Metabolic Hormone FGF21 Is Induced in Ground Squirrels during Hibernation but Its Overexpression Is Not Sufficient to Cause Torpor by Bethany T. Nelson (106669)

“…<div><p>Hibernation is a natural adaptation that allows certain mammals to survive physiological extremes that are lethal to humans. …”

Table_1_Photosynthetic response of Chlamydomonas reinhardtii and Chlamydomonas sp. 1710 to zinc toxicity.DOCX by Di Zhan (14842687)

“…The μ and Chl-a content of C. reinhardtii decreased in the presence of 15  mg/L Zn, whereas those of Chlamydomonas sp. 1710 were unaffected by as high as 100  mg/L Zn. …”

Data Sheet 1_The association between lipid accumulation product and osteoporosis in American adults: analysis from NHANES dataset.docx by Huawen Pan (20899496)

“…Background<p>The Lipid Accumulation Product (LAP), a novel indicator of fat accumulation, reflects the distribution and metabolic status of body fat. …”

DataSheet_1_Morpho-physiological adaptations to drought stress in nitrogen-fixing and non-nitrogen-fixing plants.docx by Dongmin Zhao (9532941)

“…The diverse responses to drought among PFTs suggest a shift from N limitation to water limitation as SWC decreases.…”

Role of Type IV Pili in Predation by <i>Bdellovibrio bacteriovorus</i> by Ryan M. Chanyi (663440)

“…<div><p><i>Bdellovibrio bacteriovorus</i>, as an obligate predator of Gram-negative bacteria, requires contact with the surface of a prey cell in order to initiate the life cycle. …”

DataSheet_1_Benefits of Huang Lian mediated by gut microbiota on HFD/STZ-induced type 2 diabetes mellitus in mice.docx by Dan Li (106345)

“…</p>Methods<p>In this study, a type 2 diabetes mellitus (T2DM) mouse model was induced with a six-week high-fat diet (HFD) and a one-time injection of streptozotocin (STZ, 75 mg/kg). …”

Table_1_Benefits of Huang Lian mediated by gut microbiota on HFD/STZ-induced type 2 diabetes mellitus in mice.xlsx by Dan Li (106345)

“…</p>Methods<p>In this study, a type 2 diabetes mellitus (T2DM) mouse model was induced with a six-week high-fat diet (HFD) and a one-time injection of streptozotocin (STZ, 75 mg/kg). …”

Table 1_Prognostic significance of calcium-related genes in lung adenocarcinoma and the role of TNNC1 in macrophage polarization and erlotinib resistance.xlsx by Jian Feng (317890)

“…Down-regulation of TNNC1 decreased the IC₅₀ value of erlotinib in LUAD cells and inhibited macrophage M2 polarization.…”

Data_Sheet_1_Novel Prodiginine Derivatives Demonstrate Bioactivities on Plants, Nematodes, and Fungi.docx by Samer S. Habash (7351802)

“…Our infection assays revealed that the total number of developed H. schachtii individuals on A. thaliana was decreased to 50% in the presence of compounds 1 or 9. …”

Image 2_Prognostic significance of calcium-related genes in lung adenocarcinoma and the role of TNNC1 in macrophage polarization and erlotinib resistance.jpeg by Jian Feng (317890)

“…Down-regulation of TNNC1 decreased the IC₅₀ value of erlotinib in LUAD cells and inhibited macrophage M2 polarization.…”

Video_2_Activity-State Dependent Reversal of Ketamine-Induced Resting State EEG Effects by Clozapine and Naltrexone in the Freely Moving Rat.mp4 by Christien Bowman (12007985)

“…<p>Ketamine is a non-competitive N-Methyl-D-aspartate receptor (NMDAR) antagonist used in the clinic to initiate and maintain anaesthesia; it induces dissociative states and has emerged as a breakthrough therapy for major depressive disorder. …”

Suppressive effect of AMP-activated protein kinase on the epithelial-mesenchymal transition in retinal pigment epithelial cells by Ryo Matoba (1609)

“…<div><p>The epithelial-mesenchymal transition (EMT) in retinal pigment epithelial (RPE) cells plays a central role in the development of proliferative vitreoretinopathy (PVR). …”

Effect of connection density on SO dynamics. by Brianna Marsh (19179982)

“…Density is reduced by decreasing <i>P</i>, which denotes the probability of preserving a connection from the original dMRI-based connectivity. …”

Image_1_Photosynthetic response of Chlamydomonas reinhardtii and Chlamydomonas sp. 1710 to zinc toxicity.TIF by Di Zhan (14842687)

“…The μ and Chl-a content of C. reinhardtii decreased in the presence of 15  mg/L Zn, whereas those of Chlamydomonas sp. 1710 were unaffected by as high as 100  mg/L Zn. …”

Table_1_The Inhibitory Effect of GlmU Acetyltransferase Inhibitor TPSA on Mycobacterium tuberculosis May Be Affected Due to Its Methylation by Methyltransferase Rv0560c.docx by Changming Chen (275732)

“…Here, we found that TPSA (2-[5-(2-{[4-(2-thienyl)-2-pyrimidinyl]sulfanyl}acetyl)-2-thienyl]acetic acid) was a novel inhibitor for GlmU acetyltransferase activity (IC₅₀: 5.3 μM). …”

MCF7-luc-GFP-mCherry breast tumor response to administration of BPR0L075 observed by bioluminescence. by Li Liu (75607)

“…<p>(A, B) BLI of the same mouse as shown in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0043314#pone-0043314-g001" target="_blank">Figure 1</a> with images obtained within 15 mins after administration of luciferin s.c. immediately after the FLI; (C) Dynamic BLI showing evolution of signal intensity for the MCF7-luc-GFP-mCherry tumor shown in “A” over 40 minutes; respective curves show baseline (blue diamonds), together with 2 (red squares), 4 (green triangles), 6 (open circles) and 24 (yellow circles) hours after administration of drug carrier vehicle; (D) Dynamic BLI with respect to treatment with BPR0L075 (50 mg/kg i.p.): baseline (same as 24 hour time point in “A”, yellow circles); 2 hours after drug (red squares), 6 hours after drug (open circles) and 24 hours after drug (green triangles); (E) Normalized maximum bioluminescent signal observed in the first 15 mins post luciferin injection at each time point sequentially for individual mice over 24 hours with respect to carrier vehicle (n = 3, dashed lines) or drug (n = 3; solid lines). …”

Neither insulin nor VDAC modulate apoptosis triggered by detachment of HK II from mitochondria. by Federica Chiara (43469)

“…Cells were exposed for 1 hour to the stated concentrations of TAT-HK with or without pre-incubation with Debio 025 (DB, 8 µM), bongkrekate (BK, 100 µM) or Z.VAD-fmk (50 µM). Diagrams and percentages of the different cell populations are indicated as in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0001852#pone-0001852-g001" target="_blank">Fig. 1B</a>. …”

Image_2_Photosynthetic response of Chlamydomonas reinhardtii and Chlamydomonas sp. 1710 to zinc toxicity.TIF by Di Zhan (14842687)

“…The μ and Chl-a content of C. reinhardtii decreased in the presence of 15  mg/L Zn, whereas those of Chlamydomonas sp. 1710 were unaffected by as high as 100  mg/L Zn. …”

Endothelial progenitor cells in chronic obstructive pulmonary disease and emphysema by Margaret F. Doyle (449942)

“…<div><p>Endothelial injury is implicated in the pathogenesis of COPD and emphysema; however the role of endothelial progenitor cells (EPCs), a marker of endothelial cell repair, and circulating endothelial cells (CECs), a marker of endothelial cell injury, in COPD and its subphenotypes is unresolved. …”

Video_1_Activity-State Dependent Reversal of Ketamine-Induced Resting State EEG Effects by Clozapine and Naltrexone in the Freely Moving Rat.mp4 by Christien Bowman (12007985)

“…<p>Ketamine is a non-competitive N-Methyl-D-aspartate receptor (NMDAR) antagonist used in the clinic to initiate and maintain anaesthesia; it induces dissociative states and has emerged as a breakthrough therapy for major depressive disorder. …”