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Metformin attenuates V-domain Ig suppressor of T-cell activation through the aryl hydrocarbon receptor pathway in Melanoma: In Vivo and In Vitro Studies
Published 2021“…This study aims to investigate the inhibitory effect of metformin on VISTA via AHR in melanoma cells (CHL-1, B16) and animal models. VISTA and AHR levels were assessed by qPCR, Western blot, immunofluorescence microscope, flow cytometry, and immunohistochemistry. …”
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Metformin attenuates V-domain Ig suppressor of T-cell activation through the aryl hydrocarbon receptor pathway in Melanoma: In Vivo and In Vitro Studies
Published 2021“…This study aims to investigate the inhibitory effect of metformin on VISTA via AHR in melanoma cells (CHL-1, B16) and animal models. VISTA and AHR levels were assessed by qPCR, Western blot, immunofluorescence microscope, flow cytometry, and immunohistochemistry. …”
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Structural and magnetic properties of Ni1-xZnxFe 2O4 (x=0, 0.5 and 1) nanopowders prepared by sol-gel method
Published 2013“…As the grain size increased, the Curie temperature of NiFe 2O4 increased from 849 to 859 K. The highest saturation magnetization of 70 emu/g at 298 K and the highest specific heating rate of 1.6 K/s under radiofrequency heating at 295 kHz were observed over NiFe 2O4 calcined at 1073 K. …”
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Investigation of solar PV performance under Doha weather using a customized measurement and monitoring system
Published 2016“…Results predict that the maximum power output from a Poly-crystalline panel decreases by around 30% for a dust exposure of five months. …”
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Optimizing nutrient removal of moving bed biofilm reactor process using response surface methodology
Published 2020“…The potential of 3-stages process (anaerobic, anoxic and moving bed biofilm reactor (MBBR)) for organic matter and nutrient removals from secondary WWTP effluents at various hydraulic retention time (HRT) and nitrate recycle ratio (R) was investigated. …”
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Correlating the rheological and magneto-optical properties of cobalt substituted magnetite ferrofluids (CoxFe1?xFe2O4) with theoretical studies
Published 2023“…An environmental friendly method of co-precipitation is applied to generate CoxFe1?xFe2O4 with variable dopant concentration (x = 0-0.8), which is deeply investigated by structural and functional property analyses of the ferrofluids. …”
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Bench-scale and packed bed sorption of methylene blue using treated olive pomace and charcoal
Published 2006“…The breakthrough time increased with increasing bed height, decreasing flow rate and decreasing influent concentration and methylene blue dye uptake. …”
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Continuous adsorptive removal of glimepiride using multi-walled carbon nanotubes in fixed-bed column.
Published 2021“…The results showed that the drug removal is improved with the increasing bed height; however, it decreased with the flow rate. …”
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Uncovering the Epigenetic Contribution of Protein Arginine Methyltransferase 5 (PRMT5) during Zebrafish Cardiomyogenesis
Published 2020“…The reduction of the expression of PRMT5 also resulted in a 4-fold decrease in the rate of hatching and had negative impacts on locomotion and tail flicking in PRMT5 morphants. …”
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Fabrication of zno-fe-mxene based nanocomposites for efficient co2 reduction
Published 2020“…Nyquist plots also illustrated a decrease in the impedance of the ZnO-Fe-MXene layer, indicating fast charge transfer between the Zn and MXene layers. …”
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Protein arginine methyltransferase 5 (PRMT5) promotes survival of lymphoma cells via activation of WNT/B-catenin and AKT/GSK3B proliferative signaling
Published 2019“…We show that PRMT5 stimulates WNT/B-CATENIN signaling through direct epigenetic silencing of pathway antagonists, AXIN2 and WIF1, and indirect activation of AKT/GSK3 signaling.PRMT5 inhibition with either shRNA-mediated knockdown or a specific small molecule PRMT5 inhibitor, CMP-5, not only leads to derepression of WNT antagonists and decreased levels of active phospho-AKT (Thr-450 and Ser-473) and inactive phospho- GSK3B (Ser-9) but also results in decreased transcription of WNT/B-CATENIN target genes, CYCLIN D1, c-MYC, and SURVIVIN, and enhanced lymphoma cell death. …”
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Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle
Published 2023“…We found both young and aged HSA-mUCP1 mice had decreased advanced glycation endproducts (AGEs) formed from MG, lysine-derived Nε(1-carboxyethyl)lysine (CEL) and arginine-derived hydroimidazolone, MG-H1, whereas protein glycation by glucose forming Nε-fructosyl-lysine (FL) was increased ca. 2-fold, compared to wildtype controls. …”
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Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle
Published 2023“…We found both young and aged HSA-mUCP1 mice had decreased advanced glycation endproducts (AGEs) formed from MG, lysine-derived Nε(1-carboxyethyl)lysine (CEL) and arginine-derived hydroimidazolone, MG-H1, whereas protein glycation by glucose forming Nε-fructosyl-lysine (FL) was increased ca. 2-fold, compared to wildtype controls. …”
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Numerical analysis of spatial distribution of carbon in methane dry reforming over supported nickel catalyst in a packed bed reactor
Published 2024“…This study investigates carbon deposition during methane dry reforming over a nickel-based catalyst supported on alumina in a laboratory-scale fixed-bed reactor. Approximately 23.75 g of catalyst was used, and simulations were performed using COMSOL 6.2 software. …”
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Magneto-Mechanical and Thermal Properties of Nd-Fe-B-Epoxy-Bonded Composite Materials
Published 2023“…The results show that impact toughness decreases, while magnetic properties increase, along with increasing content of Nd-Fe-B. …”
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Adsorption of Congo Red Dye Using Activated Carbon-Fe3O4 Composite
Published 2023“…Initial dye concentration also had significant impact on the adsorption process as the adsorption capacity of the AC- Fe3O4 adsorbents decreased with increase in dye concentrations. …”
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Effect of Hydrothermal Carbonization Parameters and Performance of Carbon Dioxide Adsorption on Pineapple Peel Waste Biochar
Published 2022“…The CO2 adsorption performance of PPW biochar (PPW-BC) in a fixed-bed column was successfully predicted by the Thomas and Yoon-Nelson models. …”
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