DataSheet_1_Membrane estrogen receptor-α contributes to female protection against high-fat diet-induced metabolic disorders.pdf by Aurélie Fabre (288323)

“…</p>Results<p>C451A-ERα genotype had no influence on body weight gain, adipose tissue accumulation and glucose tolerance in NCD-fed mice of both sexes followed up to 7 months of age, nor male mice fed a HFD for 12 weeks. In contrast, compared to WT-ERα littermates, HFD-fed C451A-ERα female mice exhibited: 1) accelerated fat mass accumulation, liver steatosis and impaired glucose tolerance; 2) whole-body insulin resistance, assessed by hyperinsulinemic-euglycemic clamps, and altered insulin-induced signaling in skeletal muscle and liver; 3) significant decrease in energy expenditure associated with histological and functional abnormalities of brown adipose tissue and a defect in thermogenesis regulation in response to cold exposure.…”

Inhibition of ROCK with Y-27632 causes relaxation of rat mesenteric collecting lymphatics. by Kristine H. Kurtz (548350)

“…</i> AMP/MaxD significantly decreased with 5–50 μM Y-27632. <i>E.</i> Y-27632 (25–50 μM) significantly decreased lymphatic tone. …”

Downstream molecular effects of knockdown of the expression of 5-HT_1B and 5-HT_1D receptors, on invasion and proliferation biomarkers in PaCa cells. by Nilgun Gurbuz (623605)

“…(Upper panel) Cells were transfected with 50 nM of indicated siRNAs, and after 72 h, the total RNA was extracted and the transcript levels of 5-HT_1B and 5-HT_1D were determined by standard RT-PCR as described in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0105245#s2" target="_blank">Materials and Methods</a>. …”

Stereological analysis of ChAT⁺ motor neurons. by Paolo d’Errico (494029)

<i>Npr2</i> mutants show normal auditory responses. by Cindy C. Lu (669417)

Inflammatory effectors are detected in the conjunctiva and the draining lymph nodes of TSP-1 null mice. by Laura Contreras-Ruiz (461999)

“…<p>Conjunctiva tissue and cervical lymph node cells were collected from WT and TSP-1 null mice at 6, 8, and 12 weeks (n=3 each). …”

Ama controls the pool of myoblast number independently of Nrt. by Blandine Moucaud (11844047)

“…<p><b>(A–D)</b> L3 leg discs immunostained for Twi (magenta). …”

Table 1_Causality of circulating vitamins on infectious diseases: integrating Mendelian randomization and in vivo evidence.docx by Aling Tang (17523700)

VEGFR1 and VEGFR2 Involvement in Extracellular Galectin-1- and Galectin-3-Induced Angiogenesis by Nicky D'Haene (422477)

Genome-Wide Negative Feedback Drives Transgenerational DNA Methylation Dynamics in Arabidopsis by Tasuku Ito (728549)

Effects of different parameters on Rnf2 binding. by Nikolaj Dietrich (181521)

“…(B) Scatter diagram showing the Rnf2 signal for the Rest peaks with either relative low (blue color) or high (red color) levels of Suz12 (left panel) or H3K27Me3 (right panel) in the <i>Wt</i> versus <i>Rest−/−</i> mES cells. …”

Spinal cord parasitism. by André Luis Bombeiro (121574)

“…For the absolute quantification, sample values were fitted into a standard curve, constructed from a pattern sample with known number of copies of <i>T. cruzi</i> 18S rRNA. IL-12p40KO mice presented an ascending parasitism while WT ones managed to constrain the infection by the third week, thus decreasing the parasitic load after the fifth week. …”

The morphogenesis and development of VM dopaminergic neurons is disturbed in <i>Dkk1^{<b>−/−</b>}</i> embryos. by Diogo Ribeiro (230483)

“…(B) Immunohistochemistry for TH in midbrain sections of <i>Dkk1^−/−</i> embryos revealed a decrease of aberrantly distributed dopaminergic neurons (upper panels) or an almost absence of dopaminergic neurons (bottom panels). …”

Emodin suppresses HG-induced cFLIP generation but not repressing its activation and increasing degration. by Junjie Gao (545578)

“…<p>(<b>a, b</b>) MCs were cultured in HG media and treated with 50 μM emodin for indicated times. …”

Brain-specific disruption of OPA1 processing. by Victoria L. Patterson (678436)

Knockout of PHD2 reduces HFD-induced NF-κb activation and macrophage infiltration in HFD mice. by Heng Zeng (324703)

Changes in the GRF, duty factor and mechanical energy fluctuations with increasing speed. by P. J. Bishop (4219759)

<i>N. meningitidis</i> infection of HBMEC causes degradation of occludin. by Alexandra Schubert-Unkmeir (154787)

“…A weak specific occludin fragment with an apparent molecular mass of 50–kDa is generated during infection at 24 h p.i. …”

Comparison between patients and volunteers for aortic distensibility at rest and exercising. by Paul Habert (6166844)

Histopathological alterations in the spleen and liver. by Sergio Cuervo-Escobar (678682)