Protein arginine methyltransferase 5 (PRMT5) promotes survival of lymphoma cells via activation of WNT/B-catenin and AKT/GSK3B proliferative signaling حسب Chung, Jihyun

"…We show that PRMT5 stimulates WNT/B-CATENIN signaling through direct epigenetic silencing of pathway antagonists, AXIN2 and WIF1, and indirect activation of AKT/GSK3 signaling.PRMT5 inhibition with either shRNA-mediated knockdown or a specific small molecule PRMT5 inhibitor, CMP-5, not only leads to derepression of WNT antagonists and decreased levels of active phospho-AKT (Thr-450 and Ser-473) and inactive phospho- GSK3B (Ser-9) but also results in decreased transcription of WNT/B-CATENIN target genes, CYCLIN D1, c-MYC, and SURVIVIN, and enhanced lymphoma cell death. …"
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Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle حسب Jinit, Masania

"…In aged HSA-mUCP1 mice, urinary MG-derived AGEs/FL ratio was decreased ca. 60% whereas there was no change in CML/FL ratio – a marker of oxidative damage. …"
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Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle حسب Jinit, Masania

"…In aged HSA-mUCP1 mice, urinary MG-derived AGEs/FL ratio was decreased ca. 60% whereas there was no change in CML/FL ratio – a marker of oxidative damage. …"
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Multifunctional self-healing polymeric nanocomposite coatings for corrosion inhibition of steel حسب Ubaid F.

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Evidence of two mechanisms involved in Bacillus thuringiensis israelensis decreased toxicity against mosquito larvae: Genome dynamic and toxins stability حسب Elleuch, Jihen

"…This bacterium is characterized by a dynamic genome able to win or lose genetic materials which leads to a decrease in its effectiveness. …"
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Investigation of solar PV performance under Doha weather using a customized measurement and monitoring system حسب Touati, Farid

"…Results predict that the maximum power output from a Poly-crystalline panel decreases by around 30% for a dust exposure of five months. …"
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Effect of octylphenol polyethylene oxide on the corrosion inhibition of steel in 0.5 M H2SO4 حسب Algaber, A.S

"…The experimental data were fitted with the Flory-Huggins isotherm at a molecular ratio of 5:1. The Gibbs energy of adsorption decreases with the temperature. …"
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A 5-year trend in the use of sodium-glucose co-transporter 2 inhibitors and other oral antidiabetic drugs in a Middle Eastern country حسب Zaghloul, Nancy

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Simulation and experimental study of underwater dissimilar friction-stir welding between aluminium and steel حسب Eyvazian, Arameh

"…Theeffects of processing parameters on the formation of intermetallic compounds (IMCs) atthe Al/St interface, microstructural characteristics, and mechanical property of dissimilarweldments were studied and addressed. By decreasing tool rotational speed (w), increas-ing traverse velocity (v), and employing cooling medium, peak temperature continuouslyreduced (down to ?…"
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A BRET-based Mpro biosensor containing a nanobody and tandem cleavage sites shows an increased cleavage rate حسب Geethakumari, Anupriya M

"…Here, we report the engineering of a Bioluminescence Resonance Energy Transfer (BRET)-based SARS-CoV-2 main protease (Mpro) biosensor containing the Mpro N-terminal autocleavage sequence in tandem and a nanobody that shows an enhanced rate of Mpro-mediated proteolytic cleavage. …"
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Effects of SARS-CoV-2 Alpha, Beta, and Delta variants, age, vaccination, and prior infection on infectiousness of SARS-CoV-2 infections حسب Qassim, Suelen H.

"…Using the cycle threshold (Ct) value of an RT-qPCR-positive test to proxy the inverse of infectiousness, we investigated infectiousness of SARS-CoV-2 infections by variant, age, sex, vaccination status, prior infection status, and reason for testing in a random sample of 18,355 RT-qPCR-genotyped infections. …"
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Mechanical and Electromagnetic Properties of Self-Compacted Geopolymer Concretes With Nano Silica and Steel Fiber Additives حسب Hasar, Ugur Cem

"…Mechanical and electromagnetic properties (over 2-16 GHz) of self-compacted geopolymer concrete (SCGC) samples with different amounts of nanosilica (NS) and steel-fiber (SF) have been examined. …"
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L5 Spinal Nerve Axotomy Induces Distinct Electrophysiological Changes in Axotomized L5- and Adjacent L4-Dorsal Root Ganglion Neurons in Rats . حسب Djouhri, Laiche

"…Consistent with this hypothesis, we found (7 days post-SNA), in SNA rats with established pain hypersensitivity, slower AP kinetics in axotomized L5-neurons and faster AP kinetics in L4-nociceptive neurons including decreased rise time in Aδ-and Aβ-fiber nociceptors, and after-hyperpolarization duration in Aβ-fiber nociceptors. …"
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Pollution Characteristics of Particulate Matter (PM2.5 and PM10) and Constituent Carbonaceous Aerosols in a South Asian Future Megacity حسب Aslam, Afifa

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Mechanical Properties of Concrete Made with Electric Wires, Steel Fibers, Basalt Fibers and Polypropylene Fibers حسب Murad, Yasmin Zuhair

"…Fibers are added to the concrete mix in three different percentages (48, 32 and 16 kg/m3 for steel and wire fibers) and (2, 4 and 8 kg/m3 for basalt and polypropylene fibers). …"
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An Improved Fault Tolerant Five-Phase Induction Machine Using A Combined Star/Pentagon Single Layer Stator Winding Connection حسب Abdel-Khalik, Ayman S.

"…For the healthy case, the machine is similar to a conventional star connected five-phase machine. …"
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Effects of a single dose of ivermectin on viral and clinical outcomes in asymptomatic sars-cov-2 infected subjects: A pilot clinical trial in lebanon حسب Samaha, Ali A.

"…Methods: A randomized controlled trial was conducted in 100 asymptomatic Lebanese subjects that have tested positive for SARS-CoV2. …"
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The impact of COVID-19 pandemic lockdown on smoking habits and lifestyle: A cross-sectional study حسب Khamees, Almu'atasim

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Evidence by ac-conductivity for the higher mobility of boron (over aluminium)-associated Brønsted sites in boron-modified HZSM-5 حسب Sayed, Moein B.

"…A correlation ac-conductivity analysis is performed at 102–105 Hz, 373–613 K and 0.8 V for characterizing the effect of increasing boron incorporation in HZSM-5 lattice on altered electric features in BZSM-5 samples of similar origin. …"
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Serum Vitamin D Concentration ≥75 nmol/L Is Related to Decreased Cardiometabolic and Inflammatory Biomarkers, Metabolic Syndrome, and Diabetes; and Increased Cardiorespiratory Fitn... حسب Ganji, Vijay

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