Pertussis specific IgG levels decrease with time. by Inonge van Twillert (503888)

3D interactions between the ligand and the protein_DNA complex in the first (C1) and second (C2) clusters. by Ahmed A. Gaber (13302308)

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Binding of amsacrine with DNA-Topo II complex. by Ahmed A. Gaber (13302308)

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The center of mass distances between the protein-DNA complex and the ligand (Blue line), and the protein and DNA (red line). by Ahmed A. Gaber (13302308)

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Fig 12 - by Ahmed A. Gaber (13302308)

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The number of clusters, number of interactions, and their types between the ligand and protein_DNA complex. by Ahmed A. Gaber (13302308)

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Binding of compound 17 with DNA-Topo II complex. by Ahmed A. Gaber (13302308)

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Fig 4 - by Ahmed A. Gaber (13302308)

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Some reported DNA intercalators and their basic pharmacophoric features. by Ahmed A. Gaber (13302308)

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The contributions from the different energy components of MM-GBSA. by Ahmed A. Gaber (13302308)

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Binding of compound 19 with DNA-Topo II complex. by Ahmed A. Gaber (13302308)

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The immunoblotting of BAX and Bcl-2 (Normalized to β-actin). by Ahmed A. Gaber (13302308)

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The antiproliferative activities of the tested compounds toward HepG2, and HCT‐116 cell lines, Topo II activity, and DNA‐intercalating affinity. by Ahmed A. Gaber (13302308)

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The docking binding free energies (ΔG) of the synthesized compounds with DNA-topoisomerase II complex. by Ahmed A. Gaber (13302308)

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The rationale of molecular design of new DNA-intercalators. by Ahmed A. Gaber (13302308)

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mTOR inhibition decreased mitochondrial mass. by Piero Dalle Pezze (622889)

“…Gradual mTOR specific inhibition from 0% (black, control) to 90% predicted a decrease in mitochondrial mass due to the perturbation of the population of old mitochondria. …”

Mitochondrial dysfunction is driven by decreased mitochondrial dynamics. by Piero Dalle Pezze (622889)

“…Example images from these areas over 140 s are shown below with the detected fusion and fission events highlighted with white and yellow arrows respectively. A timelapse movie containing the full dataset from a control and senescent cell are available in <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1003728#pcbi.1003728.s027" target="_blank">Movie S1</a>. …”

Decreased Sho levels in ScN2a-Sho cells. by Joel C. Watts (195735)

“…(<b>C</b>) Quantification of Sho levels in ScN2a-Sho-1 (<i>n</i> = 10) and ScN2a-Sho-2 (<i>n</i> = 5) subclones revealed a significant decrease of 40–45% compared to the uninfected parental cell line (<i>n</i> = 15) (***<i>P</i><0.001).…”

Top k-NN clusters of metabolites decreased at 4 hours. by Zarazuela Zolkipli-Cunningham (5234186)

Top k-NN cluster of metabolites decreased at 30 minutes. by Zarazuela Zolkipli-Cunningham (5234186)