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Identification of an amino-terminus determinant critical for ryanodine receptor/Ca2+ release channel function.
Published 2020“…The cardiac ryanodine receptor (RyR2), which mediates intracellular Ca2+ release to trigger cardiomyocyte contraction, participates in development of acquired and inherited arrhythmogenic cardiac disease. …”
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Decreased number of acute appendicitis cases in pediatric population during the COVID-19 pandemic: Any link?
Published 2020“…The reasons behind the decrease in AA frequency during the COVID-19 pandemic remain unclear. …”
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Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle
Published 2023“…We found both young and aged HSA-mUCP1 mice had decreased advanced glycation endproducts (AGEs) formed from MG, lysine-derived Nε(1-carboxyethyl)lysine (CEL) and arginine-derived hydroimidazolone, MG-H1, whereas protein glycation by glucose forming Nε-fructosyl-lysine (FL) was increased ca. 2-fold, compared to wildtype controls. …”
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Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle
Published 2023“…We found both young and aged HSA-mUCP1 mice had decreased advanced glycation endproducts (AGEs) formed from MG, lysine-derived Nε(1-carboxyethyl)lysine (CEL) and arginine-derived hydroimidazolone, MG-H1, whereas protein glycation by glucose forming Nε-fructosyl-lysine (FL) was increased ca. 2-fold, compared to wildtype controls. …”
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Quality improvement can decrease blood delivery turnaround time: Evidence from a single tertiary-care academic medical center
Published 2018“…The transport time significantly decreased from an initial majority of > 15 mins duration, to a majority of < 15 mins transport time after the second audit; there was a 50% improvement in 30 mins response time; and the percentage of requests processed in < 10 mins were significantly higher after the second audit. …”
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12/15-Lipoxygenase-Derived Lipid Metabolites Induce Retinal Endothelial Cell Barrier Dysfunction: Contribution of NADPH Oxidase
Published 2013“…The purpose of the current study was to evaluate the effect of 12/15- lipoxygenase (12/15-LOX) metabolites on retinal endothelial cell (REC) barrier function. …”
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Novel thiazolones for the simultaneous modulation of PPARγ, COX-2 and 15-LOX to address metabolic disease-associated portal inflammation
Published 2025“…The two most effective 15-LOX inhibitors, 2a and 2b, exhibited 69 % and 57 % of quercetin's action, respectively. …”
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Synergistic effect of expanded graphite, diammonium phosphate and Cloisite 15A on flame retardant properties of EVA and EVA/wax phase change blends
Published 2015“…It was, however, found that there was little separation of the EG platelets, although the presence of wax caused a decrease in the sizes of the EG agglomerates. The thermal stability of EVA and the EVA/wax blend improved in the presence of EG and its combination with Cloisite 15A and DAP.…”
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A lipidomic screen of hyperglycemia-treated HRECs links 12/15-Lipoxygenase to microvascular dysfunction during diabetic retinopathy via NADPH oxidase
Published 2015“…Fluorescein angiography and retinal albumin leakage showed a significant decrease in retinal hyperpermeability in streptozotocin-induced diabetic mice lacking 12/15-LOX compared with diabetic WT mice. …”
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DEVELOPMENT AND EVALUATION OF VIRTUAL REALITY EXERGAMES FOR UPPER LIMB AMPUTEE REHABILITATION
Published 2024“…Immersive VR environments were integrated with Electromyography (EMG) for interpreting muscle signals, haptic feedback to enhance the sense of realism, and 3D pose estimation for precise performance assessment through kinematics analysis. …”
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Possible Ionic Effects of NaCl on Two Mexican Wheat Cultivars
Published 2005“…The ionic agents, NaCl and Na2SO+, decreased K* and Ca2* in the leaves, while PEG had little effect on leaf iontent of r* ana- Ca2i lif in.r. ug"",t increased phosphorus in leaves of both cultivars, but PEG had the smallest effect. …”
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Calmodulin Mutations Associated with Congenital Cardiac Disease Display Novel Biophysical and Biochemical Characteristics
Published 2018“…In contrast, in the presence of Ca2+, there was a significant decrease in the stability of the five proteins following the order CaMWT> CaMN98I > CaMD132E > CaMQ136P > CaMD134H. …”
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In vitro effects of hydrogen peroxide on rat uterine contraction before and during pregnancy
Published 2018“…Results In both term-pregnant and non-pregnant uterine strips, H 2 O 2 elicited a biphasic response, consisting of a transient contraction followed by a persistent decrease in spontaneously generated contractions, contractions induced by oxytocin, and contractions induced by high Ca +2 (all P< 0.01, compared with controls) in a concentration-dependent manner. …”
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Divergent Biochemical Properties and Disparate Impact of Arrhythmogenic Calmodulin Mutations on Zebrafish Cardiac Function
Published 2024“…Furthermore, circular dichroism spectroscopy experiments using recombinant CaM proteins reveals a decreased structural stability of the four mutants compared to the wild-type CaM protein in the presence of Ca2+. …”
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Effect Of The Apical Ectodermal Ridge On Mitotic Index In Hind Limb Bud Mesenchyme In Bufo Regularis
Published 1991“…By AER removal at stage 51, it reformed showing normal appearance (70% of cases), and a pronounced decrease in limb size was also observed. Mesenchyme MI (stage 51) was decreased 30% distally and 20% proximally, then distal mesenchyme revealed another decrease (15%), and by stage 52, MI increased distally (20%). …”
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Effect of outdoor temperature on the power-conversion efficiency of newly synthesized organic photosensitizer based dye-sensitized solar cells
Published 2018“…The decrease in efficiency can be attributed to decrease in open-circuit voltage of cells. …”
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