds of <i>Eco</i> gene targets. by Kristine L. Trotta (16447243)

“…<p><b>a) CRISPRi induction produces mild transcriptional knockdown of endogenous <i>rfp</i> (11.7-fold decrease) in <i>Eco</i>.…”

The effect of matinal active walking on cognitive, fine motor coordination task performances and perceived difficulty in 12-13 young school boys by Elghoul Yousri (6015473)

“…After each trial, a questionnaire of perceived difficulty (PD) was completed. …”

Data_Sheet_1_Evaluation of Brain Death in Laying Hens During On-Farm Killing by Cervical Dislocation Methods or Pentobarbital Sodium Injection.docx by Elein Hernandez (6678440)

“…Within 15 s after administration of pentobarbital sodium, there were significant decreases in mean frequency bands, increases in mean F50 and F95, and decreases in Ptot, suggesting brain death. …”

Data_Sheet_1_Effect of epidural spinal cord stimulation on female sexual function after spinal cord injury.docx by Claire Shackleton (13369920)

“…Sexual distress was reduced by 55%, with a mean decrease of 12 points (55.4%) from baseline (21.7 ± 17.2) to post-intervention (9.7 ± 10.8). …”

Data_Sheet_1_Effects of Different Grazing Disturbances on the Plant Diversity and Ecological Functions of Alpine Grassland Ecosystem on the Qinghai-Tibetan Plateau.docx by Wenlong Li (571749)

“…Aboveground biomass (AGB) and belowground biomass (BGB) decreased, respectively, by 41.91% (95% CI: −50.91 to −32.88%) and 17.68% (95% CI: −26.94 to −8.52%). …”

PLK2i treatment of OHSCs does not affect generation of pS129 positive aggregates, but reduces the nuclear pS129 intensity. by Sara Elfarrash (8159490)

“…Scale bars = 20 μm. b) Quantification of the amount of aggregation (aggregate area normalized to tissue area), defined by MJF-14 staining (p-value = 0.09). c-d) Quantification of the mean fluorescence intensity of α-syn aggregates detected with MJF-14 (c, p-value = 0.712) and aggregate-specific pS129 that overlaps with MJF-14 (d, p-value = 0.214). e) Quantification of nuclear (non-aggregate related) pS129, illustrating a significant decrease in mean fluorescence intensity following PLK2i-treatment (p-value = 0.0087). f) Relative ratio of aggregate-specific pS129/nuclear pS129 in PFF-injected slices shows an increase of ratio of the signals of aggregates/background following PLK2i treatment, due to reduction of the non-aggregate-related nuclear pS129-signal (p-value = 0.009). …”

Sample details and genome coverage (n = 1,409). by Mathieu Vanhove (3298326)

Flavonoid biosynthesis pathway and the key genes along it. by Gustavo Roberto Fonseca de Oliveira (10739500)

AAV-hGATA-enhanced GFP (eGFP) vector construction and expression in the hippocampal neurons. by Miyeon Choi (648726)

“…CUS animals injected with KET showed a decrease in rGATA-2 mRNA compared with CUS animals (<i>P</i><0.05; <i>n</i> = 6 animals in each group). …”

Examining cardiac toxicity in HER2-positive breast cancer patients using trastuzumab and its influencing factors at Iran Hospital by Fatemeh Nasri (8290011)

“…The criteria for heart failure in this study were defined as an ejection fraction (EF) of less than 50% or a decrease of greater than 10% in EF. Descriptive statistics, the chi-square statistical test, Fisher’s exact test, and logistic regression analyses were employed to assess the variables. …”

Let-7b targets at TLR4 and regulates TLR4 expression via post-transcriptional suppression. by Gui-gen Teng (380044)

“…A dose-dependent decrease of TLR4 protein was determined with let-7b mimics treatment. …”

Results of mechanical analysis of SA and PLGA MN. by Yusuf K. Demir (475556)

“…MN failure was interpreted as the sudden decrease in force. (B) Mechanical analysis of polymeric PLGA (50∶50) MNs under axial loading. …”

GHG emissions along the baseline for different regions and sources by H Valin (557174)

“…Our results confirm that yield increase could mitigate some agriculture-related emissions growth over the next decades. Closing yield gaps by 50% for crops and 25% for livestock by 2050 would decrease agriculture and land use change emissions by 8% overall, and by 12% per calorie produced. …”

Human glaucomatous trabecular cells produce SDF-1(5-67). by Alexandre Denoyer (160189)

“…MMP inhibitors batimastat (100 nM) and TIMP-1 (0.5 nM) induce a decrease in SDF-1(5-67) production, whereas TNF-α (50 ng/mL [2.9 nM]) and TGF-β2 (10 ng/mL [0.8 nM]) enhance the production of SDF-1(5-67). ** <i>P</i><0.01. …”

Image_1_Cardiac resynchronization therapy in heart failure patients by using left bundle branch pacing.TIF by Ying Gu (203149)

“…</p>Results<p>Left bundle branch pacing was successful in all 34 patients (mean age 65.6 ± 11.2 years, 67.6% men). A significant decrease in QRS duration (QRSd) was observed after the LBBP operation for 1 month (153.2 ± 1.7 vs. 111.9 ± 2.6 ms, p < 0.01). …”

AS101 attenuates high glucose induced mesangial cell proliferation. by Itay Israel Shemesh (669254)

“…OD levels were compared to control which was normalized to 100%. Results represent mean±SEM from three experiments. #p<0.05 decrease vs. …”

Nilotinib inhibits cell viability and neurosphere formation in medulloblastoma cells (MB-PDX and DAOY). by Kirti Kandhwal Chahal (7411091)

“…Nilotinib was observed to be most potent in inhibiting the formation of NS from single cells. (<b>f)</b> A representative Western blot for quantitation of nuclear Gli-1 in MB-PDX and DAOY cells shows a decrease in Gli-1 protein after treatment with 5 μM Nilotinib for 24 hours. …”

ErbB signaling is implicated in generation of neurons and mitoses in the sub-ventricular zone. by Tomomi Sato (301255)

“…Impaired neurogenesis and a decrease in pH3-positive mitotic cells in the SVZ of AG1478-treated Tg(<i>pou4f1-hsp70l</i>:<i>GFP;-8</i>.…”

Table_1_Morphological characterization, pathogenicity screening, and molecular identification of Fusarium spp. isolates causing post-flowering stalk rot in maize.DOCX by J. Harish (14950603)

“…Pathogenicity test during the Kharif season showed 12 isolates with virulent disease symptoms with a mean severity ranging between 50 to 67 percent disease index (PDI) whereas in Rabi season, only five isolates were considered virulent, and the mean severity ranged between 52 to 67 PDI. …”

Validation of complete model with trafficking and phosphorylation parameters. by Lindsay Wendel Clegg (754229)

“…TIME cells, [V] = 50 ng/mL, measurements taken at t = 5 min. In the model, the experimentally observed decrease in VEPTP expression to 20% of control values with VEPTP siRNA was simulated by decreasing the dephosphorylation rate for Y951 and Y1175 by a factor of 5 on the cell surface. …”