Search alternatives:
wt decrease » we decrease (Expand Search), _ decrease (Expand Search), awd decreased (Expand Search)
nn decrease » _ decrease (Expand Search), gy decreased (Expand Search), b1 decreased (Expand Search)
a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
12 wt » 2 wt (Expand Search), 1 wt (Expand Search)
wt decrease » we decrease (Expand Search), _ decrease (Expand Search), awd decreased (Expand Search)
nn decrease » _ decrease (Expand Search), gy decreased (Expand Search), b1 decreased (Expand Search)
a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
12 wt » 2 wt (Expand Search), 1 wt (Expand Search)
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1821
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1822
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1823
OSU-HDAC-44 decreased RhoA activity via srGAP1 induction, leading to F-actin dysregulation.
Published 2010“…<p>(<b>A</b>) Chromatin-immunoprecipitation-PCR analyses confirmed that treatment with 2.5 µM OSU-HDAC-44 for 2 h induced acetylation of histone H3 (H3K9K14Ac) in the promoter region of <i>srGAP1</i>, <i>NR4A1</i> and <i>FOXO4</i> genes. …”
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1824
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1827
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1832
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1834
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1835
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1836
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1838
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1839
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1840
Bortezomib in combination with the PLK1 inhibitor BI 2536 induces a significant downregulation of the total levels and phosphorylation of Bcr-Abl, a decrease of downstream phosphorylated STAT5 and a caspase-dependent cell death in TKIs-resistant and –sensitive K562 cell lines.
Published 2013“…K562 and K562-R cells were treated with 9nM bortezomib and 8nM BI 2536 for 60h, followed by the detection of Bcr-Abl and phosphorylated STAT5. The combined treatment resulted in a marked decrease of the total levels of Bcr-Abl, which correlates with a decrease in the phosphorylation of the downstream STAT5 protein, in both K562 and K562-R cells. β-Actin was used as an internal loading control. …”