Trends in alcohol and tobacco use among Brazilian students: 1989 to 2010 by Zila M Sanchez (4656289)

“…<div><p> OBJECTIVE To analyze temporal trends of the prevalence of alcohol and tobacco use among Brazilian students. METHODS We analyzed data published between 1989 and 2010 from five epidemiological surveys on students from the 6th to the 12th grade of public schools from the ten largest state capitals of Brazil. …”

DHPG-induced long-term depression is not dependent on protein synthesis or mammalian Target of Rapamycin in <i>Cyfip1</i> heterozygotes. by Ozlem Bozdagi (144573)

“…<p>(<b>A</b>) LTD was induced by DHPG (50 µM for 5 minutes, indicated by the short horizontal bar) in hippocampal slices from wildtype (Wt) and <i>Cyfip1</i> heterozygous (Het) mice. …”

Characterization of ear defects in <i>β-tectorin</i> morphants. by Chung-Hsiang Yang (211530)

“…<p>The expression levels of the following inner ear marker genes, such as starmaker (<i>stm</i>) (A), otolith matrix protein 1 (<i>omp-1</i>) (B), and zona pellucida-like domain-containing protein-like 1 (<i>zpDL1</i>) (C), were examined by whole-mount <i>in situ</i> hybridization in <i>β-tectorin</i> morphants. …”

Concentration-response analysis of native <i>Eg</i>KU-1 on ASIC currents from DRG neurons. by Martín Fló (169408)

“…<p>(A) Analysis of native <i>Eg</i>KU-1 inhibitory effect on the ASIC current amplitude (n = 26). …”

Emodin counteracts high glucose (HG)-induced growth in rat mesangial cells (MCs). by Junjie Gao (545578)

“…<p>(<b>a</b>) MTT assay shows HG but not mannitol promotes cell growth of high-passage MCs, the growth can be effectively arrested by 50 μM emodin. …”

Lifespan analysis of <i>C. elegans</i> strains in the presence of TCA cycle intermediates. by Clare B. Edwards (385682)

“…<p>10 mM concentrations of malate, succinate, or fumarate were present where indicated. (<b>A</b>) Malate (log-rank <i>p</i><0.001) or fumarate (log-rank <i>p</i><0.001), but not succinate (log-rank <i>p</i> = 0.72) extended lifespan of N2 worms. …”

Dose response inhibition of IP6K1 by TNP in the presence of different concentrations of ATP and IP6. by Michael Wormald (4631122)

“…<p>TNP was confirmed to compete with ATP by binding to IP6K1. (A) IC₅₀ values increased from 12±1.1μM to 39±1.1μM when ATP concentrations increased from 62.5μM to 2000μM indicating competitive inhibition. …”

BPA toxicity during development of zebrafish embryo by C. F. V. Scopel (10405044)

“…In this study we evaluated the toxicity of bisphenol A in zebrafish embryos (Danio rerio) and determined the 50% lethal concentration (LC50) of this chemical. …”

Processing of V3Nter releases FZC18. by Delphine Quélard (43727)

“…</i> By contrast, in medium <i>(M),</i> a 36 kD polypeptide predominates and the 80 kD form decreases in intensity. …”

Table3_Effects of Acute Exposure to Polystyrene Nanoplastics on the Channel Catfish Larvae: Insights From Energy Metabolism and Transcriptomic Analysis.XLSX by Qichen Jiang (381183)

“…Activities of most metabolic enzymes analyzed decreased in the larvae after 48 h of exposure, especially in 25 or 50 mg/L of PS-NPs. …”

Image1_Effects of Acute Exposure to Polystyrene Nanoplastics on the Channel Catfish Larvae: Insights From Energy Metabolism and Transcriptomic Analysis.TIF by Qichen Jiang (381183)

“…Activities of most metabolic enzymes analyzed decreased in the larvae after 48 h of exposure, especially in 25 or 50 mg/L of PS-NPs. …”

Table2_Effects of Acute Exposure to Polystyrene Nanoplastics on the Channel Catfish Larvae: Insights From Energy Metabolism and Transcriptomic Analysis.XLSX by Qichen Jiang (381183)

“…Activities of most metabolic enzymes analyzed decreased in the larvae after 48 h of exposure, especially in 25 or 50 mg/L of PS-NPs. …”

Table1_Effects of Acute Exposure to Polystyrene Nanoplastics on the Channel Catfish Larvae: Insights From Energy Metabolism and Transcriptomic Analysis.DOCX by Qichen Jiang (381183)

“…Activities of most metabolic enzymes analyzed decreased in the larvae after 48 h of exposure, especially in 25 or 50 mg/L of PS-NPs. …”

Crosstalk between lysine methylation and phosphorylation of ATG16L1 dictates the apoptosis of hypoxia/reoxygenation-induced cardiomyocytes by Huiwen Song (755791)

“…Furthermore, we validate that this methylation at lysine 151 impairs the binding of ATG16L1 to the ATG12–ATG5 conjugate, leading to inhibition of autophagy and increased apoptosis in H/R-treated cardiomyocytes. …”

Data_Sheet_2_Environmental carcinogens disproportionally mutate genes implicated in neurodevelopmental disorders.docx by Brennan H. Baker (6102506)

“…</p>Methods<p>To explore environmental mutation vulnerability of disease-associated gene sets, we analyzed publicly available whole genome sequencing datasets of mutations in human induced pluripotent stem cell clonal lines exposed to 12 classes of environmental carcinogens, and human lung cancers from individuals living in highly polluted regions. …”

Table_1_A Transcriptomic Model of Postnatal Cardiac Effects of Prenatal Maternal Cortisol Excess in Sheep.pdf by Andrew Antolic (6906836)

“…In order to model corticosteroid effects in the neonate, we created a second model in which cortisol was infused for 12 h per day for a daily infusion of 0.5 mg/kg/d. …”

DNA Methyltransferase Inhibitor Zebularine Induces Human Cholangiocarcinoma Cell Death through Alteration of DNA Methylation Status by Kazuaki Nakamura (104267)

“…DNA methylation analysis demonstrated that zebularine induced DNA demethylation, and the GO Biological Process terms “hemophilic cell adhesion”, “regulation of transcription, DNA-dependent” and “Wnt signaling pathway” were found to be significantly enriched in association with demethylated genes. Furthermore, we observed that zebularine treatment decreased β-catenin protein levels in TFK-1 and HuCCT1 cells. …”

Table_3_A Transcriptomic Model of Postnatal Cardiac Effects of Prenatal Maternal Cortisol Excess in Sheep.pdf by Andrew Antolic (6906836)

“…In order to model corticosteroid effects in the neonate, we created a second model in which cortisol was infused for 12 h per day for a daily infusion of 0.5 mg/kg/d. …”

Table_2_A Transcriptomic Model of Postnatal Cardiac Effects of Prenatal Maternal Cortisol Excess in Sheep.pdf by Andrew Antolic (6906836)

“…In order to model corticosteroid effects in the neonate, we created a second model in which cortisol was infused for 12 h per day for a daily infusion of 0.5 mg/kg/d. …”

Data_Sheet_1_Oral Administration of Heat-Treated Lactobacilli Modifies the Murine Microbiome and Reduces Citrobacter Induced Colitis.docx by Alicja K. Warda (8377566)

“…Extended consumption of the ADR-159 diet had no negative effect on general health and lipocalin 2 levels (LCN2; a proxy for inflammation), but we observed increased IL-17f and decreased IL-12α expression in the colon and decreased short chain fatty acid levels in the ADR-159 fed animals. …”