Effect of FAAH inhibition on depressive-like behavior in WKY rats. by K. Yaragudri Vinod (323103)

“…<p>Treatment with URB597 (0.3 mg/kg, i.p. for 7 days) elicited a significant decrease in total time spent in immobility (50%, p<0.01; A) and a marked increase in sucrose intake (48%, p<0.05; B) without any effect on the spontaneous locomotor activity in the open field (C) in WKY rats compared to vehicle treated WKY rats.…”

Image1_Ethyl 2-Succinate-Anthraquinone Attenuates Inflammatory Response and Oxidative Stress via Regulating NLRP3 Signaling Pathway.TIF by Burong Feng (11661529)

“…In vivo, we revealed that the LHD, in different doses (6.25 mg/kg, 12.5 mg/kg, 25 mg/kg, 50 mg/kg), has a protective effect on stress physiological responses by assessing the body temperature of mice. …”

Image2_Ethyl 2-Succinate-Anthraquinone Attenuates Inflammatory Response and Oxidative Stress via Regulating NLRP3 Signaling Pathway.TIF by Burong Feng (11661529)

“…In vivo, we revealed that the LHD, in different doses (6.25 mg/kg, 12.5 mg/kg, 25 mg/kg, 50 mg/kg), has a protective effect on stress physiological responses by assessing the body temperature of mice. …”

c-MET Protects Breast Cancer Cells from Apoptosis Induced by Sodium Butyrate by Bo Sun (177052)

Schematic illustration of the variable-ranking process for the derivation cohort. by Johan Nilsson (364438)

Lack of off-target silencing of other keratins by lead inhibitor for K12 Leu132Pro mutation, siRNA K12-L132P-9. by Haihui Liao (192426)

Presentation_1_Mapping the Substrate-Binding Sites in the Phosphatidylserine Synthase in Candida albicans.pptx by Yue Zhou (71752)

Dietary Heme Alters Microbiota and Mucosa of Mouse Colon without Functional Changes in Host-Microbe Cross-Talk by Noortje IJssennagger (112298)

Data_Sheet_2_Identification of Trypanosoma cruzi Polyamine Transport Inhibitors by Computational Drug Repurposing.PDF by Chantal Reigada (3844975)

“…Three of them, promazine, chlorpromazine, and clomipramine, showed to be effective inhibitors of putrescine uptake, and also revealed a high trypanocidal activity against T. cruzi amastigotes (IC₅₀ values of 3.8, 1.9, and 2.9 μM, respectively) and trypomastigotes (IC₅₀ values of 3.4, 2.7, and 1.3 μM, respectively) while in epimastigotes the IC₅₀ were significantly higher (34.7, 41.4, and 39.7 μM, respectively). …”

Data_Sheet_1_Identification of Trypanosoma cruzi Polyamine Transport Inhibitors by Computational Drug Repurposing.PDF by Chantal Reigada (3844975)

“…Three of them, promazine, chlorpromazine, and clomipramine, showed to be effective inhibitors of putrescine uptake, and also revealed a high trypanocidal activity against T. cruzi amastigotes (IC₅₀ values of 3.8, 1.9, and 2.9 μM, respectively) and trypomastigotes (IC₅₀ values of 3.4, 2.7, and 1.3 μM, respectively) while in epimastigotes the IC₅₀ were significantly higher (34.7, 41.4, and 39.7 μM, respectively). …”

Effects of land use and microclimate changes on ant foraging in two Neotropical biomes by Icaro Wilker (17548428)

“…We sampled between 8 a.m. and 12 p.m., however, the transect had only 5 sampling points spaced 50 m apart. …”

Calculating Orthologs in Bacteria and Archaea: A Divide and Conquer Approach by Mihail R. Halachev (192584)

Soy isoflavones genistein and daidzein protect primary cortical cultures from Tat neurotoxicity. by Sheila M. Adams (322032)

“…<p>Primary cortical neurons were exposed to estrogen (0.1, 2.0 and 10 nM), or isoflavones (0.05, 0.2 and 1 µM) 24 hr prior to the start of Tat_1–86 B (50 nM) treatment. Cell viability was assessed by Live/Dead assay. …”

Rice (<i>Oryza sativa</i> L.) developmental stages. by Nathaniel B. Lyman (449148)

“…<p>This figure describes the developmental stages relevant to this study. <b>a,</b> Vegetative, reproductive and ripening growth stages are defined relative to the observed 50% heading and emergence dates at each station. …”

Lkb1-deficiency alters the expression of Notch signalling components and leads to the abnormal intestinal secretory cell differentiation. by Boris Y. Shorning (232815)

“…D, Delta ligand (Dll1) immunostaining at day 6 in induced <i>Cre</i>-negative Lkb1 <i>fl/fl</i> (+/+) and Lkb1-deficient (‘−/−’) intestines displaying a decrease in Dll1 expression in Paneth and goblet cells of Lkb1-deficient intestines. …”

Changes in expression of epithelial and mesenchymal proteins in primary human small airway epithelial cells (SAEC) and large airway epithelial cells (LAEC) stimulated with TGFβ1 <i... by Balarka Banerjee (107946)

“…(A) Initial immunoblots suggested a marked increase in mesenchymal markers and corresponding decrease in epithelial markers after 96 h of stimulation. …”

ReFus GS vs. PS files by Eric Butoto (11923394)

“…We observed similar cumulative responses to GS and PS, representing decreases of about 50% of mean FER and FUM compared to the base population. …”

Phenotypic analyses of tumour cells in co-culture experiments. by Victor Trevino (8900)

“…The presence of normal cells are seen to (A) increase the population doubling time (PDT), (B) decrease the total cell number, (C) have no significant effect on apoptosis, (D) decrease the number and (E) size of the cell clusters and (F) increase the number of single cells. …”

RPL37, RPS15, and RPS20 bind to and regulate MdmX levels. by Lilyn Daftuar (433919)

“…Endogenous proteins were detected by immunoblotting with the indicated antibodies. (g) Decrease in MdmX mRNA by RPL37. U2OS cells were seeded in 60 mM tissue culture plates and transfected with Myc-RP (0–5.0 µg). …”

<i>Transthyretin</i> Is a Key Regulator of Myoblast Differentiation by Eun Ju Lee (414663)

“…<div><p><i>Transthyretin</i> (<i>TTR</i>) is a known carrier protein for thyroxine (T₄) and retinol-binding protein in the blood that is primarily synthesized in the liver and choroid plexus of the brain. Herein, we report that the <i>TTR</i> gene is expressed in skeletal muscle tissue and up-regulated during myotube formation in C2C12 cells. …”