Pharmacological signatures of the reduced incidence and the progression of cognitive decline in ageing populations suggest the protective role of beneficial polypharmacy by Anatoly L. Mayburd (7827782)

“…Confounder analysis confirmed an independent effect of protective complexity in multivariate context. A sub-cohort with lifelong odds of dementia decreased > 5-folds was identified; this sub-cohort should be studied in further details, including controlled clinical trials. …”

Proof-of-concept simulations for VHP-based polypeptide system. by Marie Weiel (6499430)

“…<p>Results are shown for parameters (<i>T</i>, <i>k</i>_<i>χ</i>) = (90, 5 ⋅ 10⁻⁸ <i>ε</i>). (A) End-to-end C_α distance distributions. …”

Coupling Mechanism of Electromagnetic Field and Thermal Stress on <i>Drosophila melanogaster</i> by Zi-Yan Zhang (3112146)

“…Therefore, thermal stress and ELF-EMF elicited a synergistic effect.</p></div>…”

Neuroprotective Effects of Ginsenoside Rb1 on High Glucose-Induced Neurotoxicity in Primary Cultured Rat Hippocampal Neurons by Di Liu (30843)

“…The results from MTT, TUNEL labeling and Annexin V-FITC/PI/Hoechst assays showed that incubating neurons with 50 mM high glucose for 72h decreased cell viability and increased the number of apoptotic cells whereas treating neurons with 1 μM Rb1 for 72h protected the neurons against high glucose-induced cell damage. …”

Propofol attenuates sepsis-induced acute kidney injury by regulating miR-290-5p/CCL-2 signaling pathway by Guodong Zheng (714597)

“…Mice were treated with propofol (50 mg/kg) twice within 24 h. Survival outcome was monitored within 48 h. …”

Raw data. by Louise Nicole Hanson (19267635)

“…<div><p>Previous research on body appreciation across the lifespan has produced conflicting results that it increases with age, decreases with age, or is generally stable with an increase in women over 50-years-old. …”

Dynamic changes of plasma extracellular vesicle long RNAs during perioperative period of colorectal cancer by Qing Hua (1795123)

“…Compared with T0, there were 110 differentially expressed genes (DEGs) in T1, 60 DEGs in T2, and 50 DEGs in T3. A total of 11 DEGs were found at all three time points and were related to membrane potential. …”

Air-Adapted <i>Methanosarcina acetivorans</i> Shows High Methane Production and Develops Resistance against Oxygen Stress by Ricardo Jasso-Chávez (120236)

“…<div><p><i>Methanosarcina acetivorans</i>, considered a strict anaerobic archaeon, was cultured in the presence of 0.4–1% O₂ (atmospheric) for at least 6 months to generate air-adapted cells; further, the biochemical mechanisms developed to deal with O₂ were characterized. …”

Image_1_Xiaochaihutang Inhibits the Activation of Hepatic Stellate Cell Line T6 Through the Nrf2 Pathway.TIF by Rui Hu (505795)

“…Rats in treatment groups were given the appropriate doses of XCHT granules (5 g/kg) and Silybin (50 mg/kg) for 6 days, and the serum were obtained. …”

The malleable gut microbiome of juvenile rainbow trout (<i>Oncorhynchus mykiss</i>): Diet-dependent shifts of bacterial community structures by Stéphanie Céline Michl (4023134)

“…The overall alpha diversity significantly decreased with increasing plant protein inclusion levels and with age of experimental animals. …”

SNEV inhibits spliceosome formation, but does not disrupt already formed complexes by Johannes Grillari (13055)

“…Immunodepletion of SNEV only slightly decreases formation of the spliceosome, while after addition of recombinant SNEV no splicing complexes can be detected. () Already formed complexes are not disrupted by addition of SNEV in a time course experiment. …”

Dau-induced cardiotoxicity in vivo. by Yasuhiro Ichikawa (324219)

“…<p>(A) Ejection fraction (EF) was decreased with 9w Dau treatment. …”

DataSheet_1_Proteomic and metabolomic analysis on cadmium-induced mitochondrial toxicity in liver tissues of juvenile olive flounder Paralichthys olivaceus.pdf by Zhen Lu (266590)

“…</p>Results<p>After water-bonre exposure for 14 days, two Cd treatments decreased MMPs significantly and caused ultrastructural-damaged mitochondria in flounder livers. …”

Theory of Borazine-Derived Nanothreads: Enumeration, Reaction Pathways, and Piezoelectricity by Tao Wang (12008)

“…Borazine is isoelectronic to benzene yet with substantial bond polarity, thus motivating a theoretical examination of borazine-derived nanothreads with degrees of saturation of 2, 4, and 6 (defined as the number of four-coordinated boron and nitrogen atoms per borazine formula unit). …”

EMMPRIN Promotes Angiogenesis, Proliferation, Invasion and Resistance to Sunitinib in Renal Cell Carcinoma, and Its Level Predicts Patient Outcome by Mototaka Sato (461331)

“…</p> <p>Experimental Design</p><p>EMMPRIN expression was examined in 50 RCC patients treated with radical nephrectomy. …”

Different Growth and Physiological Responses to Cadmium of the Three <i>Miscanthus</i> Species by Haipeng Guo (582824)

“…To determine any differences in resistance of <i>Miscanthus</i> to Cd, we examined plant growth, net photosynthetic rate (Pn), activities of anti-oxidant and C₄ photosynthetic enzymes, concentrations of Cd in leaves and roots, and observed the chloroplast structure in three <i>Miscanthus</i> species treated with 0, 10, 50, 100 or 200 μM Cd in solutions. <i>Miscanthus sinensis</i> showed more sensitivity to Cd, including sharp decreases in growth, Pn, PEPC activity and damage to chloroplast structure, and the highest H₂O₂ and Cd concentrations in leaves and roots after Cd treatments. …”

Image_4_Vaginal Microbiota and Cytokine Levels Predict Preterm Delivery in Asian Women.tiff by Manoj Kumar (205700)

“…Using 16S ribosomal RNA gene sequencing we identified a predictive vaginal microbiota signature for PTB that was detectable as early as the first trimester of pregnancy, characterized by higher levels of Prevotella buccalis, and lower levels of Lactobacillus crispatus and Finegoldia, accompanied by decreased levels of cytokines including IFNγ, IL-4, and TNFα. …”

DataSheet1_Design parameters affecting mechanical failure and electrochemical degradation of ultrathin Li-ion pouch cells under repeated flexing.pdf by Kyungbae Kim (2158606)

“…It was observed that the discharge capacity for all cell types studied herein was only slightly decreased (∼6–7% at 2C-rate) even after 3,000 repeated bends at a 25 mm radius of curvature provided if the bending axis is aligned to the long dimension of the cell. …”

Image_1_Vaginal Microbiota and Cytokine Levels Predict Preterm Delivery in Asian Women.tiff by Manoj Kumar (205700)

“…Using 16S ribosomal RNA gene sequencing we identified a predictive vaginal microbiota signature for PTB that was detectable as early as the first trimester of pregnancy, characterized by higher levels of Prevotella buccalis, and lower levels of Lactobacillus crispatus and Finegoldia, accompanied by decreased levels of cytokines including IFNγ, IL-4, and TNFα. …”

Abnormal spermatogenesis in <i>Dicer1</i> knockout mice. by Hanna M. Korhonen (205372)

“…<p>A) Decreased size of adult <i>Dcr(fx/fx);Ngn3Cre</i> testes as compared to <i>Dcr(fx/fx)</i> or <i>Dcr(fx/wt); Ngn3Cre</i> testes. …”