Showing 1,821 - 1,840 results of 102,257 for search '(( 12 wt decrease ) OR ( 5 ((((mean decrease) OR (nn decrease))) OR (a decrease)) ))', query time: 1.33s Refine Results
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    OSU-HDAC-44 decreased RhoA activity via srGAP1 induction, leading to F-actin dysregulation. by Yen-An Tang (187547)

    Published 2010
    “…<p>(<b>A</b>) Chromatin-immunoprecipitation-PCR analyses confirmed that treatment with 2.5 µM OSU-HDAC-44 for 2 h induced acetylation of histone H3 (H3K9K14Ac) in the promoter region of <i>srGAP1</i>, <i>NR4A1</i> and <i>FOXO4</i> genes. …”
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    Bortezomib in combination with the PLK1 inhibitor BI 2536 induces a significant downregulation of the total levels and phosphorylation of Bcr-Abl, a decrease of downstream phosphorylated STAT5 and a caspase-dependent cell death in TKIs-resistant and –sensitive K562 cell lines. by Octavian Bucur (470431)

    Published 2013
    “…K562 and K562-R cells were treated with 9nM bortezomib and 8nM BI 2536 for 60h, followed by the detection of Bcr-Abl and phosphorylated STAT5. The combined treatment resulted in a marked decrease of the total levels of Bcr-Abl, which correlates with a decrease in the phosphorylation of the downstream STAT5 protein, in both K562 and K562-R cells. β-Actin was used as an internal loading control. …”