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point decrease » point increase (Expand Search)
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12 wt » 2 wt (Expand Search), 1 wt (Expand Search)
point decrease » point increase (Expand Search)
fold decrease » fold increase (Expand Search), fold increased (Expand Search)
wt decrease » we decrease (Expand Search), _ decrease (Expand Search), nn decrease (Expand Search)
a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
12 wt » 2 wt (Expand Search), 1 wt (Expand Search)
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Aquaporin 2 Mutations in <i>Trypanosoma brucei gambiense</i> Field Isolates Correlate with Decreased Susceptibility to Pentamidine and Melarsoprol
Published 2013“…Here we describe two different kinds of <i>TbAQP2</i> mutations found in <i>T. b. gambiense</i> field isolates: simple loss of <i>TbAQP2</i>, or loss of wild-type <i>TbAQP2</i> allele combined with the formation of a novel type of <i>TbAQP2/3</i> chimera. The identified mutant <i>T. b. gambiense</i> are 40- to 50-fold less sensitive to pentamidine and 3- to 5-times less sensitive to melarsoprol than the reference isolates. …”
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Eltrombopag markedly decreases levels of ROS in MOLM14 cells.
Published 2015“…B) Graphic presentation of ROS levels measured by flow cytometry in cells treated with E (5 μM) or DPI (25 μM), an inhibitor of NADPH oxidase known to decrease an intracellular level of ROS, or untreated (CTR) cells. …”
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Frictional Effects on RNA Folding: Speed Limit and Kramers Turnover
Published 2018“…In the high-friction regime (η ≳ 10<sup>–5</sup> Pa·s), for both HP and PK, <i>k</i><sub>F</sub> values decrease as 1/η, whereas in the low friction regime, <i>k</i><sub>F</sub> values increase as η increases, leading to a maximum folding rate at a moderate viscosity (∼10<sup>–6</sup> Pa·s), which is the Kramers turnover. …”
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The numbers of mature T cells from transgenic mice bearing mutated CD3ε were decreased, and they were actively proliferating in a homeostatic manner.
Published 2009“…Fold decreases for the two populations are indicated. …”
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GCase activity is significantly decreased in the brain and liver of the homozygous <i>GBA1</i> D409V KI mouse model at 4, 8, and 12 months of age.
Published 2021“…In whole brain homogenate (A,C) and liver homogenate (B,D), GCase activity is significantly decreased in the <i>GBA1</i> D409V KI homozygous (HOM) mice as compared to C57Bl/6 wild type (WT) mice (n = 7/group). …”
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TRIM5 restriction of HIV-1 has decreased during evolution leading to humans.
Published 2013“…Original data is found in <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.1000301#pbio.1000301-Goldschmidt1" target="_blank">[30]</a> and shows that the antiviral gene TRIM5 restricted HIV-1 better at points in evolution earlier than the chimp–human common ancestor than it does after that. …”