Discovery of <i>N</i>‑((3<i>S</i>,4<i>S</i>)‑4-(3,4-Difluorophenyl)piperidin-3-yl)-2-fluoro-4-(1-methyl‑1<i>H</i>‑pyrazol-5-yl)benzamide (Hu7691), a Potent and Selective Akt Inhibitor That Enables Decrease of Cutaneous Toxicity by Jinxin Che (791250)

Discovery of <i>N</i>‑((3<i>S</i>,4<i>S</i>)‑4-(3,4-Difluorophenyl)piperidin-3-yl)-2-fluoro-4-(1-methyl‑1<i>H</i>‑pyrazol-5-yl)benzamide (Hu7691), a Potent and Selective Akt Inhibitor That Enables Decrease of Cutaneous Toxicity by Jinxin Che (791250)

Inclusion of SRRM4-regulated exons is decreased in tumors and cancer cell lines. by Sarah A. Head (6066398)

“…(B) SRRM4 target exons with respect to their average PSI in normal tissues. Red points are exons with PSI decreasing by at least 5% in at least 1 tumor type. …”

Folding and stability of GDAP1 as affected by CMT mutations. by Aleksi Sutinen (10039145)

Subjects:

S16 Fig - by Jordan K. Abbott (8934239)

Binding of <i>PC3/Tis21</i> to the <i>Id3</i> promoter and corresponding decrease of <i>Id3</i> mRNA. by Stefano Farioli-Vecchioli (256006)

“…(<b>B</b>) ChIP analysis of <i>PC3</i> binding to the <i>Id3</i> promoter in PC12 cells, treated as shown in (<b>A</b>). A scheme above the graph describes the <i>Id3</i> gene and the promoter region analyzed, 700 nt 5′ to the transcription start. …”

Fig 5 - by Xiaoqing Chen (89898)

Decrease in number of activated macrophages in demyelinated nerves subjected to 1hr ES. by Nikki A. McLean (643606)

“…Note: ES results in a significant decrease in the ED-1 IF 10d post-LPC (5d post-ES; K) and 12d post-LPC (7d post-ES; N) relative to LPC only in a pattern suggestive of movement toward lateral edges and egress (arrow). …”

Odds of being underweight (A), overweight (B) or obese (C) according to restricted cubic splines (RCSs) regression. by Sheikh Arafat Rahman (21799685)

Fig 5 - by Evelyn Medawar (9774392)

An enhanced clot growth rate before in vitro fertilization decreases the probability of pregnancy by A. N. Balandina (6729380)

Average self-reported physical health ratings before or during the COVID-19 pandemic among individuals who engaged during the pandemic in more than 3 (A), 4 (B), or 5 (C) positive... by Elie Mulhem (22537863)

CXCR4 blockade decreased the percentage of PD-1 expressing adaptive immune cells in sepsis. by Kimberly M. Ramonell (4678906)

“…<p><b>(A-B)</b> Representative flow plots (gated on CD3 cells) demonstrating PD-1 expression in CD4⁺ T cells and CD8⁺ T cells. …”

Predicted metabolite levels for each reaction intermediate shown in Figure 7 under conditions in which the NAD+:NADH ratio is 31 (Bennett et al. [26]), or decreased by either 0.1-f... by William R. Cannon (608586)

Effects of Kylo-0603 on body weight, organ weight, and body fat content. by Xueqin lu (22250795)

Loss of virulence in the SIN kinase mutants is characterized by decreased fungal burden and host response to infection. by Ana Camila Oliveira Souza (8180958)

“…<p><b>A)</b> Analysis of fungal burden by qPCR at day +4 post inoculation. …”

Cell cycle progression of hMSCs following X-rays irradiation, under normoxia (21% O2) and physioxia (3% O2) growing conditions. by Séverine Cruet-Hennequart (716700)

Influence of Acidic pH on Hydrogen and Acetate Production by an Electrosynthetic Microbiome by Edward V. LaBelle (608387)

“…Cyclic voltammetry revealed a 250 mV decrease in hydrogen overpotential and a maximum current density of 12.2 mA/cm² at −765 mV (0.065 mA/cm² sterile control at −800 mV) by the <i>Acetobacterium</i>-dominated community. …”

Effect of Kylo-0603 drug on the reversal of steatosis and inhibition of fibrotic process in liver tissues of the MASH mouse models (F2 ~ 3), analyzed by SHG/TPEF microscopy combine... by Xueqin lu (22250795)

Competitive DNA fragment containing the A allele decreased MMP3-A’s binding with transcription factor. by Cong Huai (385128)