Showing 1,701 - 1,720 results of 47,911 for search '(( 12 we decrease ) OR ( 50 ((((nn decrease) OR (teer decrease))) OR (a decrease)) ))', query time: 0.80s Refine Results
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    A conceptual summary of the current study. by Jumpei Yamashita (11450146)

    Published 2021
    “…The long-term increase in the overall RT is interpreted as a decrement in long-term vigilance. The underlying mechanism of this relationship could be ANS-related tonic activity of the LC from 0.1 to 5.0 Hz. …”
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  7. 1707

    Discovery of Novel Oxazepine Derivatives as Akt/ROCK Inhibitors for Growth Arrest and Differentiation Induction in Neuroblastoma Treatment by Jinxin Che (791250)

    Published 2023
    “…Evidence suggests that targeted inhibitors may provide opportunities for inducing neuroblastoma differentiation while inhibiting proliferation. Here, we demonstrate the synergistic effect of inhibiting Akt and ROCK in antineuroblastoma and present the design and discovery of a new Akt/ROCK inhibitor, <b>B12</b>. …”
  8. 1708

    Discovery of Novel Oxazepine Derivatives as Akt/ROCK Inhibitors for Growth Arrest and Differentiation Induction in Neuroblastoma Treatment by Jinxin Che (791250)

    Published 2023
    “…Evidence suggests that targeted inhibitors may provide opportunities for inducing neuroblastoma differentiation while inhibiting proliferation. Here, we demonstrate the synergistic effect of inhibiting Akt and ROCK in antineuroblastoma and present the design and discovery of a new Akt/ROCK inhibitor, <b>B12</b>. …”
  9. 1709

    Discovery of Novel Oxazepine Derivatives as Akt/ROCK Inhibitors for Growth Arrest and Differentiation Induction in Neuroblastoma Treatment by Jinxin Che (791250)

    Published 2023
    “…Evidence suggests that targeted inhibitors may provide opportunities for inducing neuroblastoma differentiation while inhibiting proliferation. Here, we demonstrate the synergistic effect of inhibiting Akt and ROCK in antineuroblastoma and present the design and discovery of a new Akt/ROCK inhibitor, <b>B12</b>. …”
  10. 1710

    Discovery of Novel Oxazepine Derivatives as Akt/ROCK Inhibitors for Growth Arrest and Differentiation Induction in Neuroblastoma Treatment by Jinxin Che (791250)

    Published 2023
    “…Evidence suggests that targeted inhibitors may provide opportunities for inducing neuroblastoma differentiation while inhibiting proliferation. Here, we demonstrate the synergistic effect of inhibiting Akt and ROCK in antineuroblastoma and present the design and discovery of a new Akt/ROCK inhibitor, <b>B12</b>. …”
  11. 1711
  12. 1712

    Exposure to 50 Hz electromagnetic field changes the efficiency of the scorpion alpha toxin by Milena Jankowska (5671298)

    Published 2018
    “…We observed a decrease of the toxin effect on the cercal nerve activity, but the toxic effect of LqhαIT on the connective nerve was increased. …”
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    Mechanistic Insight of Synthesized 1,4-Dihydropyridines as an Antidiabetic Sword against Reactive Oxygen Species by Peter A. Sidhom (14313061)

    Published 2022
    “…Also, compound <b>8b</b> decreased blood glucose by α-glucosidase inhibition (IC<sub>50</sub> = 4.48 ± 0.32 μM), compared to acarbose (7.40 ± 0.41 μM), based selectively on the plasma window of <b>8b</b>. …”
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  20. 1720

    Treatment with proteasome inhibitor bortezomib decreases organic anion transporting polypeptide (OATP) 1B3-mediated transport in a substrate-dependent manner by Khondoker Alam (1443499)

    Published 2017
    “…Pretreatment with bortezomib (50–250 nM, 2–7 h) significantly decreased transport of [<sup>3</sup>H]CCK-8, a specific OATP1B3 substrate, in HEK293-OATP1B3 and human sandwich-cultured hepatocytes (SCH). …”