H3K27me3 levels show differences across SMN differentiation in <i>Suz12GT</i> cells compared to wt cells. by Seraphim R. Thornton (647875)

“…Expression for each of the five genes is shown, log₂ transformed, for wild-type (wt) (top), <i>Suz12^GT</i> (2^nd), <i>Suz12^Δ</i> (3^rd), and <i>Eed^null</i> (bottom) cells. …”

Absence of adaptive immunity decreases tumor cell damage in MDR1A deficiency. by Eva Maria Hennenberg (4234018)

Decreased production of highly reactive oxygen species production induced by complement-mediated phagocytosis in Rab27a-knockdown cells. by Tatsumi Kawakami (505540)

P2Y12 deficiency decreases lung metastasis but has no effect on primary tumor growth in the LLC (Lewis lung carcinoma) spontaneous pulmonary metastasis model. by Yanhua Wang (127897)

BT9 exhibits a dose- and time-dependent cytotoxic effect on medulloblastoma. by Zahra Motahari (6814013)

The inhibitory activity of the most active compounds against Glo-I enzyme with less than 50 µM. Their supportive corresponding docking values on two different protocols are display... by MohammedBashar Al-Qazzan (22439236)

Elemental analysis shows a decreased N content in N stressed cells without a change in their C content. by Steve Dagenais Bellefeuille (654383)

Podocyte specific KO of FcRn results in a significant decrease in albuminuria, glomerulosclerosis, and glomerular crescents after nephrotoxic serum nephritis induction. by James F. Dylewski (9922380)

Habitual Functional Electrical Stimulation Therapy Improves Gait Kinematics and Walking Performance, but Not Patient-Reported Functional Outcomes, of People with Multiple Sclerosis... by Marietta L. van der Linden (617342)

“…Compared to unassisted walking, FES resulted in statistically significant improvements in peak dorsiflexion in swing (p = 0.006), 10MWT (p = 0.006) and 2 minWT (p = 0.002). Effect sizes for the training effect, defined as the change from unassisted walking at baseline to that at 12 weeks, indicated improved ankle angle at initial contact (2.6°, 95% CI −1° to 4°, d = 0.78), and a decrease in perceived exertion over the 2 min walking tests (−1.2 points, 95% CI −5.7 to 3.4, d = −0.86). …”

Podocyte specific KO of FcRn results in a significant decrease in glomerular crescents 8 days after anti-GBM disease induction. by James F. Dylewski (9922380)

High-throughput drug screen reveals HDAC and proteasome inhibitors as potent drug classes against synovial sarcoma. by Aimée N. Laporte (3617987)

“…(C) Compounds that brought about greater than 90% decreased relative cell viability were scored as 1 (+++), 75.1–90% as 0.5 (++), 50–75% as 0.25 (+) and less than 50% as 0 (-). …”

Spontaneous physical activity and respiratory quotient (RQ) in WT and NMIIC KO mice. by Hiroki Hamaguchi (22783780)

SAA in a 50 year-old woman with HHT and severe liver involvement. by Jacques Sellier (8351355)

The total muscle and motor unit capacities for initial target forces of 15, 50 and 85% until total muscle capacity decreased to 15% MVC (ie. 85% muscle fatigue for each trial). by Jim R. Potvin (4062412)

LC–MS/MS analysis for EETs (8, 9–, 11, 12–, and 14, 15–) and DHETs (8, 9–, 11, 12–, and 14, 15–) levels in WT and Tie2-sEH Tr mouse heart perfusates at baseline and post-ischemia.... by Ahmad Hanif (3094800)

“…Also, the levels of EETs were not affected in response to ischemia in either mouse strain (<i>P</i> > 0.05). 8,9-DHET (D), and 14,15-DHET (F) were decreased in Tie2-sEH Tr compared to WT mice (<i>P</i> < 0.05), whereas 11,12-DHET (E) was not significantly different between the two groups (<i>P</i> > 0.05). …”

Decreases in muscle size, muscle force, and TB mass in 3-mo Lmna^HSA-cko mice. by Lei Xiong (334812)

PCR-based confirmation of gene deletions in the 12xbb mutant, and of <i>pg1</i> and <i>pg2</i> in the 12xpg mutant. by Thomas Leisen (9248883)

Lysine 50 of Tat regulates expression of C5, CRLF2, APBA1, and BDNF genes. by Loreto Carvallo (4167607)

“…<p>THP-1Tat-Flag and THP-1Tat K50ATat-Flag cell lines (generated from independent experiments described in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0179882#pone.0179882.g005" target="_blank">Fig 5</a>) were differentiated to macrophages with PMA for 24 and 48 hours. …”

Activation of NMDA receptors with D-serine obviously limited the decrease of p-CREB in the hippocampus of the surviving LPS-treated mice. by Shuibing Zhang (4336402)

Nicotine decreased Akt phosphorylation in SK-BR-3 cells. by Masanori A. Murayama (5774585)