FIGURE 1 from D-2-HG Inhibits <i>IDH1^mut</i> Glioma Growth via FTO Inhibition and Resultant m6A Hypermethylation by Sean T. Pianka (18237413)

“…<b>A,</b><i>IDH1^mut</i> patient gliomas manifested RNA m6A hypermethylation, <i>IDH1^mut</i> (<i>n</i> = 12) versus <i>IDH1^wt</i> (<i>n</i> = 12; <i>P</i> ≤ 0.04). …”

Turbocharging Matched Molecular Pair Analysis: Optimizing the Identification and Analysis of Pairs by Iva Lukac (593803)

Proteasome Inhibitors Block DNA Repair and Radiosensitize Non-Small Cell Lung Cancer by Kyle R. Cron (455028)

“…Proteasome inhibition resulted in an 80–90% decrease in homologous recombination (HR), a 50% decrease in expression of NF-κB-inducible HR genes <i>BRCA1</i> and <i>FANCD2</i>, and a reduction of BRCA1, FANCD2 and RAD51 ionizing radiation-induced foci. …”

Y-27632 treatment of P19 cells inhibits the differentiation of primitive endoderm. by Roman J. Krawetz (309735)

“…FACS analysis demonstrates a significant decrease in GATA-6 and Troma-1 positive cells with Y-27632 present (K). …”

Menthol and eugenol as natural anesthetics for early juveniles of curimba by Elias Fernandes de Medeiros Junior (4832202)

“…Increased concentrations led to a decrease in recuperation time. The concentrations between 50 to 70 mg of eugenol L−1 provided the lowest induction times; however, recovery time was not affected by eugenol concentrations. …”

Waterfall plot showing the quantitative changes in ER, PR, and Ki-67 expression. by Yuqin Ding (623253)

“…(A) ER discordance rate: 10.4% (50/482) of patients, including 36 (7.5%) patients with positive-to-negative conversion and 14 (2.9%) patients with negative-to-positive conversion; (B) PR discordance rate: 17.0% (82/482) of patients, including 57 (11.8%) patients with positive-to-negative conversion and 25 (5.2%) patients with negative-to-positive conversion; (C) Ki-67 discordance rates: 50.4% (243/448) of patients had decreased expression and 27.0% (130/448) of patients had increased expression.…”

Downregulation of COP9 signalosome subunits differentially affects the CSN complex and target protein stability-0 by Andreas Peth (85734)

Positive feedback in <i>CLN2</i> activation and the coherence of entry into Start. by Debashis Barik (3389255)

“…</b> As the rate constant for phosphorylation of Whi5 by Cln1,2 (i.e., the strength of the Cln1,2-mediated positive feedback loop) is progressively decreased (in panels C1-C5), the coherence of gene activation upon entry into Start decreases. …”

Downregulation of COP9 signalosome subunits differentially affects the CSN complex and target protein stability-5 by Andreas Peth (85734)

Effects of endogenous prostanoids and selective agonists on the beating rate of neonatal rat cardiomyocytes. by Hakima Mechiche (308181)

“…“bradyarrhythmia” indicated a decrease of more than 50%; “tachyarrhythmia” indicated an increase of more than 50% with chaotic, asynchronous, activity of the myocytes <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0045273#pone.0045273-Li1" target="_blank">[13]</a>; <i>n</i> is the number of preparations on which brady- or tachy-arrhythmia was observed.…”

pQTL analysis of IFN-α and IFN-γ receptor levels and responses. by Christian Lundtoft (4068679)

“…Blue indicates a decrease in minor allele carriers, while red indicates an increase in minor allele carriers. …”

Table_6_Biological, Behavioral and Physiological Consequences of Drug-Induced Pregnancy Termination at First-Trimester Human Equivalent in an Animal Model.DOCX by Christina Camilleri (6751091)

“…Following drug/vehicle administration, only the pregnancy termination group (pregnant, drug) displayed a significant decrease in body weight, food intake, locomotor activity-related behaviors and home-cage activity relative to the control group (non-pregnant, vehicle). …”

Table_10_Biological, Behavioral and Physiological Consequences of Drug-Induced Pregnancy Termination at First-Trimester Human Equivalent in an Animal Model.DOCX by Christina Camilleri (6751091)

“…Following drug/vehicle administration, only the pregnancy termination group (pregnant, drug) displayed a significant decrease in body weight, food intake, locomotor activity-related behaviors and home-cage activity relative to the control group (non-pregnant, vehicle). …”

Table_12_Biological, Behavioral and Physiological Consequences of Drug-Induced Pregnancy Termination at First-Trimester Human Equivalent in an Animal Model.DOCX by Christina Camilleri (6751091)

“…Following drug/vehicle administration, only the pregnancy termination group (pregnant, drug) displayed a significant decrease in body weight, food intake, locomotor activity-related behaviors and home-cage activity relative to the control group (non-pregnant, vehicle). …”

Table_9_Biological, Behavioral and Physiological Consequences of Drug-Induced Pregnancy Termination at First-Trimester Human Equivalent in an Animal Model.DOCX by Christina Camilleri (6751091)

“…Following drug/vehicle administration, only the pregnancy termination group (pregnant, drug) displayed a significant decrease in body weight, food intake, locomotor activity-related behaviors and home-cage activity relative to the control group (non-pregnant, vehicle). …”

Table_7_Biological, Behavioral and Physiological Consequences of Drug-Induced Pregnancy Termination at First-Trimester Human Equivalent in an Animal Model.DOCX by Christina Camilleri (6751091)

“…Following drug/vehicle administration, only the pregnancy termination group (pregnant, drug) displayed a significant decrease in body weight, food intake, locomotor activity-related behaviors and home-cage activity relative to the control group (non-pregnant, vehicle). …”

Table_8_Biological, Behavioral and Physiological Consequences of Drug-Induced Pregnancy Termination at First-Trimester Human Equivalent in an Animal Model.DOCX by Christina Camilleri (6751091)

“…Following drug/vehicle administration, only the pregnancy termination group (pregnant, drug) displayed a significant decrease in body weight, food intake, locomotor activity-related behaviors and home-cage activity relative to the control group (non-pregnant, vehicle). …”

Table_15_Biological, Behavioral and Physiological Consequences of Drug-Induced Pregnancy Termination at First-Trimester Human Equivalent in an Animal Model.DOCX by Christina Camilleri (6751091)

“…Following drug/vehicle administration, only the pregnancy termination group (pregnant, drug) displayed a significant decrease in body weight, food intake, locomotor activity-related behaviors and home-cage activity relative to the control group (non-pregnant, vehicle). …”

Image_1_Biological, Behavioral and Physiological Consequences of Drug-Induced Pregnancy Termination at First-Trimester Human Equivalent in an Animal Model.TIF by Christina Camilleri (6751091)

“…Following drug/vehicle administration, only the pregnancy termination group (pregnant, drug) displayed a significant decrease in body weight, food intake, locomotor activity-related behaviors and home-cage activity relative to the control group (non-pregnant, vehicle). …”

Table_11_Biological, Behavioral and Physiological Consequences of Drug-Induced Pregnancy Termination at First-Trimester Human Equivalent in an Animal Model.DOCX by Christina Camilleri (6751091)

“…Following drug/vehicle administration, only the pregnancy termination group (pregnant, drug) displayed a significant decrease in body weight, food intake, locomotor activity-related behaviors and home-cage activity relative to the control group (non-pregnant, vehicle). …”