Detergent-free staining shows all Sdc constructs localize to the synapse. by Margaret U. Nguyen (3177789)

Piroxicam and vehicle control do not impact canine UC cells <i>in vitro</i>. by Jordon M. Inkol (11237604)

“…<p>Representative IC50 curves for piroxicam treatment of AXA, Orig, and SH cells show no dose dependent decrease in cell viability up to 1mM (A). …”

dFmr1 regulates heart rate. by Stefanie Mares Novak (826953)

“…<b>(B)</b> Loss of dFmr1 (<i>dFmr1</i>^<i>3/50M</i>, N = 16) results in a statistically significant decrease in heart rate when compared to wild type (<i>w</i>^<i>1118</i>, N = 10). …”

Kinetics of differential gene expression after rapid degradation of endogenous OGT in MEFs. by Sara Formichetti (20536052)

“…Differentially expressed genes with p-value < 10⁻⁵ and absolute log₂FC > 0.3 (i.e. 1.2-fold increase or decrease in expression) are colored in red and their number is indicated. …”

Test scores and ordering costs. by Jinghong Ma (1755838)

Uniportal VATS Right Lower Lobectomy and Lymphadenectomy: Step-by-Step by Hussein Elkhayat (4426768)

Optimization of performance and emission characteristics of CI engine fueled with Jatropha biodiesel produced using a heterogeneous catalyst (CaO) by Singh, A.

“…The heterogeneous transesterification delivered a yield of 81.6% at 5 wt% catalyst concentration and 12:1 methanol to oil molar ratio. …”
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mir-202-3p is associated with <i>Ppargc1a</i> and <i>Ppargc1b</i> degradation. by Timothy E. Sweeney (203800)

“…(C) mir-202-3p expression is negatively correlated with the mRNA levels of <i>Ppargc1a</i> (R² = 0.56) and <i>Ppargc1b</i> (R² = 0.83). (D) AML12 cells were transfected for 24 h with either mir-202-3p mimic or scramble siRNA, and then serum-starved to induce <i>Ppargc1a</i>. mir-202-3p causes a significant decrease in <i>Ppargc1a</i> mRNA. *, p<0.05, **, p<0.01. …”

Table_1_Tfam Knockdown Results in Reduction of mtDNA Copy Number, OXPHOS Deficiency and Abnormalities in Zebrafish Embryos.XLSX by Auke B. C. Otten (8965244)

“…Morphant embryos displayed abnormal development of the eye, brain, heart, and muscle, as well as a 50 ± 22% decrease in ATP production. Transcriptome analysis revealed a decrease in protein-encoding transcripts from the heavy strand of the mtDNA, and down-regulation of genes involved in haem production and the metabolism of metabolites, which appear to trigger increased rRNA and tRNA synthesis in the nucleoli. …”

Data_Sheet_1_Tfam Knockdown Results in Reduction of mtDNA Copy Number, OXPHOS Deficiency and Abnormalities in Zebrafish Embryos.PDF by Auke B. C. Otten (8965244)

“…Morphant embryos displayed abnormal development of the eye, brain, heart, and muscle, as well as a 50 ± 22% decrease in ATP production. Transcriptome analysis revealed a decrease in protein-encoding transcripts from the heavy strand of the mtDNA, and down-regulation of genes involved in haem production and the metabolism of metabolites, which appear to trigger increased rRNA and tRNA synthesis in the nucleoli. …”

Data_Sheet_3_Tfam Knockdown Results in Reduction of mtDNA Copy Number, OXPHOS Deficiency and Abnormalities in Zebrafish Embryos.PDF by Auke B. C. Otten (8965244)

“…Morphant embryos displayed abnormal development of the eye, brain, heart, and muscle, as well as a 50 ± 22% decrease in ATP production. Transcriptome analysis revealed a decrease in protein-encoding transcripts from the heavy strand of the mtDNA, and down-regulation of genes involved in haem production and the metabolism of metabolites, which appear to trigger increased rRNA and tRNA synthesis in the nucleoli. …”

Data_Sheet_2_Tfam Knockdown Results in Reduction of mtDNA Copy Number, OXPHOS Deficiency and Abnormalities in Zebrafish Embryos.pdf by Auke B. C. Otten (8965244)

“…Morphant embryos displayed abnormal development of the eye, brain, heart, and muscle, as well as a 50 ± 22% decrease in ATP production. Transcriptome analysis revealed a decrease in protein-encoding transcripts from the heavy strand of the mtDNA, and down-regulation of genes involved in haem production and the metabolism of metabolites, which appear to trigger increased rRNA and tRNA synthesis in the nucleoli. …”

Data_Sheet_4_Tfam Knockdown Results in Reduction of mtDNA Copy Number, OXPHOS Deficiency and Abnormalities in Zebrafish Embryos.PDF by Auke B. C. Otten (8965244)

“…Morphant embryos displayed abnormal development of the eye, brain, heart, and muscle, as well as a 50 ± 22% decrease in ATP production. Transcriptome analysis revealed a decrease in protein-encoding transcripts from the heavy strand of the mtDNA, and down-regulation of genes involved in haem production and the metabolism of metabolites, which appear to trigger increased rRNA and tRNA synthesis in the nucleoli. …”

Loss of intestinal epithelial Shh signaling deregulates intestinal crypt epithelial proliferation. by Jessica Gagné-Sansfaçon (571087)

“…Proliferation assays were performed by PCNA immunostaining (G and H, green labeling), with Evans blue serving as counterstain (red staining). Mutants displayed a decrease in cell proliferation as shown by a decrease in the number of PCNA-labeled proliferating cells (H) when compared to controls (G). …”

Displacement of site marker ligands bound to HSA in presence of increasing PS concentrations. by Shevin R. Feroz (468333)

“…Spectra marked as ‘a’, ‘b’, ‘c’ and ‘d’ refer to 10 µM BR, 10 µM HSA, 50 µM PS and PS–HSA (5∶1) complex, respectively. …”

Preferential down-regulation of miRNAs and overexpression of XY genes in GCKO testis samples by P18. by Anne R. Greenlee (304274)

“…In comparison to WT (n  = 3; RFC  = 1.0), significant reductions in GCKO miRNA expression were observed using qRT-PCR and P18 RNA from GCKO testes (n = 3). …”

Increased atherosclerotic lesion regression following blockade of JAM-C is concurrent with increased leukocyte emigration from plaques. by Paul F. Bradfield (3149529)

“…<p>48-hrs prior to transplantation or immediate sacrifice, all donor ApoE^-/- mice fed 12-wks of WD were injected with EdU (2mg/kg, i.p) to incorporate into DNA of monocyte precursors proliferating in the bone marrow. …”

Table_1_Schwann cell-derived exosomes ameliorate peripheral neuropathy induced by ablation of dicer in Schwann cells.DOCX by Lei Wang (6656)

Other glycines substitutions that destabilize BH4-Bcl-2’s by Giovanni Monaco (452223)

“…Data points represent means ± SEM. * indicates a statistically significant difference from vehicle control.…”

Impaired Myosin IIB recruitment at the growth cone of <i>TTL^−/−</i> neurons. by Séverine Marcos (265144)

“…(G) Quantification of Rac1 and Cdc42 GTPases activity in E12.5 wt and <i>TTL^−/−</i> hindbrains. …”