Collateral effects are pervasive and vary across parallel evolution experiments in <i>E</i>. <i>faecalis</i>. by Jeff Maltas (1598305)

“…Although the color scale ranges from a 4× decrease to a 4× increase in IC₅₀, it should be noted that both resistance to the selecting drug (diagonal blocks) and collateral effects can be significantly higher. …”

The airway intrinsic BX-C code determines the outcome of <i>hh</i> signaling. by Ryo Matsuda (685668)

“…Note that Salm expression in DT shows a posterior-to-anterior decrease. Upon overexpression of <i>Ubx</i> (G), <i>abdA</i> (H) or <i>AbdB</i> (I), DTa1 becomes negative for Kni and positive for Salm (asterisks). …”

Luciferase assay results of <i>KATNA1</i> and <i>SPG4</i>. by Dolunay Kelle (6388055)

“…Even though Elk1-3R decreased the activity more than wt-Elk1, the difference was not significant. …”

Gene trap insertion sites and effects on <i>Klf3</i> mRNA and protein. by Lois Kelsey (433080)

“…(B) <i>Klf3</i> mRNA in E12.5 whole embryos from the XS (grey squares) and CH (black circles) gene trap lines measured by qRT-PCR was significantly decreased in homozygotes (homo) but not heterozygotes (het). …”

Data_Sheet_4_Omeprazole Increases the Efficacy of Acyclovir Against Herpes Simplex Virus Type 1 and 2.PDF by Martin Michaelis (23843)

“…Omeprazole 80 μg/mL caused a 10.8-fold (Vero cells) and 47.7-fold (HaCaT cells) decrease of the acyclovir concentrations that reduced HSV-1-induced CPE formation by 50% (IC₅₀). …”

Data_Sheet_1_Unequal Impact of COVID-19 on Private and Academic Neurosurgical Workforce: Results of an International Survey.PDF by Sami Ridwan (11510080)

“…</p><p>Conclusion: The lockdown imposed in many countries by the COVID-19 outbreak called for immediate modification of working routine and resulted in a dramatic decrease of elective surgical procedures. …”

Data_Sheet_2_Omeprazole Increases the Efficacy of Acyclovir Against Herpes Simplex Virus Type 1 and 2.PDF by Martin Michaelis (23843)

“…Omeprazole 80 μg/mL caused a 10.8-fold (Vero cells) and 47.7-fold (HaCaT cells) decrease of the acyclovir concentrations that reduced HSV-1-induced CPE formation by 50% (IC₅₀). …”

Data_Sheet_1_Omeprazole Increases the Efficacy of Acyclovir Against Herpes Simplex Virus Type 1 and 2.PDF by Martin Michaelis (23843)

“…Omeprazole 80 μg/mL caused a 10.8-fold (Vero cells) and 47.7-fold (HaCaT cells) decrease of the acyclovir concentrations that reduced HSV-1-induced CPE formation by 50% (IC₅₀). …”

4-Phenyl-1,3-thiazole-2-amines as scaffolds for new antileishmanial agents by Carina Agostinho Rodrigues (5887349)

“…A target fishing study suggested that S-methyl-5-thioadenosine phosphorylase is a potential target to these compounds, which could be explored to enhance activity and decrease the potential toxic side effects. …”

Climatic factors driving vegetation declines in the 2005 and 2010 Amazon droughts by Wenqian Zhao (3937202)

“…The results showed that (i) in the Amazon vegetation greenness responded to precipitation, radiation and temperature, with apparent time lags for most averaging interval periods associated with vegetation index responses of 0–4, 0–9 and 0–6 months, respectively; (ii) on average, the three climatic factors without time lags explained 27.28±21.73% (mean±1 SD) of vegetation index variation in the Amazon basin, and this value increased by 12.22% and reached 39.50±27.85% when time lags were considered; (iii) vegetation greenness in this region in non-drought years was primarily affected by precipitation and shortwave radiation, and these two factors altogether accounted for 93.47% of the total explanation; and (iv) in the common epicenter of the two droughts, pixels with a significant variation in precipitation, radiation and temperature accounted for 36.68%, 40.07% and 10.40%, respectively, of all pixels showing a significant decrease in vegetation index in 2005, and 15.69%, 2.01% and 45.25% in 2010, respectively. …”

Table_1_In vitro investigation of the antiviral activity of propolis and chitosan nanoparticles against the genotype VII Newcastle disease virus.DOCX by Noura Alkhalefa (13387473)

“…The median tissue culture infectious dose (TCID50) assay demonstrated that the nanoparticles have antiviral effects after NDV exposure resulting in significant decrease in viral titer (TCID50) by 2, 2.66, and 2.5 log10 at 62 μg/ml of chitosan, 13 μg/ml of propolis, and 30 μg/ml of the propolis–chitosan mixture, respectively, compared with the control TCID50 value of 4 log10. …”

Data_Sheet_5_Omeprazole Increases the Efficacy of Acyclovir Against Herpes Simplex Virus Type 1 and 2.PDF by Martin Michaelis (23843)

“…Omeprazole 80 μg/mL caused a 10.8-fold (Vero cells) and 47.7-fold (HaCaT cells) decrease of the acyclovir concentrations that reduced HSV-1-induced CPE formation by 50% (IC₅₀). …”

Table_1_In vitro investigation of the antiviral activity of propolis and chitosan nanoparticles against the genotype VII Newcastle disease virus.DOCX by Noura Alkhalefa (13387473)

“…The median tissue culture infectious dose (TCID50) assay demonstrated that the nanoparticles have antiviral effects after NDV exposure resulting in significant decrease in viral titer (TCID50) by 2, 2.66, and 2.5 log10 at 62 μg/ml of chitosan, 13 μg/ml of propolis, and 30 μg/ml of the propolis–chitosan mixture, respectively, compared with the control TCID50 value of 4 log10. …”

Data_Sheet_3_Omeprazole Increases the Efficacy of Acyclovir Against Herpes Simplex Virus Type 1 and 2.PDF by Martin Michaelis (23843)

“…Omeprazole 80 μg/mL caused a 10.8-fold (Vero cells) and 47.7-fold (HaCaT cells) decrease of the acyclovir concentrations that reduced HSV-1-induced CPE formation by 50% (IC₅₀). …”

Force–displacement curves of M5. by Yukun Hu (427264)

“…The simulation results indicate that: i) the shear failure and flexural failure were the main failure modes of masonry walls; ii) shear failure could be viewed as the main failure mode of the model when the aspect ratio was less than 1.00; however, the flexural failure was considered to be the main failure mode of the model once the aspect ratio was greater than 1.00; iii) when a vertical load of 0.20 MPa was applied to the model, only flexural failure was observed, regardless of whether the aspect ratio of the model increased or decreased; the flexural shear mixed failure was captured within the range of 0.30 MPa– 0.50 MPa; the shear failure was the main failure mode within the range of 0.60 MPa– 0.70 MPa; and iv) the wall with an aspect ratio less than 1.00 could bear a higher horizontal load, and the increase in vertical load can significantly improve the horizontal load of the wall. …”

Design parameters of the model. by Yukun Hu (427264)

“…The simulation results indicate that: i) the shear failure and flexural failure were the main failure modes of masonry walls; ii) shear failure could be viewed as the main failure mode of the model when the aspect ratio was less than 1.00; however, the flexural failure was considered to be the main failure mode of the model once the aspect ratio was greater than 1.00; iii) when a vertical load of 0.20 MPa was applied to the model, only flexural failure was observed, regardless of whether the aspect ratio of the model increased or decreased; the flexural shear mixed failure was captured within the range of 0.30 MPa– 0.50 MPa; the shear failure was the main failure mode within the range of 0.60 MPa– 0.70 MPa; and iv) the wall with an aspect ratio less than 1.00 could bear a higher horizontal load, and the increase in vertical load can significantly improve the horizontal load of the wall. …”

Force–displacement curves of M3. by Yukun Hu (427264)

“…The simulation results indicate that: i) the shear failure and flexural failure were the main failure modes of masonry walls; ii) shear failure could be viewed as the main failure mode of the model when the aspect ratio was less than 1.00; however, the flexural failure was considered to be the main failure mode of the model once the aspect ratio was greater than 1.00; iii) when a vertical load of 0.20 MPa was applied to the model, only flexural failure was observed, regardless of whether the aspect ratio of the model increased or decreased; the flexural shear mixed failure was captured within the range of 0.30 MPa– 0.50 MPa; the shear failure was the main failure mode within the range of 0.60 MPa– 0.70 MPa; and iv) the wall with an aspect ratio less than 1.00 could bear a higher horizontal load, and the increase in vertical load can significantly improve the horizontal load of the wall. …”

Force–displacement curves of M4. by Yukun Hu (427264)

“…The simulation results indicate that: i) the shear failure and flexural failure were the main failure modes of masonry walls; ii) shear failure could be viewed as the main failure mode of the model when the aspect ratio was less than 1.00; however, the flexural failure was considered to be the main failure mode of the model once the aspect ratio was greater than 1.00; iii) when a vertical load of 0.20 MPa was applied to the model, only flexural failure was observed, regardless of whether the aspect ratio of the model increased or decreased; the flexural shear mixed failure was captured within the range of 0.30 MPa– 0.50 MPa; the shear failure was the main failure mode within the range of 0.60 MPa– 0.70 MPa; and iv) the wall with an aspect ratio less than 1.00 could bear a higher horizontal load, and the increase in vertical load can significantly improve the horizontal load of the wall. …”

Summary of failure modes for all models. by Yukun Hu (427264)

“…The simulation results indicate that: i) the shear failure and flexural failure were the main failure modes of masonry walls; ii) shear failure could be viewed as the main failure mode of the model when the aspect ratio was less than 1.00; however, the flexural failure was considered to be the main failure mode of the model once the aspect ratio was greater than 1.00; iii) when a vertical load of 0.20 MPa was applied to the model, only flexural failure was observed, regardless of whether the aspect ratio of the model increased or decreased; the flexural shear mixed failure was captured within the range of 0.30 MPa– 0.50 MPa; the shear failure was the main failure mode within the range of 0.60 MPa– 0.70 MPa; and iv) the wall with an aspect ratio less than 1.00 could bear a higher horizontal load, and the increase in vertical load can significantly improve the horizontal load of the wall. …”

Force–displacement curves of M1. by Yukun Hu (427264)

“…The simulation results indicate that: i) the shear failure and flexural failure were the main failure modes of masonry walls; ii) shear failure could be viewed as the main failure mode of the model when the aspect ratio was less than 1.00; however, the flexural failure was considered to be the main failure mode of the model once the aspect ratio was greater than 1.00; iii) when a vertical load of 0.20 MPa was applied to the model, only flexural failure was observed, regardless of whether the aspect ratio of the model increased or decreased; the flexural shear mixed failure was captured within the range of 0.30 MPa– 0.50 MPa; the shear failure was the main failure mode within the range of 0.60 MPa– 0.70 MPa; and iv) the wall with an aspect ratio less than 1.00 could bear a higher horizontal load, and the increase in vertical load can significantly improve the horizontal load of the wall. …”