Selective TASK‑1 Inhibitor with a Defined Structure–Activity Relationship Reduces Cancer Cell Proliferation and Viability by Bárbara Arévalo (4053358)

“…Mutation of seven residues to A (I118A, L122A, F125A, Q126A, L232A, I235A, and L239A) markedly decreased the F3-induced inhibition of TASK-1 channels, consistent with the molecular modeling predictions. …”

Somatosensory evoked potentials produced by peroneal nerve stimulation at different spinal cord levels. by Jose R. Eguibar (8563227)

The corticospinal pathway is more susceptible to iterative stimulation and have lower conduction velocity in <i>taiep</i> rats. by Jose R. Eguibar (8563227)

“…<b>B)</b> The conduction velocity of the corticospinal tract significantly decreased in <i>taiep</i> to 13.7 m/s (blue bar) with respect to WT with 42.9 m/s (empty bar; t ₍₁₂₎, = 42; **<i>P<</i> 0.05). …”

p12 carries a signal peptide that is cleaved via the signal peptidase complex (SPC). by Florian Simon (5387228)

Inhibition of p12 cleavage impairs HTLV-1 cell-to-cell transmission of chronically infected MT-2, but not C91-PL cells. by Florian Simon (5387228)

LPS administration demonstrated a significant decrease in the protein expression of both claudin-1 and occludin in BF fed mice as compared to control mice. by Valentina Di Caro (510473)

A-C. Inhibitors of cell death (zVAD-fmk and Nec-1) do not rescue the BMP2-induced decrease in cell numbers. by Charlotte Lagler (4017212)

Effect of MF (2 MT, 50 Hz) on VEGFR expression and activation. by Simona Delle Monache (402973)

“…<p>Protein of equal quantity was separated by 8% SDS-page and electroblotted on to a PVDF membrane. Representative blots show effects exerted by MF (2 mT, 50 Hz) on VEGFR2 total expression and phosphorylation after 1 h, 6 h and 12 h of exposure A). …”

Partial unwinding of backbone modified DNA substrates by BACH1-WT helicase by Rigu Gupta (22923)

ChemRich enrichment of the top 50 most changed metabolites for SCD. by Juliette Cooke (11402543)

A small group of plains zebra taken at a real-world equivalent of 16.4 m as they may appear to a human (a,c,e) and lion (b,d,f) under photopic (bright; daylight), mesopic (dim; dus... by Amanda D. Melin (270203)

50% reduction of kinesin-1 or dynein is sufficient to perturb neuronal growth. by Gary J. Iacobucci (192833)

“…<p>(<b>A</b>) Representative neuronal cultures expressing APP-YFP and APP-YFP with 50% genetic reduction of either kinesin-1 or dynein are shown at day 1 and day 2. …”

Table_1_Decrease in Admissions and Change in the Diagnostic Landscape in a Newborn Care Unit in Northern Ghana During the COVID-19 Pandemic.DOC by Alhassan Abdul-Mumin (5986151)

“…</p><p>Conclusion: We observed a marked decrease in admissions and change in the diagnosis landscape and related mortality during the pandemic. …”

Dependence of seizure transition times on (<i>dν</i>_<i>se</i>/<i>dt</i>)^−1/2 with the default parameters as in Table 1 and Δ ranges from 2 s to 50 s. by F. Deeba (8661837)

Neural networks classify states which differ in neuronal activity levels using ensembles of neurons that increase/decrease their activity in each state. by Nicholas A. Frost (10739821)

“…As a result, there is an increase (neurons 51:100) or decrease (neurons 1:50) in activity levels in State B compared to State A. …”

The increased <i>in vitro</i> phagocytic activity of resKCs and recMφs against FITC-<i>E</i>. <i>coli</i> and the decreased TNF-α production by LPS-stimulated liver MNCs following... by Takuya Ishikiriyama (6735674)

<i>Vps34</i> KO MEFs show a decrease in LC3 conjugation and LC3 puncta formation upon starvation. by Kelly Devereaux (466106)

In Vitro Screening for ToxCast Chemicals Binding to Thyroxine-Binding Globulin by Stephanie A. Eytcheson (4284421)

“…EPA’s ToxCast phase1_v2, phase 2, and e1k libraries for competitive binding to one of the carrier proteins, thyroxine-binding globulin. Initial screening at a single high concentration of 100 μM identified 714 chemicals that decreased signal of the bound fluorescent ligand by 20% or higher. …”

Table S1 - Decreased Prevalence of Lymphatic Filariasis among Diabetic Subjects Associated with a Diminished Pro-Inflammatory Cytokine Response (CURES 83) by Vivekanandhan Aravindhan (247245)

Kaplan-Meier for decreases in CD4 T-cells (A) and rebound of viral load (VL) (B) in HIV-infected patients after treatment interruption by Elena Seoane (90182)