Basal ECD mutations have the greatest influence on activation. by Ákos Nemecz (356830)

“…<p>Stick representation of the evaluated Asp, Glu, and His residues are labeled and color coded based upon effect, with residues in red producing significant decrease in pH₅₀ as a single mutation, in pink a significant decrease in combination, in yellow an insignificant or weak effect, and in blue a significant increase in pH₅₀. …”

The impact of alternative therapies. by Elsa Hansen (3737224)

Comparison between OFF responses predicted by our model and neurobiological data. by Ulysse Rançon (15451568)

“…<p>Experimental measurements were performed in the mouse medial geniculate body (MGB) and anterior auditory field (AAF)(see [<a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1012288#pcbi.1012288.ref012" target="_blank">12</a>]). …”

Effect of afferent and inhibitory plasticity. by Giacomo Spigler (3249840)

Ten years of antiretroviral therapy: Incidences, patterns and risk factors of opportunistic infections in an urban Ugandan cohort by Dana Weissberg (5921303)

“…In patients developing OIs at a current CD4 cell count >200 cells/μL, factors independently associated with OI development were time-varying increase in viral load and time-varying decrease in hemoglobin, whereas a baseline CD4 cell count <50 cells/μL was protective.…”

Relationship between abundance of Woody Plants, Animal and Plant Species by Geethanjanen Raveendhran (3113937)

“…This process was done every 2 m along the transect 25 times in the woodlot/forest. For data set 3, we stood at the beginning of the transect and surveyed along a 50 m radius for 15 minutes (trial 1) and observed the abundance of humans that crossed by, without including lab group members. …”

Table_1_Persistence of Antibodies Against Spike Glycoprotein of SARS-CoV-2 in Healthcare Workers Post Double Dose of BBV-152 and AZD1222 Vaccines.DOCX by Hari Ram Choudhary (10884963)

“…</p><p>Conclusion: This 6-month follow-up study documents a 2-fold and 4-fold decrease in spike antibody titer among Covishield and Covaxin recipients, respectively. …”

The protective effects of Mirtazapine against lipopolysaccharide (LPS)-induced brain vascular hyperpermeability by Yuehong Pu (12006646)

“…In the <i>in vitro</i> assay, bEnd.3 brain endothelial cells were treated with 1 μM LPS in the absence or presence of Mirtazapine (25, 50 μM). We found that LPS-treated cells had significantly declined transendothelial electrical resistance (TEER), increased monolayer permeability, elevated production of inflammatory factors, and downregulated ZO-1. …”

DataSheet_1_Severity Level and Duration of Energy Deficit in Mice Affect Bone Phenotype and Bone Marrow Stromal Cell Differentiation Capacity.docx by Viktorija Avilkina (9603833)

“…BMSCs extracted from 12% and 18% SBA groups showed a significant decrease in Sirt1 mRNA levels before and after co-differentiation. …”

Data_Sheet_1_Excess Mortality in Italy During the COVID-19 Pandemic: Assessing the Differences Between the First and the Second Wave, Year 2020.PDF by Maria Dorrucci (252694)

“…The models were also applied to estimate all-cause excess deaths “not directly attributable to COVD-19”, i.e., without a previous COVID-19 diagnosis. During the first wave (25th February−31st May), we estimated 52,437 excess deaths (95% CI: 49,213–55,863) and 50,979 (95% CI: 50,333–51,425) during the second phase (10th October−31st December), corresponding to percentage 34.8% (95% CI: 33.8%–35.8%) in the second wave and 31.0% (95%CI: 27.2%–35.4%) in the first. …”

Data_Sheet_2_Excess Mortality in Italy During the COVID-19 Pandemic: Assessing the Differences Between the First and the Second Wave, Year 2020.PDF by Maria Dorrucci (252694)

“…The models were also applied to estimate all-cause excess deaths “not directly attributable to COVD-19”, i.e., without a previous COVID-19 diagnosis. During the first wave (25th February−31st May), we estimated 52,437 excess deaths (95% CI: 49,213–55,863) and 50,979 (95% CI: 50,333–51,425) during the second phase (10th October−31st December), corresponding to percentage 34.8% (95% CI: 33.8%–35.8%) in the second wave and 31.0% (95%CI: 27.2%–35.4%) in the first. …”

Table_1_Secondary Outcomes of Implemented Depression Prevention in Adolescents: A Randomized Controlled Trial.DOCX by Karlijn W. J. de Jonge-Heesen (10181135)

“…We conducted exploratory analyses in 130 adolescents with elevated depressive symptoms aged between 12 and 16 years old (M = 13.59; SD = 0.68; 63.8% girls) who were randomly assigned to the experimental (OVK 2.0) or active control condition (psycho-education). …”

Image_1_Secondary Outcomes of Implemented Depression Prevention in Adolescents: A Randomized Controlled Trial.PNG by Karlijn W. J. de Jonge-Heesen (10181135)

“…We conducted exploratory analyses in 130 adolescents with elevated depressive symptoms aged between 12 and 16 years old (M = 13.59; SD = 0.68; 63.8% girls) who were randomly assigned to the experimental (OVK 2.0) or active control condition (psycho-education). …”

Synaptic efficacy is reduced during UP states. by Brendon O. Watson (268774)

“…In purple are EPSP percent changes for 4 recorded interneurons, which show heterogeneous changes during the UP state ranging from a 30% increase to a 65% decrease (mean: 26.5% decrease, standard deviation 50.0%; see gray bar at left of graph). …”

Image_1_The Impact of Multimorbidity Burden, Frailty Risk Scoring, and 3-Directional Morphological Indices vs. Testing for CSF Responsiveness in Normal Pressure Hydrocephalus.JPEG by Shereen X. Y. Soon (9569062)

“…This was due to a significant decrease in ventricular measurement (p = 0.005) that correlated to independent 3D volumetry (p = 0.008).…”

Data_Sheet_1_Inhibiting methanogenesis by targeting thermodynamics and enzymatic reactions in mixed cultures of rumen microbes in vitro.PDF by Kairi Tanaka (19418200)

“…Here, we provide a proof of concept that the combination of an electron acceptor and a methane analog may be exploited to improve microbial efficiency via methanogenesis inhibition.…”

The effect of Andro alone or in combination with Taxi on MMP loss in HeLa cells. by Mazen Alzaharna (3737878)

“…(E) A representative flow cytometric histograms showing the loss in MMP (decrease in FL2 fluorescence) in HeLa cells treated with 50 μM Andro and/or 100 μM Taxi for 24 or 48 h and stained with JC-1. …”

CK2α Inhibition Down-Regulates Gli1 Expression and Transcriptional Activity. by Shulin Zhang (154810)

“…In protein level, these decreases rose to 76% (10 µM CX-4945) and 89% (50 µM TBB) in A549, and 81% (10 µM CX-4945) and 93% (50 µM TBB) in H1299, respectively. …”

Randomized, Controlled Trial of Therapy Interruption in Chronic HIV-1 Infection by Emmanouil Papasavvas (5406)

“…Based on these findings, we suggest that further clinical research on the long-term consequences of TI strategies to decrease drug exposure is warranted.…”

Proliferation of CTS-treated cells. by Rebecca J. Clifford (497197)

“…<p>A) Normal MCF10A cells exhibited a concentration-dependent decrease in BrdU incorporation (proliferation) when treated with 500 nM ouabain, 50 nM bufalin or 100 nM bufalin for 2 hours (p<0.01). …”