DataSheet_1_Tuning Scorpion Toxin Selectivity: Switching From KV1.1 to KV1.3.docx by Andrei M. Gigolaev (9090713)

“…Despite several decades of research the molecular determinants of KTx selectivity are still poorly understood. Here we analyze MeKTx13-3 (Kalium ID: α-KTx 3.19) from the lesser Asian scorpion Mesobuthus eupeus, a high-affinity K_V1.1 blocker (IC₅₀ ~2 nM); it also affects K_V1.2 (IC₅₀ ~100 nM), 1.3 (~10 nM) and 1.6 (~60 nM). …”

A voxel-based morphometry study of Tourette syndrome by Charissa F. Black (385267)

“…No significant results after correction for multiple comparisons; trend decrease in GM concentration in voxels centered in left precentral gyrus (primary motor cortex) (-26, -12, 66).…”

Expression of BDNF in retinas after 6 weeks of diabetes onset in SE- or EE-housed animals. by Damián Dorfman (293002)

“…<p>In animals housed in SE a decrease in BDNF immunostaining in both inner and outer retina was observed, whereas in retinas from diabetic animals housed in EE, BDNF expression was similar to control animals kept in SE or EE. …”

Evaluation of HH target gene mRNA and protein expression following vismodegib treatment of canine OSA cell lines. by Vincent E. Baldanza (8781671)

“…<p>(A) The cell lines demonstrated variable decreases in some target genes at the transcript level with treatment at the determined IC₅₀ value when compared to vehicle control (DMSO) treatment. …”

Effects of Gβ5 and Gβ1 coexpression on agonist-induced receptor internalization. by J. Christopher Octeau (622081)

“…<p><b>A.</b> Quantification of the relative levels of transiently expressed cell surface D2R in HEK293 cells expressing D2R alone, D2R and Gβ1 or D2R and Gβ5, after treatment of with dopamine (50 µM for 45 min). …”

Reduction of LZTFL1 activity restores BBSome ciliary trafficking in BBS3 and BBS5 depleted cells. by Seongjin Seo (198289)

Histological sections and Mankin score of rabbit cartilages also showed OA change at 2 weeks. by Kohei Nishitani (526108)

“…<p>A) OA change such as fibrillation of the surface and decrease of safranin/O stainingwas detected from 2 weeks and deteriorated overtime. …”

ANALYSIS OF MASTER SWIMMERS’ SPORT PERFORMANCE FOR DIFFERENT FREESTYLE DISTANCES by André Geraldo Brauer Júnior (5311607)

“…<div><p>ABSTRACT The aim of this study was to analyze the decline rate of master swimmers’ world records compared to absolute world records, and sport performance decrease for both genders and different age groups (25 to 99 years old) in 50, 400 and 1500 meters freestyle swimming. …”

Table_2_Effect of Prophylactic Levosimendan on All-Cause Mortality in Pediatric Patients Undergoing Cardiac Surgery—An Updated Systematic Review and Meta-Analysis.DOC by Hongbai Wang (9241985)

“…<p>Background: Levosimendan, a calcium sensitizer, enhances the myocardial function by generating more energy-efficient myocardial contractility than that achieved through adrenergic stimulation with catecholamines. We conducted this meta-analysis to primarily investigate the effects of levosimendan on all-cause mortality in pediatric patients undergoing cardiac surgery under cardiopulmonary bypass.…”

Table_1_Effect of Prophylactic Levosimendan on All-Cause Mortality in Pediatric Patients Undergoing Cardiac Surgery—An Updated Systematic Review and Meta-Analysis.DOC by Hongbai Wang (9241985)

“…<p>Background: Levosimendan, a calcium sensitizer, enhances the myocardial function by generating more energy-efficient myocardial contractility than that achieved through adrenergic stimulation with catecholamines. We conducted this meta-analysis to primarily investigate the effects of levosimendan on all-cause mortality in pediatric patients undergoing cardiac surgery under cardiopulmonary bypass.…”

Table_4_Effect of Prophylactic Levosimendan on All-Cause Mortality in Pediatric Patients Undergoing Cardiac Surgery—An Updated Systematic Review and Meta-Analysis.DOC by Hongbai Wang (9241985)

“…<p>Background: Levosimendan, a calcium sensitizer, enhances the myocardial function by generating more energy-efficient myocardial contractility than that achieved through adrenergic stimulation with catecholamines. We conducted this meta-analysis to primarily investigate the effects of levosimendan on all-cause mortality in pediatric patients undergoing cardiac surgery under cardiopulmonary bypass.…”

Table_3_Effect of Prophylactic Levosimendan on All-Cause Mortality in Pediatric Patients Undergoing Cardiac Surgery—An Updated Systematic Review and Meta-Analysis.DOC by Hongbai Wang (9241985)

“…<p>Background: Levosimendan, a calcium sensitizer, enhances the myocardial function by generating more energy-efficient myocardial contractility than that achieved through adrenergic stimulation with catecholamines. We conducted this meta-analysis to primarily investigate the effects of levosimendan on all-cause mortality in pediatric patients undergoing cardiac surgery under cardiopulmonary bypass.…”

Image_2_Effect of Prophylactic Levosimendan on All-Cause Mortality in Pediatric Patients Undergoing Cardiac Surgery—An Updated Systematic Review and Meta-Analysis.TIF by Hongbai Wang (9241985)

“…<p>Background: Levosimendan, a calcium sensitizer, enhances the myocardial function by generating more energy-efficient myocardial contractility than that achieved through adrenergic stimulation with catecholamines. We conducted this meta-analysis to primarily investigate the effects of levosimendan on all-cause mortality in pediatric patients undergoing cardiac surgery under cardiopulmonary bypass.…”

Image_1_Effect of Prophylactic Levosimendan on All-Cause Mortality in Pediatric Patients Undergoing Cardiac Surgery—An Updated Systematic Review and Meta-Analysis.TIF by Hongbai Wang (9241985)

“…<p>Background: Levosimendan, a calcium sensitizer, enhances the myocardial function by generating more energy-efficient myocardial contractility than that achieved through adrenergic stimulation with catecholamines. We conducted this meta-analysis to primarily investigate the effects of levosimendan on all-cause mortality in pediatric patients undergoing cardiac surgery under cardiopulmonary bypass.…”

Imported malaria in the UK, 2005 to 2016: Estimates from primary care electronic health records by Hamad Bastaki (5881133)

“…</p><p>Setting</p><p>UK primary care</p><p>Participants</p><p>In total, we examined 12,349,003 individuals aged 0 to 99 years.…”

Potent Metabolic Sialylation Inhibitors Based on C‑5-Modified Fluorinated Sialic Acids by Torben Heise (1507726)

Image_4_Brucella abortus BspJ Is a Nucleomodulin That Inhibits Macrophage Apoptosis and Promotes Intracellular Survival of Brucella.JPEG by Zhongchen Ma (9631427)

Image_2_Brucella abortus BspJ Is a Nucleomodulin That Inhibits Macrophage Apoptosis and Promotes Intracellular Survival of Brucella.JPEG by Zhongchen Ma (9631427)

Image_3_Brucella abortus BspJ Is a Nucleomodulin That Inhibits Macrophage Apoptosis and Promotes Intracellular Survival of Brucella.JPEG by Zhongchen Ma (9631427)

Dynamic-SERS Optophysiology: A Nanosensor for Monitoring Cell Secretion Events by Félix Lussier (1749676)