Image6_Arbuscular mycorrhizal fungi alleviate Mn phytotoxicity by altering Mn subcellular distribution and chemical forms in Lespedeza davidii.tif by Gao Pan (12510447)

“…</p>Methods<p>In this study, Lespedeza davidii inoculated with or without AMF (Glomus mosseae) under different Mn concentrations (0 mmol/L, 1 mmol/L, 5 mmol/L, 10 mmol/L, and 20 mmol/L) was cultivated via a pot experiment, and plant biomass, physiological and biochemical characteristics, manganese absorption, subcellular distribution, and chemical forms of Mn were examined.…”

Image 1_Efficacy and safety of leuprorelin (Boennuokang®) plus endocrine therapy in premenopausal women with HR+/HER2− breast cancer.tif by Xiuping Wu (527012)

“…During 24 months, the follicle-stimulating hormone level was decreased from 7.7 to 4.8 mIU/mL, and the luteinizing hormone level was decreased from 7.9 to 0.2 mIU/mL (both P < 0.001). …”

Image 2_Efficacy and safety of leuprorelin (Boennuokang®) plus endocrine therapy in premenopausal women with HR+/HER2− breast cancer.tif by Xiuping Wu (527012)

“…During 24 months, the follicle-stimulating hormone level was decreased from 7.7 to 4.8 mIU/mL, and the luteinizing hormone level was decreased from 7.9 to 0.2 mIU/mL (both P < 0.001). …”

Relationship of body mass index and waist circumference with clinical outcomes following percutaneous coronary intervention by Yonggu Lee (436856)

“…Patients were evenly divided into 4 groups according to BMI (Q1_BMI, Q2_BMI, Q3_BMI and Q4_BMI) and WC (Q1_WC, Q2_WC, Q3_WC and Q4_WC).</p><p>Results</p><p>A total of 1,421 patients were observed for 5 years. …”

CEP164 regulates cell cycle progression and proliferation. by Gisela G. Slaats (648603)

“…<p>(A) RPE-FUCCI cells and their daughter cells were tracked by live cell imaging for 72 hours (hr) after transfection. …”

Key barriers and enablers associated with uptake and continuation of oral pre-exposure prophylaxis (PrEP) in the public sector in Zimbabwe: Qualitative perspectives of general popu... by Makaita M. Gombe (8294007)

“…Clients who opted for PrEP preferred it to other forms of HIV prevention. SDCs reported decreased condom use after PrEP initiation and in some cases were using PrEP while trying to conceive a child. …”

Antimicrobial activity of RP-1 peptide conjugate with ferrocene group by Natalia C. S. Costa (8626206)

“…In comparison with amphotericin B, a second-line drug approved for leishmaniasis treatment, (IC₅₀ = 0.63 μmol L^-1), Fc-RP1 was more active and showed a 2.5-fold higher selectivity index. …”

Simulated currents of the voltage-gated potassium channels SHL-1, KVS-1, SHK-1, IRK-1/3, KQT-3, EGL-36 and EGL-2. by Martina Nicoletti (6900464)

“…The current inactivates exponentially with a time constant that is a decreasing function of voltage ( at 0 mV, <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0218738#pone.0218738.s003" target="_blank">S1 Fig</a>). …”

Functional Characterization of FLT3 Receptor Signaling Deregulation in Acute Myeloid Leukemia by Single Cell Network Profiling (SCNP) by David B. Rosen (104278)

“…Specifically, increased basal p-Stat5 levels, decreased FLT3L induced activation of the PI3K and Ras/Raf/Erk pathways, decreased IL-27 induced activation of the Jak/Stat pathway, and heightened apoptotic responses to agents inducing DNA damage were observed in FLT3-ITD AML samples. …”

Kmo inhibition or depletion impairs lysosome acidification in both exposed and infected macrophages. by Emily R. Goering (22486572)

“…<p>(<b>A</b>) Kmo inhibition with Ro61–8048 decreased maximum Lysotracker fluorescence in both infected and exposed bystander macrophages, which was restored upon treatment with exogenous 3-HK. …”

Table_1_Effects of Immobilized Antimicrobial Peptides on Growth Performance, Serum Biochemical Index, Inflammatory Factors, Intestinal Morphology, and Microbial Community in Weanin... by Nian Liu (29935)

“…The results showed the following: (1) compared with the CON group, the average daily gain in the whole experimental time (p < 0.05) was significantly increased, and the diarrhea rate of weaning piglets was decreased (p < 0.01) in the IAMPs group; (2) compared with the CON group, the concentrations of serum IgM and superoxide dismutase (SOD) in the IAMPs group were significantly higher than the CON and AB groups (p < 0.01); (3) compared with CON group, the concentrations of serum interleukin (IL)-10 and transforming growth factor (TGF-β) were significantly increased (p < 0.05), and the concentration of IL-12 was significantly decreased (p < 0.05) in the IAMPs group; (4) compared with CON group, the concentrations of serum endotoxin and D-lactate of piglets were significantly reduced (p < 0.05), and the relative expression of ZO-1 and occludin in the jejunum of piglets were significantly increased (p < 0.05) in the IAMPs group; (5) compared with the CON group, the villus height of the duodenum and jejunum of weaning piglets in IAMPs and AB groups was significantly increased (p < 0.05); and (6) compared with CON group, the relative abundance of Escherichia–Shigella in the colon and cecal digesta was decreased. …”

Regulation of amino acid and nucleotide metabolism by crustacean hyperglycemic hormone in the muscle and hepatopancreas of the crayfish <i>Procambarus clarkia</i> by Wenfeng Li (431916)

“…Finally, in the muscle, levels of several amino acids decreased significantly, while those of 5 other amino acids or related compounds significantly increased in response to CHH gene silencing. …”

Data_Sheet_1_Central and Obstructive Apneas in Heart Failure With Reduced, Mid-Range and Preserved Ejection Fraction.docx by Chiara Borrelli (6520607)

“…When stratified according to left ventricular EF, CA prevalence decreased (daytime: 57 vs. 43 vs. 42%, p = 0.001; nighttime: 66 vs. 48 vs. 34%, p < 0.0001) from HFrEF to HFmrEF and HFpEF, while OA prevalence increased (daytime: 5 vs. 8 vs. 18%, p < 0.0001; nighttime 20 vs. 29 vs. 53%, p < 0.0001).…”

Data_Sheet_1_Stress Response Simulated by Continuous Injection of ACTH Attenuates Lipopolysaccharide-Induced Inflammation in Porcine Adrenal Gland.PDF by Zhiyuan Sun (1668358)

“…Thirty-days-old Duroc × Landrace × Large White crossbred piglets (12 ± 0.5 kg) were randomly allocated into four groups in a 2 × 2 factorial arrangement of treatments, including ACTH pretreatment (with or without ACTH injection) and LPS challenge (with or without LPS injection). …”

Cycles in RNA level fluctuations. by Zhongneng Xu (11177972)

“…(B) RNA level fluctuations with a cycle length of 5 RNA ages. TR and TRA curves overlap (DRA is set to 50. …”

Evidence for changed homeostasis of T_regs in children with high malaria exposure. by Michelle J. Boyle (204737)

“…Data from YoPro staining is representative of all measures of apoptosis (see <a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1005041#ppat.1005041.s006" target="_blank">S5 Fig</a> additional measures of apoptosis including activated Caspase 3 and AnnexinV). …”

Table1_The importance of ultrasound examination in care of juvenile idiopathic arthritis patients: 9 months follow-up study.pdf by Ausra Snipaitiene (16712643)

“…Introduction<p>Juvenile idiopathic arthritis (JIA) is a group of rare musculoskeletal disorders with chronic inflammation of joints, typically manifesting before the age of 16 years. …”

TSC repression in EBs is sufficient for ISC differentiation. by Subir Kapuria (121321)

“…The fraction of polyploid cells (defined as any cell with a nucleus that is larger than the smallest Dl+ cell) in ISC clones decreases dramatically in N loss of function conditions, and is rescued when <i>Tsc1</i> is also lost. …”

Overview of known molecular pathways of ATRX. by Edward Wang (735287)

“…This recruitment is facilitated by HP1α, which recognizes H3K9me3 marks, allowing ATRX/DAXX to deposit histone H3.3 and maintain heterochromatin integrity [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0313380#pone.0313380.ref001" target="_blank">1</a>,<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0313380#pone.0313380.ref002" target="_blank">2</a>,<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0313380#pone.0313380.ref004" target="_blank">4</a>,<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0313380#pone.0313380.ref005" target="_blank">5</a>,<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0313380#pone.0313380.ref006" target="_blank">6</a>]. …”

Prospective, multicenter French study evaluating the clinical impact of the Breast Cancer Intrinsic Subtype-Prosigna^® Test in the management of early-stage breast cancer... by Delphine Hequet (4521211)

“…Intrinsic tumor subtypes as assessed by the Prosigna test were 114 (58.2%) Luminal A, 79 (40.3%) Luminal B, 1 (0.5%) HER-2 enriched (HER-2E), and 2 (1.0%) basal-like. …”