Table_1_The Immunologic Effect of Early Intravenous Two and Four Gram Bolus Dosing of Tranexamic Acid Compared to Placebo in Patients With Severe Traumatic Bleeding (TAMPITI): A Ra... by Philip C. Spinella (5181788)

“…</p>Methods<p> This was a single center, double-blinded, randomized controlled trial (RCT) comparing placebo to a 2 g or 4 g intravenous TXA bolus dose in trauma patients with severe injury. …”

DataSheet1_Ginkgo Biloba Extract Is Comparable With Donepezil in Improving Functional Recovery in Alzheimer’s Disease: Results From a Multilevel Characterized Study Based on Clinic... by Yu Zheng (2950)

Table_1_Campylobacter Colonization, Environmental Enteric Dysfunction, Stunting, and Associated Risk Factors Among Young Children in Rural Ethiopia: A Cross-Sectional Study From th... by Dehao Chen (4966207)

“…<p>Livestock farming provides a possible mechanism by which smallholder farmers can meet their household need for animal source foods (ASF), which may reduce the risk of stunting. …”

Different Phenotypes of the Two Chinese Probands with the Same c.889G>A (p.C162Y) Mutation in <i>COCH</i> Gene Verify Different Mechanisms Underlying Autosomal Dominant Nonsyndromi... by Qi Wang (22418)

“…The results presented bilateral sensorineural hearing loss with a decreasing pattern, involving the low frequencies. …”

Maximum likelihood phylogeny inferred from an alignment of single-nucleotide polymorphisms present in the core genome of 937 isolates obtained from a subset of 3 studies of pneumoc... by Taj Azarian (659326)

Data_Sheet_1_Comparison of Postnatal Growth Charts of Singleton Preterm and Term Infants Using World Health Organization Standards at 40–160 Weeks Postmenstrual Age: A Chinese Sing... by Li Zhang (8200)

“…The Z-scores for length/height, weight, and BMI of preterm infants relative to the WHO standards gradually decreased from 1.20, 1.13, and 0.74 at 40–44 weeks PMA to 0.67, 0.42, and 0.03 at 132–160 weeks PMA, respectively; Z-scores for HC of preterm infants rapidly decreased from 0.73 to 0.29 at 40–50 weeks PMA, and then fluctuated in the range of 0.08–0.23 at 50–160 weeks PMA. …”

Table_1_Neurophysiological and Neuroradiological Changes in Children With Chronic Kidney Disease.XLSX by Sameh A. Abd El Naby (9645500)

“…</p><p>Methods: The study included 50 patients with CKD admitted to a pediatric nephrology unit. …”

Computational simulations assessment of mutations impact on streptokinase (SK) from a group G <i>streptococci</i> with enhanced activity – insights into the functional roles of str... by Faegheh Kazemi (5298311)

Table_1_HLA-A*11:01:01:01, HLA-C*12:02:02:01-HLA-B*52:01:02:02, Age and Sex Are Associated With Severity of Japanese COVID-19 With Respiratory Failure.xlsx by Seik-Soon Khor (7244753)

“…After multivariate analysis controlling for other confounding factors and comorbidities, HLA-A*11:01:01:01 [P = 3.34E-03, OR = 3.41 (1.50–7.73)], age at diagnosis [P = 1.29E-02, OR = 1.04 (1.01–1.07)] and sex at birth [P = 8.88E-03, OR = 2.92 (1.31–6.54)] remained significant. …”

Image_2_The novel chimeric multi-agonist peptide (GEP44) reduces energy intake and body weight in male and female diet-induced obese mice in a glucagon-like peptide-1 receptor-depe... by James E. Blevins (11405813)

“…We hypothesized that GEP44 reduces energy intake and BW primarily through a GLP-1R dependent mechanism. To test this hypothesis, GLP-1R^+/+ mice and GLP-1R null (GLP-1R^-/-) mice were fed a high fat diet for 4 months to elicit diet-induced obesity prior to undergoing a sequential 3-day vehicle period, 3-day drug treatment (5, 10, 20 or 50 nmol/kg; GEP44 vs the selective GLP-1R agonist, exendin-4) and a 3-day washout. …”

Image_1_The novel chimeric multi-agonist peptide (GEP44) reduces energy intake and body weight in male and female diet-induced obese mice in a glucagon-like peptide-1 receptor-depe... by James E. Blevins (11405813)

“…We hypothesized that GEP44 reduces energy intake and BW primarily through a GLP-1R dependent mechanism. To test this hypothesis, GLP-1R^+/+ mice and GLP-1R null (GLP-1R^-/-) mice were fed a high fat diet for 4 months to elicit diet-induced obesity prior to undergoing a sequential 3-day vehicle period, 3-day drug treatment (5, 10, 20 or 50 nmol/kg; GEP44 vs the selective GLP-1R agonist, exendin-4) and a 3-day washout. …”

Basal levels of (A) C/EBP-α, (B) GLUT4, (C) S100B, (D) PPAR-α, (E) PPAR-β/δ, (F) PPAR-γ, (G) TSPO, (H) PKCε mRNAs normalized to RPS18. by Enrico Campioli (336888)

Transfection efficiency corrected ³H-gemcitabine uptake in HEK293 (A), AsPC-1 (B), and MIA PaCa-2 (C) cells with or without transfection of hCNT3 cDNA. by Robert J. Paproski (282968)

“…Uptake values were corrected for transfection efficiency as described in the <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0056423#s2" target="_blank">methods</a> section. …”

Gene expression of <i>Iex-1</i> and <i>Vegf-A</i> by qRT-PCR in outflow vein of AVF seven days after adventitial delivery of hydrogel alone, hydrogel with nanoparticle PLGA without... by Akshaar Brahmbhatt (551498)

DataSheet1_Pharmacokinetic herb-drug interactions: Altered systemic exposure and tissue distribution of ciprofloxacin, a substrate of multiple transporters, after combined treatmen... by Ziqiang Li (247218)

“…</p><p>Results: Concurrent use of PCE substantially reduced circulating CIP (approximately 40%–50%) in humans and rats, while CIP hardly changed circulating GA and PCA. …”

DataSheet2_Pharmacokinetic herb-drug interactions: Altered systemic exposure and tissue distribution of ciprofloxacin, a substrate of multiple transporters, after combined treatmen... by Ziqiang Li (247218)

“…</p><p>Results: Concurrent use of PCE substantially reduced circulating CIP (approximately 40%–50%) in humans and rats, while CIP hardly changed circulating GA and PCA. …”

DataSheet_1_Insulin-like growth factor binding protein 5b of Trachinotus ovatus and its heparin-binding motif play a critical role in host antibacterial immune responses via NF-κB... by Hehe Du (14612936)

Data_Sheet_1_Partial Inhibition of the 6-Phosphofructo-2-Kinase/Fructose-2,6-Bisphosphatase-3 (PFKFB3) Enzyme in Myeloid Cells Does Not Affect Atherosclerosis.docx by Renée J. H. A. Tillie (11264361)

“…Pfkfb3^wt/wt and Pfkfb3^fl/fl mice were fed a 0.25% cholesterol diet for 12 weeks. Pfkfb3^fl/fl bone marrow-derived macrophages (BMDMs) showed 50% knockdown of Pfkfb3 mRNA. …”

Light-intensity dependence of net oxygen production and consumption, as measured with a membrane-inlet mass spectrometer (MIMS), of wild type <i>Synechocystis</i>, its ΔOx and ΔFlv... by R. Milou Schuurmans (798363)

“…Experiments with <i>Synechocystis</i> and its mutant derivatives were conducted at 18°C and <i>Chlorella</i> at 30°C. ●, oxygen evolution measured as an increase in the concentration of ³²O₂; ◊, oxygen uptake measured as a decrease in the concentration of ³⁶O₂; Δ, net rate of photosynthesis (i.e. rate of net oxygen evolution + rate of oxygen uptake). …”

DataSheet1_Greater than recommended stiffness and power setting of a stance-phase powered leg prosthesis can improve step-to-step transition work and effective foot length ratio du... by Joshua R. Tacca (18067213)

“…People with TTA using a stance-phase powered prosthesis (e.g., BiOM, Ottobock, Duderstadt, Germany) walk with increased AL_trail W_pos and potentially decreased magnitude of UL_lead W_neg compared to a passive-elastic prosthesis. …”