Image_2_SIRT1 haplo-insufficiency results in reduced cortical bone thickness, increased porosity and decreased estrogen receptor alpha in bone in adult 129/Sv female mice.tif by Hanna Artsi (777390)

“…</p>Methods<p>To investigate the mechanisms of gender differences in SIRT1 skeletal effect, we investigated femoral and vertebral cortical and cancellous bone in global Sirt1 haplo-insufficient 129/Sv mice aged 2,7,12 months lacking Sirt1 exons 5,6,7 (Sirt1^+/Δ) and their wild type (WT) counterparts.…”

Image_1_SIRT1 haplo-insufficiency results in reduced cortical bone thickness, increased porosity and decreased estrogen receptor alpha in bone in adult 129/Sv female mice.tif by Hanna Artsi (777390)

“…</p>Methods<p>To investigate the mechanisms of gender differences in SIRT1 skeletal effect, we investigated femoral and vertebral cortical and cancellous bone in global Sirt1 haplo-insufficient 129/Sv mice aged 2,7,12 months lacking Sirt1 exons 5,6,7 (Sirt1^+/Δ) and their wild type (WT) counterparts.…”

ATG 5 down-regulation decreases human A53T ASYN-induced death in rat cortical neurons. by Maria Xilouri (264240)

Disruption of bacterial K⁺ homeostasis decreases Mtb colonization of macrophages. by Nathan J. MacGilvary (6294314)

“…Each point on the graph represents a bacterium or a tight cluster of bacteria (black circles—WT, red squares– Δ<i>ceoBC</i>, blue triangles—<i>ceoBC</i>*). p-values were obtained with a Mann-Whitney statistical test. …”

EphA4 immunostaining is decreased adjacent to injury site in ephrin-A5-Fc treated mice. by Yona Goldshmit (205708)

“…<p>Immunohistochemical analysis of (A,B) GFAP, (C–F) EphA4 and (G,H) CSPG expression at 2 weeks after spinal cord hemisection and 2 weeks of ephrin-A5-Fc treatment indicated that there was robust GFAP staining in both treated and control mice (A,B). …”

Increased fat accumulation is not the result of increased food consumption or decreased physical activity. by Jessica N. Saykally (368303)

RNAP II CTD phosphoserine-2 levels decreased with increasing amounts of DRB. by Mark Ou (474248)

Decreased Ca⁺⁺ Induces Rapid Release of Tir from EPEC by Alyson I Swimm (84612)

The VPS C846G mutation decreases the stability of VPS11 protein. by Jinglan Zhang (401545)

Tim-3 deficiency enhances the levels of proinflammatory cytokines and decreases the parasite burden. by Houbao Qi (11996039)

Knockout of CD146 in the nervous system resulted in decreased locomotor activity in mice. by Tao Tu (456663)

The cytotoxic ability of virus-specific CD8 T cells was decreased in the absence of RANTES. by Alison Crawford (212922)

Expression of MHC I is decreased by P2X7R activation. by Alberto Baroja-Mazo (441935)

Decreased primary seed dormancy and vivipary phenotype of <i>abi4</i>. by Kai Shu (424728)

BCG-AS−Ndk has decreased intracellular survival due to increased phagolysosome fusion. by Jim Sun (367834)

Decreased bacterial burden in mice with T-cell targeted deletion of HIF-1 α. by Manfred Thiel (310810)

Mutation of stathmin phosphorylation sites decreases sensitivity to bortezomib and influences tubulin polymerization. by Feng Ge (64593)

Decrease of junctional zone area in low protein placentas at E10.5, E17.5 and E18.5. by Paula N. Gonzalez (372538)

GFRα2 expression was dramatically decreased in Runx1 knockout mice. by Ting Wang (16292)

“…<p>ISH for GFRα2 in WT (<b><i>A</i></b>) and Runx1 knock out (<b><i>A^/</i></b>) mouse DRG showed significant reduction of GFRα2 in Runx1^−/− ganglia. …”

Mst1^−/− mice exhibit decreased incidence and severity of CIA. by Konstantin V. Salojin (567844)